Results 31 to 40 of about 2,814,854 (281)

Antimicrobial Peptides and Skin: A Paradigm of Translational Medicine [PDF]

, 2012
Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important ...
Schöllmann, C., Korting, Hans Christian, Schäfer-Korting, Monika, Stauss-Grabo, M.   +3 more
core   +1 more source

T Cell Immunity to the Alkyl Hydroperoxide Reductase of Burkholderia pseudomallei: A Correlate of Disease Outcome in Acute Melioidosis. [PDF]

, 2015
There is an urgent need for a better understanding of adaptive immunity to Burkholderia pseudomallei, the causative agent of melioidosis that is frequently associated with sepsis or death in patients in Southeast Asia and Northern Australia.
Sumonwiriya, M, Makinde, Julia, Reynolds, Catherine, Altmann, D, Quigley, K, Rinchai, Darawan, Overbeek, S, Boyton, R, Yos, Pagnarith, Jenjaroen, Kemajittra, Maillere, Bernard, Manji, J, Yos, P, Reynolds, C, Musson, Julie, Overbeek, Saskia, Manji, Jiten, Spink, N, Bancroft, Gregory, Musson, J, Dunachie, S, Quigley, Kathryn, Bancroft, G, Goudet, Amélie, Wuthiekanun, Vanaporn, Wuthiekanun, V, Altmann, Daniel, Robinson, John, Lertmemongkolchai, Ganjana, Makinde, J, Rinchai, D, Robinson, J, Lertmemongkolchai, G, Holden, Matthew, Maillere, B, Dunachie, Susanna, Goudet, A, Holden, M, Jenjaroen, K, Spink, Natasha, Boyton, Rosemary, Sumonwiriya, Manutsanun, Holden, Matthew; id_orcid   +42 more
core   +1 more source

Flagellin, a plant-defense-activating protein identified from Xanthomonas axonopodis pv. Dieffenbachiae invokes defense response in tobacco

BMC Microbiology, 2023
Background Secretome analysis is a valuable tool to study host-pathogen protein interactions and to identify new proteins that are important for plant health.
Tamilarasi Mani, J. Beslin Joshi, R. Priyadharshini, Jeya Sundara Sharmila, Sivakumar Uthandi   +4 more
doaj   +1 more source

Defense pathways in Arabidopsis restricting compatible tobamoviruses during infection [PDF]

, 2014
Virus infected plants often develop strong disease symptoms including leaf deformation, chlorosis, necrosis and growth inhibition. In agriculture systems virus infection can lead to severe yield losses and a better understanding of plant defenses against
Kørner, Camilla Julie
core   +1 more source

SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense.

PLoS Pathogens, 2021
The skin innate immune response to methicillin-resistant Staphylococcus aureus (MRSA) culminates in the formation of an abscess to prevent bacterial spread and tissue damage.
Nathan Klopfenstein, Stephanie L Brandt, Sydney Castellanos, Matthias Gunzer, Amondrea Blackman, C Henrique Serezani   +5 more
doaj   +1 more source

Evolving and assembling to pierce through: Evolutionary and structural aspects of antimicrobial peptides

Computational and Structural Biotechnology Journal, 2022
The burgeoning menace of antimicrobial resistance across the globe has necessitated investigations into other chemotherapeutic strategies to combat infections.
Sukriyo Chakraborty, Ritika Chatterjee, Dipshikha Chakravortty   +2 more
doaj   +1 more source

Differential expression of immune defences is associated with specific host-parasite interactions in insects [PDF]

, 2009
Recent ecological studies in invertebrates show that the outcome of an infection is dependent on the specific pairing of host and parasite. Such specificity contrasts the long-held view that invertebrate innate immunity depends on a broadspectrum ...
Carolyn Riddell, Riddell, Carolyn, Eamonn B. Mallon (7514327), Adams, Sally, Sally Adams, Schmid-Hempel, Paul, Mallon Eamonn B., Schmid-Hempel Paul, Carolyn Riddell (257705), Paul Schmid-Hempel, S. Adams (1469704), Mallon, Eamonn B., Eamonn B Mallon, Adams Sally, Riddell Carolyn, Ridell, Carolyn, P. Schmid-Hempel (7607216)   +16 more
core   +2 more sources

Host Defense Peptides in Wound Healing

Molecular Medicine, 2008
Host defense peptides are effector molecules of the innate immune system. They show broad antimicrobial action against gram-positive and -negative bacteria, and they likely play a key role in activating and mediating the innate as well as adaptive immune response in infection and inflammation. These features make them of high interest for wound healing
Lars, Steinstraesser, Till, Koehler, Frank, Jacobsen, Adrien, Daigeler, Ole, Goertz, Stefan, Langer, Marco, Kesting, Hans, Steinau, Elof, Eriksson, Tobias, Hirsch   +9 more
openaire   +2 more sources

Transcriptomic analyses reveal comprehensive responses of insect hemocytes to mycopathogen Beauveria bassiana, and fungal virulence-related cell wall protein assists pathogen to evade host cellular defense

Virulence, 2020
Entomopathogenic fungi naturally infect insect hosts in environment. Fungal invasion and host immune defense are still in the progress of co-evolution. In this study, entomopathogenic fungus Beauveria bassiana and lepidopteran insect Galleria mellonella ...
Jin-Li Ding, Jia Hou, Ming-Guang Feng, Sheng-Hua Ying   +3 more
doaj   +1 more source

Cell-density dependence of host-defense peptide activity and selectivity in the presence of host cells [PDF]

, 2016
Host-defense peptides (HDPs) are promising compounds against multidrug-resistant microbes. In vitro, their bactericidal and toxic concentrations are significantly different, but this might be due to the use of separate assays, with different cell ...
Savini F., Bocedi, A, Bocedi A., Alessio Bocedi (235459), Lorenzo Stella (235473), Vincenzo Luca (304649), Maria Luisa Mangoni (304656), Park, Y, Stella, L, Mangoni M. L., Renato Massoud (3390122), Luca V., Stella L., Mangoni, Ml, Massoud R., Massoud, R, Yoonkyung Park (199734), Savini, F, Luca, V, Park Y., Filippo Savini (3390119), Savini, Filippo, Massoud, Renato, Park, Yoonkyung, Bocedi, Alessio, Stella, Lorenzo, LUCA, VINCENZO, MANGONI, Maria Luisa   +27 more
core   +1 more source