Results 31 to 40 of about 4,132 (213)
Journal of Fungi, 2023 Huperzine A (HupA) is an important drug for treating Alzheimer’s disease (AD) and is primarily extracted from the Huperzia serrata (Lycopodiaceae). Failures in the chemical synthesis of Hup and in vitro culture have put H. serrata in danger of extinction,
Thanh Thi Minh Le +4 more
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Huperzine A for treatment of cognitive impairment in major depressive disorder: A systematic review of randomized controlled trials [PDF]
, 2016 Background: Acetylcholinesterase (AChE) inhibitors have been shown to be effective in treating cognitive impairment in animal models and in human subjects with major depressive disorder (MDD).
Chiu, Helen +6 more
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PLoS ONE, 2013 BackgroundHuperzine A is a Chinese herb extract used for Alzheimer's disease. We conducted this review to evaluate the beneficial and harmful effect of Huperzine A for treatment of Alzheimer's disease.MethodsWe searched for randomized clinical trials ...
Guoyan Yang +3 more
doaj +1 more source
Huperzine A - An Interesting Anticholinesterase Compound from the Chinese Herbal Medicine
Acta Medica, 1998 Huperzine A, alkaloid from the Chinese herbal medicine Qian Ceng Ta, which is prepared from the moss Huperzia serrata, has been used in China for centuries to treat fever and inflammation.
Jiří Patočka
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One-step synthesis of Lycopodium alkaloid (-)-huperzine W via Suzuki-Miyaura coupling [PDF]
, 2012 The first total synthesis of (−)-huperzine W (1) has been achieved. Key element of the synthesis is a highly convergent assemblage for the two rings system of target molecule utilizing an efficient Suzuki-Miyaura coupling reaction between chiral iodide 2
Huai-Rong Luo +3 more
core +1 more source
Drug Delivery, 2020 Increasingly attention has been paid to the transdermal drug delivery systems with microneedles owing to their excellent compliance, high efficiency, and controllable drug release, therefore, become promising alternative with tremendous advantages for ...
Qinying Yan +9 more
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Physiological Reports, 2022 Acetylcholine (ACh) may be involved in the regulation of ovarian functions. A previous systemic study in rats showed that a 4‐week, intrabursal local delivery of the ACh‐esterase blocker Huperzine‐A increased intraovarian ACh levels and changed ovarian ...
Fernanda C. Cuevas +8 more
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Tyrosine-based rivastigmine-loaded organogels in the treatmant of Alzheimer's disease [PDF]
, 2010 Faculté de PharmacieOrganogels can be prepared by immobilizing an organic phase into a threedimensional network coming from the self-assembly of a low molecular weight gelator molecule.
Bastiat, Guillaume +7 more
core +4 more sources
Interventions to delay functional decline in people with dementia: a systematic review of systematic reviews. [PDF]
, 2016 This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative ...
Clemson, Lindy +4 more
core +1 more source
Plant Direct, 2021 Huperzia serrata (H. serrata) produces various types of effective lycopodium alkaloids, especially Huperzine A (HupA), which is a promising drug for the treatment of Alzheimer's disease.
Yanping Fu +5 more
doaj +1 more source