Results 11 to 20 of about 4,996,457 (177)

MATISSE: a method for improved single cell segmentation in imaging mass cytometry [PDF]

BMC Biology, 2021
Background Visualizing and quantifying cellular heterogeneity is of central importance to study tissue complexity, development, and physiology and has a vital role in understanding pathologies.
Matthijs J. D. Baars, Neeraj Sinha, Mojtaba Amini, Annelies Pieterman-Bos, Stephanie van Dam, Maroussia M. P. Ganpat, Miangela M. Laclé, Bas Oldenburg, Yvonne Vercoulen   +8 more
doaj   +2 more sources

Methods for analyzing tellurium imaging mass cytometry data.

PLoS ONE, 2019
Imaging mass cytometry (IMC) is a technique allowing visualization and quantification of over 40 biological parameters in a single experiment with subcellular spatial resolution, however most IMC experiments are limited to endpoint analysis with ...
Jay Bassan, Mark Nitz
doaj   +2 more sources

OMIP-088: Twenty-target imaging mass cytometry panel for major cell populations in mouse formalin fixed paraffin embedded liver. [PDF]

, 2023
The purpose of this 20-target imaging mass cytometry (IMC) panel is to identify the main cell types in formalin fixed paraffin embedded (FFPE) mouse liver tissue with the Hyperion™ mass cytometer from Standard BioTools (formerly Fluidigm).
Stroka, Deborah, Birrer, Fabienne, Fabienne Birrer, Tess Brodie, Deborah Stroka, Brodie, Tess   +5 more
core   +1 more source

Mapping Immunity With Cutting-Edge Spatial Biology and Tissue Cytometry Innovations. [PDF]

MedComm (2020)
This review explores how spatial biology integrates multiplexed imaging and tissue cytometry to reveal immune organization within native tissue contexts. ABSTRACT The immune system operates within organized tissue landscapes, where spatial relationships between cells shape the nature and outcome of immune responses.
Cárdenas-Piedra L, Samuel SG, Mungenast F, Yasothkumar D, Ecker RC, Batra J.   +5 more
europepmc   +2 more sources

Using Imaging Mass Cytometry to Define Cell Identities and Interactions in Human Tissues

Frontiers in Physiology, 2021
In the evolving landscape of highly multiplexed imaging techniques that can be applied to study complex cellular microenvironments, this review characterizes the use of imaging mass cytometry (IMC) to study the human kidney.
Vijayakumar R. Kakade, Marlene Weiss, Lloyd G. Cantley   +2 more
doaj   +1 more source

Advances in mass cytometry and its applicability to digital pathology in clinical-translational cancer research

Advances in Laboratory Medicine, 2021
The development and subsequent adaptation of mass cytometry for the histological analysis of tissue sections has allowed the simultaneous spatial characterization of multiple components.
Cereceda Karina, Jorquera Roddy, Villarroel-Espíndola Franz   +2 more
doaj   +1 more source

Mass Cytometric Analysis of Early-Stage Mycosis Fungoides

Cells, 2022
Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma. Early-stage disease is characterized by superficial infiltrates of small- to medium-sized atypical epidermotropic T lymphocytes that are clonal related.
Nannan Guo, Li Jia, Coby Out-Luiting, Noel F. C. C. de Miranda, Rein Willemze, Frits Koning, Maarten Vermeer, Koen Quint   +7 more
doaj   +1 more source

MATISSE: An analysis protocol for combining imaging mass cytometry with fluorescence microscopy to generate single-cell data

STAR Protocols, 2022
Summary: Exploring tissue heterogeneity on a single-cell level by imaging mass cytometry (IMC) remains challenging because of its limiting resolution. We previously demonstrated that combining higher resolution fluorescence with IMC data in the analysis ...
Daniëlle Krijgsman, Neeraj Sinha, Matthijs J.D. Baars, Stephanie van Dam, Mojtaba Amini, Yvonne Vercoulen   +5 more
doaj   +1 more source

DataSheet_1_Performance of spectral flow cytometry and mass cytometry for the study of innate myeloid cell populations.docx [PDF]

, 2023
IntroductionMonitoring of innate myeloid cells (IMC) is broadly applied in basic and translational research, as well as in diagnostic patient care.
Kassem, Sara, Kyra van der Pan (13796077), Khatri, Indu, Brigitta A.E. Naber (15649463), Paula Díez (10052081), Indu Khatri (511338), Jager, Anniek L. de, Suzanne E.T. Comans (15649466), Louis, Alesha, Orfao, Alberto, Dongen, J. J. M. van, Jacques J.M. van Dongen (10153076), Alesha Louis (13796104), Inge F. de Laat (13796089), Alberto Orfao (108164), Hameetman, Marjolijn, Díez, Paula, Cristina Teodosio (143750), Sara Kassem (13796098), Comans, Suzanne, Laat, Inge F. de, Anniek L. de Jager (13796101), Pan, Kyra van der, Naber, Brigitta A. E., Marjolijn Hameetman (6177341), Teodosio, Cristina   +25 more
core   +1 more source

Performance of spectral flow cytometry and mass cytometry for the study of innate myeloid cell populations [PDF]

, 2023
IntroductionMonitoring of innate myeloid cells (IMC) is broadly applied in basic and translational research, as well as in diagnostic patient care.
Kassem, Sara, Khatri, Indu, Alberto Orfao, Cristina Teodosio, Jacques J.M. van Dongen, Jager, Anniek L. de, Brigitta A.E. Naber, Inge F. de Laat, Louis, Alesha, Orfao, Alberto, Dongen, J. J. M. van, Hameetman, Marjolijn, Indu Khatri, Marjolijn Hameetman, Díez, Paula, Alesha Louis, Comans, Suzanne, Anniek L. de Jager, Paula Díez, Laat, Inge F. de, Pan, Kyra van der, Sara Kassem, Kyra van der Pan, Suzanne E.T. Comans, Naber, Brigitta A. E., Teodosio, Cristina   +25 more
core   +1 more source