Results 31 to 40 of about 52,674 (356)

Application of Artificial Neural Networks for Predicting Imidazole Derivatives' Antimicrobial Activity against Enterococcus faecalis [PDF]

open access: yesFarmacja Polska
Artificial neural networks (ANNs) have emerged as a valuable tool in facilitating the design of synthesis and guiding subsequent biological experiments in the systematic exploration for novel antimicrobial agents. In this paper, two multilayer perceptron-
Anna Badura   +4 more
doaj   +1 more source

Allosteric modulation of DNA by small molecules [PDF]

open access: yes, 2009
Many human diseases are caused by dysregulated gene expression. The oversupply of transcription factors may be required for the growth and metastatic behavior of human cancers.
Chenoweth, David M., Dervan, Peter B.
core   +3 more sources

1-Propyl-4(5)-Methylimidazole Isomers for Temperature Swing Solvent Extraction

open access: yesMolecules, 2022
Temperature swing solvent extraction (TSSE) utilizes an amine solvent with temperature-dependent water solubility to dissolve water at a lower temperature to concentrate or crystallize the brine and the phases are separated.
Shuai Qian   +4 more
doaj   +1 more source

Radical Fluoroalkylation Reactions [PDF]

open access: yes, 2018
Recent protocols and reactions for catalytic radical perfluoroalkylations will be described. The production of perfluoroalkyl radicals (RF = CnF2n+1, n ≥ 2), which effect both addition and substitution reactions on organic substrates, can be realized ...
Barata Vallejo, Sebastian   +2 more
core   +1 more source

Magnesium and imidazole propionate

open access: yesClinical Nutrition ESPEN, 2021
Circulating levels of imidazole propionate (ImP), a microbial metabolite of histidine, were higher in participants with type 2 diabetes (T2D) compared to those without and also induced insulin resistance. We hypothesize that low intake of magnesium (Mg) and/or low body Mg status in humans may lead to low Mg concentrations in gut microbiota, and, in ...
Lei Fan   +7 more
openaire   +3 more sources

The Reaction of Aminonitriles with Aminothiols: A Way to Thiol-Containing Peptides and Nitrogen Heterocycles in the Primitive Earth Ocean

open access: yesLife, 2018
The Strecker reaction of aldehydes with ammonia and hydrogen cyanide first leads to α-aminonitriles, which are then hydrolyzed to α-amino acids.
Ibrahim Shalayel   +4 more
doaj   +1 more source

Pyrazoles and imidazoles as ligands. XV. preparation, spectra and magnetic properties of di-μ-hydroxo-bis- [di(2-methylimidazole)copper(II)] diperchlorate dihydrate [PDF]

open access: yes, 1971
The preparation of the title compound is reported from Cu(ClO4)2, 2-methylimidazole and a small amount of water in ethanol solution. The compound consists of dimeric units [(2MIz)2Cu(OH)]22+, to which two perchlorate anions and two molecules of water are
Knetsch, D.   +2 more
core   +2 more sources

An Updated Review on the Synthesis and Antibacterial Activity of Molecular Hybrids and Conjugates Bearing Imidazole Moiety

open access: yesMolecules, 2020
The rapid growth of serious infections caused by antibiotic resistant bacteria, especially the nosocomial ESKAPE pathogens, has been acknowledged by Governments and scientists and is one of the world’s major health problems.
Renzo Rossi, Maurizio Ciofalo
doaj   +1 more source

Pharmacokinetics of imidazole antimycotics [PDF]

open access: yesPostgraduate Medical Journal, 1979
Summary According to data on the imidazole antimycotics at present on the market, none of these products satisfactorily fills the gaps which exist in the treatment for mycoses of internal organs, although they have brought considerable progress in the topical treatment of mycoses.
openaire   +3 more sources

Synthesis and photophysical properties of benzoxazolyl-imidazole and benzothiazolyl-imidazole conjugates

open access: yesRSC Advances, 2021
The effect of heteroatoms on the structural and photophysical properties of donor-π-acceptor molecules, comprising imidazole and benzoxazolyl as well as imidazole and benzothiazolyl units, was investigated.
Hsing-Yu Chen   +5 more
openaire   +3 more sources

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