Results 51 to 60 of about 2,814,854 (281)

Modulation of host antimicrobial peptide (beta-defensins 1 and 2) expression during gastritis [PDF]

, 2002
Background: beta-Defensins are a newly identified family of antimicrobial peptides that are expressed by epithelia on mucosal surfaces where their production is augmented by infection or inflammation.
Domizio, P., Bajaj-Elliott, M., Ali, R.S., Domizio, P, Maher, L, Fedeli, P, Farthing, MJG, Fedeli, P., M Bajaj-Elliot (16115810), Quinn, AG, Smith, G.V, Quinn, A.G., Ali, RS, P Domizio (16116209), M J Farthing (16115624), Bajaj-Elliott, M, Maher, L., Farthing, M.J.G., P Fedeli (16116206), R S Ali (16116212), Smith, GV, R G Quinn (16116215), G V Smith (16115678), L Maher (9856208)   +23 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Characterization of genes coding for small hypervariable peptides in Globodera rostochiensis [PDF]

, 2008
Plant parasitic nematodes secrete a cocktail of effector molecules, which are involved in several aspects of the interaction with the host, eg. in host defense suppression, in migration and in feeding cell formation.
Bers, N.E.M., van
core  

Discovery and mechanisms of host defense to oncogenesis: Targeting the β-defensin-1 peptide as natural tumor inhibitor [PDF]

, 2019
Human beta-defensin-1 (hBD-1) is one of a number of small cationic host-defense peptides. Besides its well-known broad-spectrum antimicrobial function, hBD-1 has recently been identified as a chromosome 8p tumor-suppressor gene.
Q. Sun, Carrie, Li, Zhenghong, Arnold, Rebecca, Lian, Fei, Petros, John A., Dorin, Julia R., Hsieh, Chia-Ling, Rebecca S. Arnold, Julia R. Dorin, John A. Petros, Carrie Q. Sun, Zhenghong Li, Chia-Ling Hsieh, Fei Lian   +13 more
core   +1 more source

Optimizing Antimicrobial Host Defense Peptides

Chemistry & Biology, 2006
Antimicrobial host defense peptides constitute a major component of innate immune systems. Expectations are high to develop them into a novel class of anti-infective agents. In this issue of Chemistry & Biology, Hilpert et al. describe new design and peptide synthesis strategies for systematically investigating such concepts.
openaire   +2 more sources

New horizons for host defense peptides and lantibiotics [PDF]

Current Opinion in Pharmacology, 2012
Antimicrobial peptides from either microbial sources, or based on host defense peptides (HDPs) from higher organisms, show promising activity against human pathogens. Lantibiotics have been extensively engineered by either molecular biology approaches or chemistry and both natural and modified entities have been shown to have good efficacy in animal ...
Michael John, Dawson, Richard W, Scott
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Pseudomonas aeruginosa elastase cleaves a C-terminal peptide from human thrombin that inhibits host inflammatory responses

Nature Communications, 2016
Neutrophil elastase cleaves thrombin generating anti-inflammatory peptides. Here the authors show that cleavage of thrombin by Pseudomonas aeruginosaelastase generates a peptide that prevents TLR dimerization and signaling, interfering with the ...
Mariena J. A. van der Plas, Ravi K. V. Bhongir, Sven Kjellström, Helena Siller, Gopinath Kasetty, Matthias Mörgelin, Artur Schmidtchen   +6 more
doaj   +1 more source

Suppression of soft tissue sarcoma growth by a host defense-like lytic peptide. [PDF]

PLoS ONE, 2011
BACKGROUND: Soft tissue sarcoma (STS) is an anatomically and histologically heterogeneous neoplasia that shares a putative mesenchymal cell origin.
Lars Steinstraesser, Jennifer Hauk, Cornelius Schubert, Sammy Al-Benna, Ingo Stricker, Hanns Hatt, Yechiel Shai, Hans-Ulrich Steinau, Frank Jacobsen   +8 more
doaj   +1 more source

Peptide-Loaded Microgels as Antimicrobial and Anti-Inflammatory Surface Coatings

, 2018
Here we report on covalently immobilized poly­(ethyl acrylate-co-methacrylic acid) microgels loaded with the host defense peptide KYE28 (KYEITTIH­NLFRKLTHRL­FRRNFGYTLR), which is derived from human heparin cofactor II, as well as its poly­(ethylene ...
Artur Schmidtchen (109609), Lina Nyström (1495915), Malmsten, Martin, Nyström, Lina, Schmidtchen, Artur, Lina Nyström, Martin Malmsten, Adam A. Strömstedt, Artur Schmidtchen, Strömstedt, Adam A., Adam A. Strömstedt (3614618), Martin Malmsten (109608), Strömstedt, Adam A.,, Schmidtchen, Artur,, Malmsten, Martin,, Nyström, Lina,   +15 more
core   +1 more source