Exploring Small-Molecule Inhibitors of Glucosidase II: Advances, Challenges, and Therapeutic Potential in Cancer and Viral Infection. [PDF]
Int J Mol SciOo TZM +5 more
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N-Substituted l-Iminosugars for the Treatment of Sanfilippo Type B Syndrome. [PDF]
J Med Chem, 2023 De Pasquale V +9 more
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[[alternative]]Syntheses of Quercitols, Azepanes and Their Analogues for Glycosidase Inhibitors from D-Quinic Acid [PDF]
計畫編號：NSC93-2113-M032-007研究期間：200408~200507研究經費：782,000[[abstract]]一些具有生化活性的類醣分子（sugar-like）廣泛的存在於天然界。如果其結構是醣 分子環上的氧被置換成氮原子，則被稱為azasugars（或謂iminosugars、azahexases）。這 些分子例如：nojirmycin、1-deoxy-nojirimycin（DNJ），和isofagomine。除此之外，尚有 一些所謂之Carbasugars ...
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Iminosugars of the Invasive Arboreal <i>Amorpha fruticosa</i> and Glycosidase Inhibition Potential. [PDF]
Plants (Basel)Nash RJ +3 more
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Biocatalytic Cascades toward Iminosugar Scaffolds Reveal Promiscuous Activity of Shikimate Dehydrogenases. [PDF]
ACS Cent Sci, 2023 Swanson CRB +4 more
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Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers. [PDF]
J Enzyme Inhib Med Chem, 2023 Vaaland IC +7 more
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Transcriptomic Analysis of Biofilm Formation Inhibition by PDIA Iminosugar in <i>Staphylococcus aureus</i>. [PDF]
Antibiotics (Basel)Tomusiak-Plebanek A +6 more
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Influence of Side Chain Conformation on the Activity of Glycosidase Inhibitors. [PDF]
Angew Chem Int Ed Engl, 2023 Tseng PS, Ande C, Moremen KW, Crich D.
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Evidence of α-Synuclein/Glucocerebrosidase Dual Targeting by Iminosugar Derivatives. [PDF]
ACS Chem NeurosciTagliaferro G +10 more
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