Results 101 to 110 of about 4,996,457 (177)

Characterization and spatial distribution of infiltrating lymphocytes in medullary, and lymphocyte-predominant triple negative breast cancers

npj Breast Cancer
Medullary carcinoma of the breast (MedBC) is a rare histological type that accounts for less than 5% of all invasive breast cancers. Here, we performed an exploratory study aimed to determine whether imaging mass cytometry (IMC) can be used to ...
A. Alfaro, C. Catelain, H. El-Masri, P. Rameau, M. Lacroix-Triki, JY. Scoazec, V. Marty, F. Mosele, B. Pistilli   +8 more
doaj   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

A proteotranscriptomic approach to dissect the molecular landscape of human retinoblastoma

Frontiers in Oncology
BackgroundRetinoblastoma is a rare pediatric eye cancer caused by mutations in the RB1 gene, which regulates retinal cell growth. Early detection and treatment are critical for preventing vision loss and improving survival outcomes.
Julian Wolf, Rozina Ida Hajdu, Stefaniya Boneva, Ira Godbole, Lucas Stürzbecher, Claudia Auw-Haedrich, Wolf A. Lagrèze, Hansjürgen Agostini, Thomas Reinhard, Stefan Tholen, Oliver Schilling, Günther Schlunck, Bertram Bengsch, Clemens Lange   +13 more
doaj   +1 more source

Biodistribution of nanoplastics in mice: advancing analytical techniques using metal-doped plastics

Communications Biology
Contamination of plastic particles in environmental and biological systems raises concerns regarding their potential negative impacts. Human exposure to microplastics (MPs) and nanoplastics (NPs) is increasing; however, some potential adverse health ...
Theresa Staufer, Verena Kopatz, Alice Pradel, Tess Brodie, Robert Kuhrwahl, Deborah Stroka, Julia Wallner, Lukas Kenner, Verena Pichler, Florian Grüner, Denise M. Mitrano   +10 more
doaj   +1 more source

Multimodal Mass Spectrometry Imaging of an Osteosarcoma Multicellular Tumour Spheroid Model to Investigate Drug-Induced Response

Metabolites
A multimodal mass spectrometry imaging (MSI) approach was used to investigate the chemotherapy drug-induced response of a Multicellular Tumour Spheroid (MCTS) 3D cell culture model of osteosarcoma (OS). The work addresses the critical demand for enhanced
Sophie M. Pearce, Neil A. Cross, David P. Smith, Malcolm R. Clench, Lucy E. Flint, Gregory Hamm, Richard Goodwin, James I. Langridge, Emmanuelle Claude, Laura M. Cole   +9 more
doaj   +1 more source

Abstract 1635: Multiplexed analysis of fixed tumor tissues using imaging mass cytometry

, 2017
Introduction: Comprehensive evaluation of the tumor microenvironment with preservation of spatial context requires simultaneous in situ detection of multiple targets.
Ila Datar, Narges Rashidi, Kurt A. Schalper, Amanda Esch, David L. Rimm, Daniel Carvajal-Hausdorf, Ala Nassar, Franz Villarroel-Espindola, Roy S. Herbst, Shelly Ren, Ruth R. Montgomery   +10 more
core   +1 more source

Imaging mass cytometry analysis of Becker muscular dystrophy muscle samples reveals different stages of muscle degeneration

Scientific Reports
Becker muscular dystrophy (BMD) is characterised by fiber loss and expansion of fibrotic and adipose tissue. Several cells interact locally in what is known as the degenerative niche.
Patricia Piñol-Jurado, José Verdú-Díaz, Esther Fernández-Simón, Cristina Domínguez-González, Aurelio Hernández-Lain, Conor Lawless, Amy Vincent, Alejandro González-Chamorro, Elisa Villalobos, Alexandra Monceau, Zoe Laidler, Priyanka Mehra, James Clark, Andrew Filby, David McDonald, Paul Rushton, Andrew Bowey, Jorge Alonso Pérez, Giorgio Tasca, Chiara Marini-Bettolo, Michela Guglieri, Volker Straub, Xavier Suárez-Calvet, Jordi Díaz-Manera   +23 more
doaj   +1 more source

ePoster

European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source

A New Method and Mass Spectrometer Design for TOF-SIMS Parallel Imaging MS/MS

, 2016
We report a method for the unambiguous identification of molecules in biological and materials specimens at high practical lateral resolution using a new TOF-SIMS parallel imaging MS/MS spectrometer.
Heeren, Ron M. A., Bryan, Scott R., Larson, Paul E., Fisher, Gregory L., Hammond, John S., Potocnik, Nina Ogrinc, Bruinen, Anne L.   +6 more
core   +1 more source

Spatial Autocorrelation in Mass Spectrometry Imaging

, 2016
Mass spectrometry imaging (MSI) is a powerful molecular imaging technique. In microprobe MSI, images are created through a grid-wise interrogation of individual spots by mass spectrometry across a surface.
McDonnell, L.A., Heeren, Ron M A, Ebert, M., Ebert, Matthias, Matthias Ebert (170342), Alberto Cassese (2635396), Shane R. Ellis (2021452), Cassese, A., Cassese, Alberto; id_orcid, Potocnik, N.O., Benjamin Balluff (253820), Walch, A.K., Eber, M., Maagdenberg, A.M.J.M. van den, Walch, A., Balluff, Benjamin, Heeren, R.M., Axel Walch (149177), Heeren, R.M.A., Cassese, Alberto, Walch, Axel, Ogrinc Potocnik, Nina, Burgermeister, E., Ellis, Shane R., Ron M. A. Heeren (213370), van den Maagdenberg, A.M., Elke Burgermeister (401842), Van Den Maagdenberg, Arn M J M, Ogrinc Potočnik, N., Balluff, B., Burgermeister, Elke, Ellis, S., Liam A. McDonnell (204773), Arn M. J. M. van den Maagdenberg (2803216), Nina Ogrinc Potočnik (1778278), McDonnell, Liam A., Ellis, S.R.   +36 more
core   +1 more source