Results 61 to 70 of about 2,579 (147)
Molecular Nutrition &Food Research, Volume 69, Issue 22, November 2025.This study compared the preventive effects of dietary resistant starch (RS2) from maize and d‐fagomine (FG) from buckwheat on cardiometabolic risk factors in high‐fat (HF) diet‐fed rats. Wistar‐Kyoto rats (n = 11–12/group) received STD, HF, HF + RS, or HF + FG diets for 10 weeks.
Bernat Miralles‐Pérez +10 more
wiley +1 more source
Intramolecular [3+2] cycloaddition of azido-unsaturated esters derived of monosaccharides [PDF]
, 2013 Iminosugars have been shown to be very potent inhibitors of glycosidases and glycolsyltransferases. Due to their ability to resemble the transition states of the sugars involved in these processes, a variety of m onocyclic and bicyclic iminosugars have
Calvo-Losada, Saturnino +3 more
core
Developments in Carbohydrate-Based Metzincin Inhibitors
Pharmaceuticals, 2020 Matrix metalloproteinases (MMPs) and A disintegrin and Metalloproteinase (ADAMs) are zinc-dependent endopeptidases belonging to the metzincin superfamily.
Doretta Cuffaro +3 more
doaj +1 more source
Synthesis of Novel 3-Amino(Hydroxy)methyl-l-fuco-Azafagomines as Leads for Selective Inhibitors of α-l-Fucosidases [PDF]
, 2010 The synthesis of 3-substituted l-fuco-azafagomines from d-lyxose is reported. They represent the first example of aza-C-glycosides having a biimino (-NH-NH-) moiety.
Carmona Asenjo, Ana Teresa +4 more
core +1 more source
A Fullerene‐Based Selenosugar Ball
European Journal of Organic Chemistry, Volume 28, Issue 36, September 29, 2025.A fullerene hexakis‐adduct decorated with 12 peripheral seleno‐d‐talitol moieties is synthesized efficiently with a Th‐symmetry from a hexakis‐adduct of [60]fullerene prepared by a cycloaddition reaction and subsequent copper‐catalyzed azide‐alkyne cycloaddition click chemistry.
Reinier Lemos +8 more
wiley +1 more source
Molecules, 2013 D-Glucopyranose-derived and L-idopyranose-derived piperidine nitrones were synthesized in good overall yields through six-step reaction sequence starting from readily available 2,3,4,6-tetra-O-benzyl-D-glucopyranose.
Chu-Yi Yu +4 more
doaj +1 more source
Molecules, 2020 Pharmacological chaperones (PCs) are small compounds able to rescue the activity of mutated lysosomal enzymes when used at subinhibitory concentrations.
Maria Giulia Davighi +6 more
doaj +1 more source
Health Science Reports, Volume 8, Issue 7, July 2025.ABSTRACT Background and Aims Despite widespread use, more research is needed to assess the health effects of herbal plants. Preliminary research indicates that cucumber extract (Cucumis sativus L.) is safe and may exhibit analgesic properties for joint pain, but studies on its impact on other health‐related outcomes—including mood, sleep, and health ...
Heather A. Hausenblas +2 more
wiley +1 more source
A Biocatalytic Cascade for the Valorization of Sugars
ChemCatChem, Volume 17, Issue 12, June 23, 2025.We report a one‐pot, three‐step biocatalytic cascade to synthesize trihydroxy‐piperidine and ‐azepane iminosugars directly from monosaccharides, employing transaminase (ATA) and galactose oxidase (GOase) enzymes. Abstract Biocatalytic cascades offer products of multistep synthesis without the use of protecting groups or isolation of intermediates. This
Kathryn Yeow +4 more
wiley +1 more source
Synthesis of lipophilic 1-deoxygalactonojirimycin derivatives as D-galactosidase inhibitors
Beilstein Journal of Organic Chemistry, 2010 N-Alkylation at the ring nitrogen of the D-galactosidase inhibitor 1-deoxygalactonojirimycin with a functionalised C6 alkyl chain followed by modification with different aromatic substituents provided lipophilic 1-deoxygalactonojirimycin derivatives ...
Georg Schitter +13 more
doaj +1 more source