Results 51 to 60 of about 69,683,828 (280)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld +5 more
wiley +1 more source
IL-15 is required for obesity-induced inflammation.
, 2016 (A) Quantitative PCR analysis of Il15 expression of adipose tissues, liver and muscle of NCD or HFD -fed WT mice (mean±SEM; n = 3–4; †p(B) Quantitative PCR analysis of inflammatory genes of VAT, SAT and BAT of WT and Il15−/− male mice fed either NCD or ...
Mathieu Vernier (762951) +17 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo +9 more
wiley +1 more source
Immunologic Biomarkers in Peripheral Blood of Persons With Tuberculosis and Advanced HIV
Frontiers in Immunology, 2022 IntroductionTuberculosis (TB) is a common opportunistic infection among people living with HIV. Diagnostic tests such as culture, Xpert-MTB-RIF, and ULTRA have low sensitivity in paucibacillary TB disease; a blood biomarker could improve TB diagnostic ...
Artur T. L. Queiroz +38 more
doaj +1 more source
IL-15/IL-15Rα complexes as IL-15 superagonist [PDF]
, 2017 Interleukin 15 binds to its hight-afinity receptor IL-15Rα and forms stable IL-15/IL-15Rα complexes. IL-15Rα presents IL-15 in trans to target CD122/CD132 cells, where initiates signal transduction.
Honzírková, Lucie
core
IL-27 regulates IL-18 binding protein in skin resident cells [PDF]
, 2012 IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M +23 more
core +2 more sources
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source
Development of approaches for cellular immunotherapy of cancer patients
Медицинская иммунология, 2021 To treat the patients with oncological diseases, cellular immunotherapy have been actively developed in recent years. Usage of antitumor adoptive immunotherapy (AIT) based on in vitro activated lymphocytes and natural killer cells (NK cells) is the most ...
Yu. V. Gelm +3 more
doaj
Frontiers in Oncology, 2021 Immunotherapy is a promising new approach for cancer treatment. In this study, I propose to use the THαβ-mediated immune response for cancer treatment. The THαβ-mediated immune response is activated by IL-10 and IL-15.
Wan-Chung Hu, Wan-Chung Hu
doaj +1 more source
IL-15-deficient mice have reduced inflationary CD8 T cell maintenance.
, 2018 (A) Naïve C57BL/6 mice and IL-15-/- mice were infected i. v. with MCMVΔm157. Percentages of M38-specific CD8 T cells of total lymphocytes were longitudinally measured in the blood.
Koichi Ikuta (5100953) +10 more
core +1 more source