Results 71 to 80 of about 4,996,457 (177)

Automatic Generic Registration of Mass Spectrometry Imaging Data to Histology Using Nonlinear Stochastic Embedding

, 2014
The combination of mass spectrometry imaging and histology has proven a powerful approach for obtaining molecular signatures from specific cells/tissues of interest, whether to identify biomolecular changes associated with specific histopathological ...
Dijkstra, J., McDonnell, L.A., Heeren, Ron M. A., Abdelmoula, W.M., Dijkstra, Jouke, Maaten, L. van der, Heeren, R.M.A., Lelieveldt, Boudewijn P. F., Abdelmoula, Walid M., Morreau, Hans, Lelieveldt, B.P.F., Skraskova, Karolina, Tolner, Else A., Skraskova, K., Morreau, H., van der Maaten, Laurens, Carreira, R.J., Balluff, B., Tolner, E.A., Maagdenberg, A.M.J.M. van den, van den Maagdenberg, Arn M. J. M., Balluff, Benjamin, McDonnell, Liam A., Carreira, Ricardo J.   +23 more
core   +1 more source

From surfing to diving into the tumor microenvironment through multiparametric imaging mass cytometry

Frontiers in Immunology
The tumor microenvironment (TME) is a complex ecosystem where malignant and non-malignant cells cooperate and interact determining cancer progression. Cell abundance, phenotype and localization within the TME vary over tumor development and in response ...
Marco Erreni, Marco Erreni, Maria Rita Fumagalli, Matteo Marozzi, Roberto Leone, Raffaella Parente, Raffaella D’Anna, Andrea Doni   +7 more
doaj   +1 more source

Imaging Mass Cytometric Analysis of Postmortem Tissues Reveals Dysregulated Immune Cell and Cytokine Responses in Multiple Organs of COVID-19 Patients

Frontiers in Microbiology, 2020
SARS-coronavirus-2–induced immune dysregulation and inflammatory responses are involved in the pathogenesis of coronavirus disease-2019 (COVID-19). However, very little is known about immune cell and cytokine alterations in specific organs of COVID-19 ...
Chong Wang, Chong Wang, Jiqian Xu, Shaoyuan Wang, Shangwen Pan, Jiancheng Zhang, Yang Han, Yang Han, Yang Han, Muhan Huang, Muhan Huang, Di Wu, Di Wu, Qingyu Yang, Xiaobo Yang, Yang Yang, Ting Shu, Ting Shu, Xiaojing Zou, Ruiting Li, Yufeng Luo, Runqing Yao, Yaxin Wang, Yang Qiu, Yang Qiu, Yu Wang, Ding-Yu Zhang, Qun Yao, Yongpan Yan, Xi Zhou, Xi Zhou, Xi Zhou, You Shang, You Shang, You Shang   +34 more
doaj   +1 more source

Development of 42 marker panel for in-depth study of cancer associated fibroblast niches in breast cancer using imaging mass cytometry

Frontiers in Immunology
Imaging Mass Cytometry (IMC) is a novel, and formidable high multiplexing imaging method emerging as a promising tool for in-depth studying of tissue architecture and intercellular communications. Several studies have reported various IMC antibody panels
Hanna Røgenes, Kenneth Finne, Ingeborg Winge, Lars A. Akslen, Lars A. Akslen, Arne Östman, Arne Östman, Vladan Milosevic   +7 more
doaj   +1 more source

Colorectal Precancerous Lesions: Molecular Mechanisms, Research Tools, and Natural Product‐Based Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
This article systematically elucidates the molecular mechanisms of colorectal precancerous lesions, introduces cutting‐edge research tools like multi‐omics and organoids, and highlights the potential and prospects of natural products such as berberine, resveratrol, and curcumin in preventing and intervening in colorectal carcinogenesis by modulating ...
Shunji Liu, Chujuan Cui, Lingdong Kong, Qiang Xu, Haibo Cheng, Lisha Zhou, Yang Sun   +6 more
wiley   +1 more source

Imaging Mass Cytometry: p173

, 2020
Imaging Mass Cytometry: p173 Raw acquisitions for the paper: A quantitative analysis of the interplay of environment, neighborhood, and cell state in 3D spheroids Vito RT Zanotelli Matthias Leutenegger Xiao‐Kang Lun Fanny Georgi ...
Vito RT Zanotelli, Bernd Bodenmiller
core   +1 more source

Opposing Association of Lung Neutrophils and PD‐L1+ Monocytes in Age‐Related Severity of SARS‐CoV‐2 Infection

Aging Cell, Volume 25, Issue 6, June 2026.
Aging skews pulmonary myeloid responses during acute SARS‐CoV‐2 infection toward severe disease. Disease progression is characterized by excessive lung neutrophil accumulation together with impaired activation of classical monocytes, including a defect in PD‐L1 upregulation.
Serban Morosan, Clémence Granier, Noëlline Guillou, Selma Bennacer, Eléonore Weber‐Delacroix, Julianne Peronnet, François Lanthiez, Sandrine Barthelemy, Christelle Enond, Jean‐Luc Diehl, Elena Paillaud, Carine El‐Sissy, Anne‐Geneviève Marcelin, Vincent Calvez, Stéphane Marot, Amélie Guihot, Christophe Parizot, Karim Dorgham, Guy Gorochov, Christophe Combadière, Alexandre Boissonnas   +20 more
wiley   +1 more source

Imaging Mass Cytometry: p165

, 2020
Imaging Mass Cytometry: p165 Raw acquisitions for the paper: A quantitative analysis of the interplay of environment, neighborhood, and cell state in 3D spheroids Vito RT Zanotelli Matthias Leutenegger Xiao‐Kang Lun Fanny Georgi ...
Vito RT Zanotelli, Bernd Bodenmiller
core   +1 more source

Mass spectrometry imaging using cytometry by time-of-flight strategies for brain tissues: a literature review [PDF]

, 2022
Mass spectrometry (MS) as an analytical approach could provide comprehensive identification and quantitation of the biomolecules (proteins, peptides, nucleic acids, lipids) in a cell, tissue, or organism, from biomarker discovery to prediction of ...
Akbari, Behnaz
core   +1 more source

Multi-modal image analysis for large-scale cancer tissue studies within IMMUcan

Cell Reports: Methods
Summary: In cancer research, multiplexed imaging allows detailed characterization of the tumor microenvironment (TME) and its link to patient prognosis. The integrated immunoprofiling of large adaptive cancer patient cohorts (IMMUcan) consortium collects
Nils Eling, Julien Dorier, Sylvie Rusakiewicz, Robin Liechti, Preethi Devanand, Michelle Daniel, Jonas Windhager, Bruno Palau Fernandez, Sophie Déglise, Lucie Despland, Abdelkader Benyagoub, Marcin Możejko, Dawid Uchal, Ewa Szczurek, Alexander Loboda, Daaf Sandkuijl, Nikesh Parsotam, Henoch S. Hong, Marie Morfouace, Nicolas Guex, George Coukos, Bernd Bodenmiller, Stephanie Tissot, Daniel Schulz   +23 more
doaj   +1 more source