Results 71 to 80 of about 69,683,828 (280)
Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy
OncoImmunology, 2018 Cytokines regulate virtually aspects of innate and adaptive immunity, including the initiation, execution and extinction of tumor-targeting immune responses. Over the past three decades, the possibility of using recombinant cytokines as a means to elicit
Elena García-Martínez +12 more
doaj +1 more source
IL-15–High-Responder Developing NK Cells Bearing Ly49 Receptors in IL-15−/− Mice [PDF]
, 2011 In mice lacking IL-15, NK cell development is arrested at immature stages, providing an opportunity to investigate the earliest developing NK cells that would respond to IL-15.
Katsumi Yoshizawa +11 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz +6 more
wiley +1 more source
BMC Immunology, 2021 Background Interleukin (IL)-15 is a proinflammatory T-cell growth factor overexpressed in several autoimmune diseases such as rheumatoid arthritis. Our initial strategy to neutralize the increased levels of IL-15 consisted in a vaccine candidate based on
Yunier Rodríguez-Álvarez +6 more
doaj +1 more source
, 2023 BackgroundThe tumor microenvironment (TME) provides a conducive environment for the growth and survival of tumors. Negative factors present in TME, such as IL-10, may limit the effectiveness of cellular vaccines based on dendritic cells, therefore, it is
Anna Wróblewska +17 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad +9 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen +10 more
wiley +1 more source
IL-15 fosters age-driven regulatory T cell accrual in the face of declining IL-2 levels
Frontiers in Immunology, 2013 We and others have shown that regulatory T cells (Treg) accumulate dramatically with age in both humans and mice. Such Treg accrual contributes to age-related immunosenescence as they reduce the response to tumors and parasite infection.
Jana eRaynor +10 more
doaj +1 more source
IL-15 is produced in the thymus and its receptors are expressed by SP8 CD44hi thymocytes.
, 2019 Thymocytes from T. cruzi-infected (Tulahuen) WT mice were obtained 14 days after infection. The expression of (A) IL-2/IL-15 β chain (CD122) in SP8 CD44hi and CD44lo thymocytes was evaluated by Flow cytometry.
Jimena Tosello (6175385) +10 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau +8 more
wiley +1 more source