Results 31 to 40 of about 192,493 (241)

Serum Human Epididymis Protein 4 is a Potential Biomarker for Early Chronic Kidney Disease in an Obese Population

Diabetes, Metabolic Syndrome and Obesity, 2021
Shubo Tan, Yongmao Zeng, Shiliang Kuang, Jianjun Li Department of Urology, Second Affiliated Hospital of the University of South China, Hengyang City, 421000, People’s Republic of ChinaCorrespondence: Jianjun LiDepartment of Urology, Second ...
Tan S, Zeng Y, Kuang S, Li J
doaj   +2 more sources

Correlation of Human Epididymis Protein 4 Expression with Clinicopathologic Parameters in Gastric Carcinomas

Hamidiye Medical Journal
Background: Human epididymis protein 4 (HE4) was discovered in 1991 as a glycoprotein secreted from the cells of the human epididymal epithelium and associated with sperm development and immunity.
Pınar Öksüz, Gülden Diniz, Talya Akata, Yetkin Koca, Duygu Ayaz   +4 more
doaj   +2 more sources

Three-Dimensional Structure of Human Epididymis Protein 4 (HE4): A Protein Modelling of an Ovarian Cancer Biomarker Through In Silico Approach

Journal of Tropical Life Science
The Human Epididymis Protein 4 (HE4) biomarker has been extensively investigated for its potential in diagnosing ovarian cancer (OC). For the application of diagnostic techniques and drug delivery, it is crucial to understand the protein tertiary ...
Nur Nadiah Abdul Rashid, Mohd Hamzah Mohd Nasir, Nurasyikin Hamzah, Che Muhammad Khairul Hisyam Ismail, Siti Aishah Sufira Nor Hishamuddin, Izzat Fahimuddin Mohamed Suffian, Azzmer Azzar Abdul Hamid   +6 more
doaj   +2 more sources

MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension [PDF]

Cardiovascular Therapeutics, 2022
Background. Pulmonary arterial hypertension (PAH) usually causes right ventricular dysfunction, which is closely related to cardiac fibrosis. But cardiac fibrosis mechanism remains unclear.
Yi Tang, Xiaowei Huo, Junyu Liu, Yijin Tang, Min Zhang, Wenlin Xie, Zhaofen Zheng, Jin He, Jiayan Lian   +8 more
doaj   +2 more sources

Association Between Serum Human Epididymis Protein 4 Levels and Cardiovascular Events in Obese Patients with Breast Cancer [PDF]

Diabetes, Metabolic Syndrome and Obesity, 2021
Li Wang,1 Nie Hu,1 Zhongjun Jiang,1 Ping Luo,1 Nian Yi,1 Yanhua Chen,2 Ning Zhou,2 Longfei Liu2 1Department of Breast Surgery, Nanhua Hospital, Nanhua University, Hengyang City, Hunan Province, 421002, People’s Republic of China; 2Department of General ...
Wang L, Hu N, Jiang Z, Luo P, Yi N, Chen Y, Zhou N, Liu L   +7 more
doaj   +2 more sources

Human Epididymis Protein 4 (HE4) as a promising biomarker and therapy target in fibrotic diseases: A review

Journal of Holistic Integrative Pharmacy
The treatment of fibrosis faces a significant challenge due to the lack of effective therapies that can reverse established fibrosis. Early detection is vital for intervention, yet distinguishing fibrosis from normal tissue repair is complex.
Huiqun Tian, Li Chen
doaj   +2 more sources

Serum human epididymis Protein-4 outperforms conventional biomarkers in the early detection of non-small cell lung cancer. [PDF]

iScience
Zare ME, Nasir Kansestani A, Wu X, Zhou L, Lu J, Huang J, Wang Y, Ma Y, Gao Y, Zhang J.   +9 more
europepmc   +2 more sources

Human Epididymis Protein 4 Levels in Neonates with Respiratory Disorder. [PDF]

Biomed Res Int, 2020
Introduction. Transient tachypnea of the newborn (TTN) is one of the most common causes of respiratory distress in the full‐term neonates. The diagnosis of TTN in early postnatal period remains problematic for clinicians, and unfortunately, there exist no reliable diagnostic tests for TTN.
Surmiak P, Szymkowiak M, Baumert M.
europepmc   +5 more sources

HE4 level in ascites may assess the ovarian cancer chemotherapeutic effect

Journal of Ovarian Research, 2018
Background The clinical treatment of ovarian cancer with ascites is problematic. The main reasons for treatment failure are the susceptibility to intraperitoneal metastasis and chemotherapeutic drug resistance.
Duanyang Liu, Dan Kong, Jing Li, Lei Gao, Di Wu, Yu Liu, Weiwei Yang, Lei Zhang, Jiang Zhu, Xiaoming Jin   +9 more
doaj   +1 more source

Co-expression of Lewis y antigen with human epididymis protein 4 in ovarian epithelial carcinoma. [PDF]

PLoS ONE, 2013
OBJECTIVE:The main aims of this study were to explore the molecular structural relationship between Human epididymis protein 4 (HE4) and Lewis y antigen by determining their expression patterns and clinical significance in ovarian epithelial carcinoma ...
Huiyu Zhuang, Jian Gao, Zhenhua Hu, Juanjuan Liu, Dawo Liu, Bei Lin   +5 more
doaj   +1 more source