Results 11 to 20 of about 4,210 (150)
Immunothrombosis and its underlying biological mechanisms
Hematology, Transfusion and Cell TherapyThe evolutionary conserved link between coagulation and innate immunity is a biological process characterized by the thrombosis formation stimulus of immune cells and specific thrombosis-related molecules.
Giovanna Degasperi +2 more
exaly +4 more sources
Extracellular DNA—A Danger Signal Triggering Immunothrombosis [PDF]
Frontiers in Immunology, 2020 Clotting and inflammation are effective danger response patterns positively selected by evolution to limit fatal bleeding and pathogen invasion upon traumatic injuries.
Chongxu Shi +3 more
doaj +2 more sources
The Role of Glutathione in Prevention of COVID-19 Immunothrombosis: A Review
Frontiers in Bioscience-Landmark, 2023 Immunothrombosis has emerged as a dominant pathological process exacerbating morbidity and mortality in acute- and long-COVID-19 infections. The hypercoagulable state is due in part to immune system dysregulation, inflammation and endothelial cell damage,
Ira Glassman +10 more
doaj +3 more sources
Staphylococcus aureus Endocarditis Immunothrombosis
MetabolitesBackground: Infective endocarditis continues to represent a challenge for healthcare systems, requiring careful management and resources. Recent studies have indicated a shift in the predominant pathogens of concern, with Streptococcus sp.
Francesco Nappi
doaj +2 more sources
Role of defensins in immunothrombosis
Rheumatology &Autoimmunity, Volume 6, Issue 3, Page 138-148, September 2026.Defensins are important proteins that link the immune system and blood clotting, playing a key role in immunothrombosis. α‐defensins mainly come from neutrophils, while β‐defensins are produced by epithelial cells and platelets. These proteins help form blood clots in several ways: they slow down clot breakdown (fibrinolysis), activate platelets, and ...
Yuebing Wang +7 more
wiley +2 more sources
COVID-19, immunothrombosis and venous thromboembolism:biological mechanisms [PDF]
, 2021 Thrombotic events that frequently occur in COVID-19 are predominantly venous thromboemboli (VTE) and are associated with increasing disease severity and worse clinical outcomes.
Loo, Joan +2 more
core +1 more source
COVID-19: Lung-Centric Immunothrombosis
Frontiers in Cellular and Infection Microbiology, 2021 The respiratory tract is the major site of infection by SARS-CoV-2, the virus causing COVID-19. The pulmonary infection can lead to acute respiratory distress syndrome (ARDS) and ultimately, death.
Peter R. Kvietys +5 more
doaj +1 more source
Advances in our understanding of anti-PF4 related immunothrombosis [PDF]
Frontiers in ImmunologyLinda Schönborn +2 more
exaly +2 more sources
Frontiers in Cell and Developmental Biology, 2022 Activated platelets and platelet-derived extracellular vesicles (EVs) have emerged as central players in thromboembolic complications associated with severe coronavirus disease 2019 (COVID-19).
Marie Ebeyer-Masotta +4 more
doaj +1 more source
Diagnostics, 2023 Immunothrombosis, an excessive inflammatory response with simultaneous overactivation of the coagulation system, is a central pathomechanism in sepsis and COVID-19. It is associated with cellular activation, vascular damage, and microvascular thrombosis,
Tanja Eichhorn +12 more
doaj +1 more source