Results 81 to 90 of about 13,103 (221)

A Monte Carlo study on dose enhancement and photon contamination production by various nanoparticles in electron mode of a medical linac [PDF]

, 2015
The aim of this study is the evaluation of electron dose enhancement and photon contamination production by various nanoparticles in the electron mode of a medical linac. MCNPX Monte Carlo code was used for simulation of Siemens Primus linac as well as a
Akbari, Fateme, Ghorbani, Mahdi, Mehrpouyan, Mohammad, Sabet, Leila Sobhkhiz, Toossi, Mohammad Taghi Bahreyni   +4 more
core   +1 more source

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae, Jessica Marie Hunter Alberhasky, Marion Baillet, Debra A. Bangasser, Michael E. Belloy, Anne S. Berry, Chiara Berteotti, Hannah Bow, Rachel Buckley, Jessica Z. K. Caldwell, Matteo Carpi, Benjamin J. Clark, Claire J. Ciampa, Alexander C. Conley, Martin J. Dahl, Zoe R. Donaldson, Alexander J. Ehrenberg, Gillian Einstein, Neus Falgàs, Haley A. Fenlon, Megan C. Fitzhugh, Robert C. Froemke, Clara Gallay, Lea Tenenholz Grinberg, Derek A. Hamilton, Zia Hasan, Oihane Uriarte Huarte, Shaista Jabeen, Heidi I. L. Jacobs, Louis John Kolling, Elouise A. Koops, Sabrina Lenzoni, Claudio Liguori, Riccardo Manca, Catherine A. Marcinkiewcz, Tamunotonye Omoluabi, Rademene Oria, Caitlin A. Orsini, Nancy Elizabeth Ortega, Judy Pa, Nathan S. Pentkowski, Joana B. Pereira, Rhudovic Ramos, Derya Sargin, Abhijit Satpati, Maria Clara Selles, Mabel Seto, Shabana M. Shaik, Shireen Sindi, Gowoon Son, Valentine Ucheagwu, Maxime Van Egroo, Qi Yuan, Michael A. Kelberman   +53 more
wiley   +1 more source

Recruitment of hypothalamic orexin neurons after formalin injections in adult male rats exposed to a neonatal immune challenge

Frontiers in Neuroscience, 2015
Exposure to early life physiological stressors, such as infection, is thought to contribute to the onset of psychopathology in adulthood. In animal models, injections of the bacterial immune challenge, lipopolysaccharide (LPS), during the neonatal period
Erin Jane Campbell, Stephanie M Watters, Ihssane eZouikr, Deborah M Hodgson, Christopher V Dayas   +4 more
doaj   +1 more source

Trypanosoma brucei brucei invasion and T-cell infiltration of the brain parenchyma in experimental sleeping sickness: timing and correlation with functional changes [PDF]

, 2016
Background: The timing of Trypanosoma brucei entry into the brain parenchyma to initiate the second, meningoencephalitic stage of human African trypanosomiasis or sleeping sickness is currently debated and even parasite invasion of the neuropil has ...
Bentivoglio, Marina, Bradley, Barbara, Etet, Paul F. Seke, Grassi-Zucconi, Gigliola, Kennedy, Peter G.E., Laperchia, Claudia, Montague, Paul, Palomba, Maria, Rodgers, Jean   +8 more
core   +4 more sources

Wake‐promoting neuromodulators in Alzheimer's disease: Implications for sleep and brain clearance

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Neuromodulatory subcortical systems (NSS) regulate arousal, cognition, and sleep–wake transitions through widespread influence on cortical and subcortical networks. Increasing evidence links dysfunction of these systems to the pathogenesis of Alzheimer's disease (AD). Degeneration and dysregulation of NSS occurs during the preclinical phase of
Taylor J. Pedersen, Sabrina G. Clemens, Joseph R. Winer, Ashish Sharma, Neus Falgàs, Brendan P. Lucey, Brian A. Gordon, Erik S. Musiek   +7 more
wiley   +1 more source

Pharmacological profiling of zebrafish behavior using chemical and genetic classification of sleep-wake modifiers

Frontiers in Pharmacology, 2015
Sleep-wake states are impaired in various neurological disorders. Impairment of sleep-wake states can be an early condition that exacerbates these disorders. Therefore, treating sleep-wake dysfunction may prevent or slow the development of these diseases.
Yuhei eNishimura, Yuhei eNishimura, Yuhei eNishimura, Yuhei eNishimura, Yuhei eNishimura, Shiko eOkabe, Shota eSasagawa, Soichiro eMurakami, Yoshifumi eAshikawa, Mizuki eYuge, Koki eKawaguchi, Reiko eKawase, Toshio eTanaka, Toshio eTanaka, Toshio eTanaka, Toshio eTanaka, Toshio eTanaka   +16 more
doaj   +1 more source

Hypocretin neurotransmitter system and narcolepsy

Vojnosanitetski pregled, 2008
<zakljucak> Prelomno otkrice nedostatka hipokretina kod narkolepsije pruza izvrsnu osnovu za bolje razumevanje fiziologije spavanja i podsticaj je za buduca istrazivanja. Medjutim, ono nije omogucilo da se razresi enigma etiologije narkolepsije.
Lakočević Milan B., Rajšić Nenad R.
openaire   +3 more sources

Systematic Review on the Association Between Sleep and the Risk of Alzheimer’s Disease: An Evolutionary Perspective

Evolutionary Applications, Volume 19, Issue 3, March 2026.
ABSTRACT Alzheimer's disease (AD) is an important, non‐curable disease today. Several possible risk factors have been discussed, among others sleep. Evolutionary hypotheses were proposed to explain sleep variation and AD risk, such as a potential advantage of short or interrupted sleep in ancient insecure environments, the evolution of increased ...
S. E. Spirig, S. Frei, A. V. Jaeggi, N. Bender   +3 more
wiley   +1 more source

Relato de dois casos de pacientes com narcolepsia com melhora dos sintomas após uso de prednisona [PDF]

, 2007
This article focuses on 2 clinical case reports of narcoleptic patients who experienced an absence of excessive sleepiness during treatment of other illnesses with 40 mg daily intake of prednisone.Este artigo refere-se à discussão de 2 casos de pacientes
Alves, Gabriela Rodrigues, Bittencourt, Lia Rita Azeredo, Coelho, Fernando Morgadinho Santos, Pradella-Hallinan, Márcia Lurdes de Cássia, Tufik, Sergio   +4 more
core   +2 more sources

Impaired adrenergic regulation of Kv channels underlies LC hyperactivity and early‐onset sleep disruption in AD‐like amyloidogenic mice

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sleep–wake disturbances frequently occur at early stages of Alzheimer's disease (AD) and accelerate disease progression, but the underlying neural mechanisms are not fully understood. METHODS We examined sleep–wake behavior and locus coeruleus (LC) activity in young 5xFAD mice using electrophysiology and pharmacological approaches
Yi‐Ci Zhang, Xue‐Ting Zhang, Peng‐Yue Chen, Zi‐Yue Zhou, Mao‐Qing Huang, Kai‐Wen He   +5 more
wiley   +1 more source