Results 81 to 90 of about 8,040 (174)

Three-Dimensional Modeling of Camelus dromedarius T Cell Receptor Gamma (TRG)_Delta (TRD)/CD1D Complex Reveals Different Binding Interactions Depending on the TRD CDR3 Length

Antibodies
Background: In the adaptive immune response of the dromedary (Camelus dromedarius, Camdro), the T cell receptor (TR) repertoire of the gamma–delta (γδ) T cells is unusually diversified both by somatic hypermutation in rearranged TR gamma (TRG) and delta (
Salvatrice Ciccarese, Marie-Paule Lefranc, Giulia C. M. Perrone, Pietro D’Addabbo, Ciro Leonardo Pierri   +4 more
doaj   +1 more source

Assessment of variation in B-cell receptor heavy chain repertoire in patients with end-stage renal disease by high-throughput sequencing

Renal Failure, 2019
Background/Aims: End-stage renal disease (ESRD), characterized by progressive loss of rental function during the disease course, has been reported to be correlated with immune dysregulation.
Lei Wang, Yong Dai, Song Liu, Liusheng Lai, Qiang Yan, Huaizhou Chen, Jiaxing Zhang, Weiguo Sui   +7 more
doaj   +1 more source

Development of ferret immune repertoire reference resources and single-cell-based high-throughput profiling assays

Journal of Virology
Domestic ferrets (Mustela putorius furo) are important for modeling human respiratory diseases. However, ferret B and T cell receptors have not been completely identified or annotated, limiting immune repertoire studies.
Evan S. Walsh, Kui Yang, Tammy S. Tollison, Sujatha Seenu, Nicole Adams, Guilhem Zeitoun, Ifigeneia Sideri, Geraldine Folch, Hayden N. Brochu, Hsuan Chou, Sofia Kossida, Ian A. York, Xinxia Peng   +12 more
doaj   +1 more source

From IMGT-ONTOLOGY DESCRIPTION Axiom to IMGT Standardized Labels: For Immunoglobulin (IG) and T Cell Receptor (TR) Sequences and Structures

, 2011
INTRODUCTIONMore than 560 IMGT standardized labels have been defined for the description of immunoglobulin (IG) and T cell receptor (TR) sequences and structures.
Marie-Paule Lefranc, Lefranc, Mp
core   +1 more source

Standardized Sequence and Structure Analysis of Antibody Using IMGT®

, 2010
International audienceStandardized sequence and structure analysis of antibody using IMGT®, the international ImMunoGeneTics information system® (http://www.imgt.org), allows to bridge, for the first time, the gap between antibody sequences and three ...
Marie-Paule Lefranc, Duroux, Patrice, Ehrenmann, François, Patrice Duroux, François Ehrenmann, Giudicelli, Véronique, Véronique Giudicelli, Lefranc, Marie-Paule   +7 more
core   +1 more source

Use of IMGT® Databases and Tools for Antibody Engineering and Humanization

, 2018
International audienceIMGT®, the international ImMunoGeneTics information system® ( http://www.imgt.org ), was created in 1989 by Marie-Paule Lefranc (Université de Montpellier and CNRS) to manage the huge diversity of the antigen receptors ...
Marie-Paule Lefranc, Duroux, Patrice, Ehrenmann, François, Patrice Duroux, François Ehrenmann, Giudicelli, Véronique, Véronique Giudicelli, Lefranc, Marie-Paule, Sofia Kossida, Kossida, Sofia   +9 more
core   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

IMGT/3Dstructure-DB: Querying the IMGT Database for 3D Structures in Immunology and Immunoinformatics (IG or Antibodies, TR, MH, RPI, and FPIA)

, 2011
INTRODUCTIONIMGT/3Dstructure-DB is the three-dimensional (3D) structure database of IMGT, the international ImMunoGenetics information system that is acknowledged as the global reference in immunogenetics and immunoinformatics.
Marie-Paule Lefranc, Ehrenmann, François, Lefranc, Mp, François Ehrenmann   +3 more
core   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

From benchmarking alignment of genome assemblies to IMGT annotation: the paradigm of the bovine Bos taurus T cell receptor (TRG) locus

BMC Genomics
T cell receptors (TR) are essential components of the adaptive immune system, typically classified into αβ and γδ types. In humans and mice, αβ T cells predominate, with γδ T cells comprising only a small percentage of the total T cell population.
Hao Zhou, Chimari Jiko, Christoph Gerle, Marie-Paule Lefranc, Kazutaka Katoh, Daron M. Standley   +5 more
doaj   +1 more source