Results 81 to 90 of about 4,996,457 (177)

GNL3 Orchestrates AR Transcriptional Programs to Drive Castration‐Resistant Prostate Cancer and Immune Evasion

Advanced Science, Volume 13, Issue 26, 8 May 2026.
GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang, Tin Long Cheong, Nitin Narwade, Dandan Dong, Mokan Deng, Zhengqiang Miao, Zhaoqiang Ding, Wenchao Li, Kate Man Kei Lei, Gong‐Hong Wei, Terence Chuen Wai Poon, Chu‐Xia Deng, Edwin Cheung   +12 more
wiley   +1 more source

Ultra-High Mass Resolving Power, Mass Accuracy, and Dynamic Range MALDI Mass Spectrometry Imaging by 21-T FT-ICR MS

, 2020
Detailed characterization of complex biological surfaces by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) requires instrumentation that is capable of high mass resolving power, mass accuracy, and dynamic range ...
Blakney, Greg T., Ellis, Shane R., Heeren, Ron M. A., Smith, Donald F., Bowman, Andrew P., Hendrickson, Christopher L.   +5 more
core   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Faster raster matrix-assisted laser desorption/ionization mass spectrometry imaging of lipids at high lateral resolution [PDF]

, 2019
The clinical use of mass spectrometry imaging (MSI) is rapidly growing, and applications are expanding. Crucially, the analysis of clinical cohorts requires a combination of higher analytical throughput and higher lateral resolution. Here, we demonstrate
Siegel, Tiffany Porta, Dewez, Frederic, Cillero-Pastor, Berta, Murray, Paul, Barre, Florian, Towers, Mark, Claude, Emmanuelle, Heeren, Ron, Rocha, Beatriz   +8 more
core   +2 more sources

Mass observation / by Mass Observation.

, 1945
Electronic reproduction. Canberra, A.C.T.
Mass-Observation.
core  

SpiDe-Sr: blind super-resolution network for precise cell segmentation and clustering in spatial proteomics imaging

Nature Communications
Spatial proteomics elucidates cellular biochemical changes with unprecedented topological level. Imaging mass cytometry (IMC) is a high-dimensional single-cell resolution platform for targeted spatial proteomics.
Rui Chen, Jiasu Xu, Boqian Wang, Yi Ding, Aynur Abdulla, Yiyang Li, Lai Jiang, Xianting Ding   +7 more
doaj   +1 more source

Precision Oncology Program (POP), an observational study using real-world data and imaging mass cytometry to explore decision support for the Molecular Tumor Board: study protocol

BMJ Open
Introduction Precision oncology aims to provide individualised treatment recommendations based on patient-specific characteristics. In this rapidly evolving field with increasing numbers of biomarkers and potential therapeutic targets, there is a growing
Charles Lu, Andreas Wicki, Shemra Rizzo, Dominik Glinz, Eva Camarillo-Retamosa, Laura Amanda Boos, Christian Doerig, Gabriele Gut, Nicola Miglino, Luis Fábregas Ibáñez, Charlotta Schärfe Fruechtenicht, Nandini Chitale, Martin Zoche, Bernd Bodenmiller, Stephane Chevrier, Alexandra Sophia Eklund, Marta Nowak, Sepehr Rahmani Khajouei, Carmen Galani Berardo, Lukasz Kaczmarek, Karin Bosshard, William Archey, Matthias Bodmer, Chiara Louisa Hempel, Parisa Rahimzadeh, Benedict Gosztonyi, Ulrich Richter, Lorenz Bankel   +27 more
doaj   +1 more source

Multidimensional profiling of drug‐treated cells by Imaging Mass Cytometry

FEBS Open Bio, 2019
In pharmaceutical research, high‐content screening is an integral part of lead candidate development. Measuring drug response in vitro by examining over 40 parameters, including biomarkers, signaling molecules, cell morphological changes, proliferation ...
Alexandre Bouzekri, Amanda Esch, Olga Ornatsky   +2 more
doaj   +1 more source

Deep cell phenotyping and spatial analysis of multiplexed imaging with TRACERx-PHLEX

Nature Communications
The growing scale and dimensionality of multiplexed imaging require reproducible and comprehensive yet user-friendly computational pipelines. TRACERx-PHLEX performs deep learning-based cell segmentation (deep-imcyto), automated cell-type annotation ...
Alastair Magness, Emma Colliver, Katey S. S. Enfield, Claudia Lee, Masako Shimato, Emer Daly, David A. Moore, Monica Sivakumar, Karishma Valand, Dina Levi, Crispin T. Hiley, Philip S. Hobson, Febe van Maldegem, James L. Reading, Sergio A. Quezada, Julian Downward, Erik Sahai, Charles Swanton, Mihaela Angelova   +18 more
doaj   +1 more source

Metal-Labeled Aptamers as Novel Nanoprobes for Imaging Mass Cytometry Analysis

, 2020
Imaging mass cytometry (IMC) is an emerging imaging technology that exploits the multiplexed analysis capabilities of the CyTOF mass cytometer to make spatially resolved measurements for tissue sections.
Xiao Liu (65413), Ting Zhang (102583), Jingqi Dang (8649138), Xianting Ding (4985153), Youyi Yu (1795558), Liping Wang (33601), Shanhe Li (7906595)   +6 more
core   +1 more source