Human and animal dietary exposure to T-2 and HT-2 toxin. [PDF]
EFSA J, 2017 T-2 toxin (T2) and HT-2 (HT2) toxin are trichothecenes, which form part of the group of Fusarium mycotoxins. Food and feed samples used to estimate human dietary and animal exposure were reported either as the individual results for T2 and/or, HT2, and/or as the sum of the two.
European Food Safety Authority (EFSA) +4 more
europepmc +3 more sources
T-2 and HT-2 Toxins: Toxicity, Occurrence and Analysis: A Review
Toxins, 2023 One of the major classes of mycotoxins posing serious hazards to humans and animals and potentially causing severe economic impact to the cereal industry are the trichothecenes, produced by many fungal genera.
Julie Meneely +3 more
doaj +5 more sources
Comparison of Anorectic Potencies of Type A Trichothecenes T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol. [PDF]
Toxins (Basel), 2018 Trichothecene mycotoxins are common contaminants in cereal grains and negatively impact human and animal health. Although anorexia is a common hallmark of type B trichothecenes-induced toxicity, less is known about the anorectic potencies of type A trichothecenes.
Zhang J, Zhang H, Liu S, Wu W, Zhang H.
europepmc +4 more sources
Debunking the Myth of Fusarium poae T-2/HT-2 Toxin Production. [PDF]
J Agric Food ChemFusarium poae is commonly detected in field surveys of Fusarium head blight (FHB) of cereal crops and can produce a range of trichothecene mycotoxins. Although experimentally validated reports of F. poae strains producing T-2/HT-2 trichothecenes are rare, F.
Witte TE +4 more
europepmc +3 more sources
Comparison of anorectic potencies of the trichothecenes T-2 toxin, HT-2 toxin and satratoxin G to the ipecac alkaloid emetine [PDF]
Toxicology Reports, 2015 Trichothecene mycotoxins, potent translational inhibitors that are associated with human food poisonings and damp-building illnesses, are of considerable concern to animal and human health.
Wenda Wu +3 more
doaj +2 more sources
T-2 Toxin/HT-2 Toxin and Ochratoxin A ELISAs Development and In-House Validation in Food in Accordance with Commission Regulation (EU) No 519/2014 [PDF]
Toxins, 2017 T-2 toxin/HT-2 toxin (T-2/HT-2) and ochratoxin A (OTA) are mycotoxins that can contaminate a variety of agricultural commodities. To protect consumers’ health, indicative limits for T-2/HT-2 and maximum limits for OTA have been set by the European ...
Michalina Oplatowska-Stachowiak +6 more
doaj +2 more sources
Exposure to HT-2 toxin causes oxidative stress induced apoptosis/autophagy in porcine oocytes. [PDF]
Sci Rep, 2016 AbstractT-2 toxin is a main type A trichothecene mycotoxin which is the most toxic trichothecence. T-2 toxin has posed various toxic effects on human and animals in vigorous cell proliferation tissues like lymphoid, hematopoietic and gastrointestinal tissues, while HT-2 toxin is the major metabolite which is deacetylated by T-2 toxin. In this study, we
Zhang Y +6 more
europepmc +4 more sources
Ecotoxicology and Environmental SafetyHT-2 toxin, a type A trichothecene mycotoxin produced by fungi such as Fusarium, is widely present in nature in moldy crops and adversely affects mammalian reproduction. Melatonin, a natural antioxidant, exhibits protective effects on cells.
Fei Wu +7 more
doaj +2 more sources
Biotechnology-enhanced immunoassay for accurate determination of HT-2 toxin in edible insect samples. [PDF]
Mikrochim ActaAbstract Consumption of edible insects is common in non-Western countries of Africa, Asia, Oceania, and Latin America. However, their consumption has significantly increased in Europe in recent years thanks to their remarkable nutritional properties.
Sancho-García R +6 more
europepmc +5 more sources
Influence of T-2 and HT-2 toxin on the blood-brain barrier in vitro: new experimental hints for neurotoxic effects. [PDF]
PLoS ONE, 2013 The trichothecene mycotoxin T-2 toxin is a common contaminant of food and feed and is also present in processed cereal derived products. Cytotoxic effects of T-2 toxin and its main metabolite HT-2 toxin are already well described with apoptosis being a ...
Maria Weidner +5 more
doaj +2 more sources