Results 111 to 120 of about 2,892 (197)

<i>N</i>-Alkyl Derivatives of Deoxynojirimycin (DNJ) as Antiviral Agents: Overview and Update. [PDF]

Molecules
Checconi P, Iacopetta D, Catalano A, Ceramella J, Cavalluzzi MM, Mariconda A, Marsico S, Aquaro S, Longo P, Sinicropi MS, Lentini G.   +10 more
europepmc   +1 more source

Molecular Basis of <i>Pseudomonas syringae</i> pv <i>actinidiae</i> Levansucrase Inhibition by a Multivalent Iminosugar. [PDF]

J Agric Food Chem
Cicchi C, Pazzagli L, Paoli P, Campigli S, Marchi G, Cardona F, Clemente F, Pavone S, Ferraroni M, Canovai A, Matassini C, Luti S.   +11 more
europepmc   +1 more source

Iminosugar derivatives as alfa-glycosidase inhibitors

, 2010
Peer ...
García Fernández, José Manuel, Sánchez-Fernández, Elena M., Ortiz-Mellet, Carmen, Rísquez-Cuadro, Rocio   +3 more
openaire   +1 more source

Guanidinium Iminosugars as Glycosidase Inhibitors

, 2017
Effective drug design to modulate biological processes requires knowledge of how substrates and ligands are recognized by their complementary enzymes and receptors. Glycoside trimming enzymes are crucially important in a broad range of metabolic pathways, including glycoprotein and glycolipid processing and carbohydrate digestion.
openaire   +2 more sources

Biologically active pyrrolidine iminosugars. Stereochemical aspects

, 2014
Pyrrolidine iminosugars, sugar analogs furanoside form with the endocyclic oxygenreplaced by a nitrogen atom, are known as potent inhibitors of glycosidases and of otherglycoprocessing enzymes. Therefore their potential for a variety of medical applications drugsfor metabolic disorders, antiviral and anticancer agents makes them interesting as ...
Hirtopeanu, A., Stavarache, C., Teodorescu, F., Mitan, C., Deleanu, C., Man, I., Tarko, L.   +6 more
openaire   +1 more source

Exploring the Potential of Iminosugars as Antivirals for Crimean-Congo Haemorrhagic Fever Virus, Using the Surrogate Hazara Virus: Liquid-Chromatography-Based Mapping of Viral N-Glycosylation and In Vitro Antiviral Assays. [PDF]

Pathogens, 2023
Tyrrell BE, Kumar A, Gangadharan B, Alonzi D, Brun J, Hill M, Bharucha T, Bosworth A, Graham V, Dowall S, Miller JL, Zitzmann N.   +11 more
europepmc   +1 more source

A new glucocerebrosidase chaperone reduces α-synuclein and glycolipid levels in iPSC-derived dopaminergic neurons from patients with gaucher disease and parkinsonism [PDF]

, 2016
et al,, Fujiwara, Hideji, Ory, Daniel S, Sidhu, Rohini   +3 more
core   +1 more source

Enhancement of iminosugar production, 1-deoxynojirimycin and 1-deoxymannojirimycin, in recombinant <i>Corynebacterium glutamicum</i>. [PDF]

Food Sci Biotechnol
Siziya IN, Lim HJ, Jung DH, Baek S, Lee S, Seo MJ.   +5 more
europepmc   +1 more source

Food Iminosugars and Related Synthetic Derivatives Shift Energy Metabolism and Induce Structural Changes in Colon Cancer Cell Lines. [PDF]

Foods
Montebugnoli T, Grootaert C, Bordoni A, Rajković A, Alderweireldt E, Rombaut J, De Maeseneire SL, Van Camp J, De Mol ML.   +8 more
europepmc   +1 more source

Exploring Multivalent Architectures for Binding and Stabilization of <i>N</i>-Acetylgalactosamine 6-Sulfatase. [PDF]

Molecules
Davighi MG, Clemente F, D'Adamio G, Martínez-Bailén M, Morano A, Goti A, Morrone A, Matassini C, Cardona F.   +8 more
europepmc   +1 more source