Results 61 to 70 of about 4,210 (150)

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, Volume 40, Issue 16, August 2026.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source

The Role of Inflammation and Immunity in Cardiovascular Disease: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong, Zhen Wang, Xiaoxiao Lin, Ziwen Lei, Qianqian Huang, Hang Liu, Fei Luan, Junbo Zou, Yajun Shi   +8 more
wiley   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, Volume 81, Issue 8, Page 2675-2712, August 2026.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Platelets in infection: intrinsic roles and functional outcomes

Frontiers in Immunology
Platelets have long been acknowledged for their essential roles in hemostasis and thrombosis; however, recent insights highlight their broader involvement as key participants in host responses during infection. Beyond their classical functions, platelets
Yuwei Hu, Yuwei Hu, Shuchang Dai, Shuchang Dai, Congchao Qiao, Congchao Qiao, Congchao Qiao, Yifan Ye, Junyi Ren, Kai Wang, Kai Wang, Ling Li, Ling Li, Zhong Liu, Zhong Liu   +14 more
doaj   +1 more source

Neutrophil extracellular traps induced by activated platelets as a cause of neutrophil–platelet aggregation in β‐thalassaemia/haemoglobin E patients

British Journal of Haematology, Volume 209, Issue 2, Page 703-717, August 2026.
Abnormal neutrophils and platelets in splenectomised β‐thalassaemia/haemoglobin E (HbE) disease contribute to neutrophil–platelet aggregation, leading to a high risk of thrombus formation. Activated platelets induce neutrophils to generate neutrophil extracellular trap (NETs) via the P‐selectin–P‐selectin glycoprotein ligand‐1 (PSGL1) pathway, which ...
Rattanawan Thubthed, Rattanaporn Praneetponkang, Potchaman Sittipaisankul, Chayada Thiengtavor, Suwathida Chumpuchanaphai, Kittiphong Paiboonsukwong, Suthat Fucharoen, Kovit Pattanapanyasat, Jim Vadolas, Duncan R. Smith, Saovaros Svasti, Pornthip Chaichompoo   +11 more
wiley   +1 more source

Host Defense Antimicrobial Peptides (HDPs) as Regulators of Hemostasis and Vascular Biology

Biomolecules
Host defense peptides (HDPs), ancestral effectors of innate immunity, have emerged as pleiotropic regulators transcending their antimicrobial origins. This review critically examines the complex interplay among HDPs, hemostasis, and tissue repair.
Sergio Roberto Aguilar-Ruiz, Francisco Javier Sánchez-Peña, Héctor Maximino Rodríguez-Magadán, Miguel Angel Domínguez-Martínez, Héctor Ulises Bernardino-Hernández, Alba Soledad Aquino-Domínguez   +5 more
doaj   +1 more source

Thromboinflammation in dogs with virulent babesiosis

Frontiers in Veterinary Science
IntroductionBabesia rossi infection in dogs is associated with severe hemostatic dysregulation and systemic inflammation. The close interplay between innate immunity and coagulation in pathological states, including acute infections, may lead to thrombus
Amelia Goddard, Johan P. Schoeman, Andrew L. Leisewitz, Andrew L. Leisewitz, Peter N. Thompson, Annemarie T. Kristensen   +5 more
doaj   +1 more source

The risk of venous thromboembolism in kidney transplant recipients is enhanced following a cytomegalovirus infection

Frontiers in Immunology
IntroductionIn immunocompetent individuals, past CMV infection has been linked to venous thromboembolism (VTE) risk, but evidence remains inconclusive due to timing of serologic diagnosis. Data in immunocompromised patients are scarce.
Christophe Masset, Christophe Masset, Marine Lorent, Florent Le Borgne, Anne Scemla, Clarisse Kerleau, Celine Bressollette-Bodin, Emmanuel Morelon, Xavier Charmetant, Moglie Lequintrec-Donnette, Vincent Pernin, Marc Ladrière, Sophie Girerd, Olivier Aubert, Christophe Legendre, Antoine Sicard, Laetitia Albano, Carmen Lefaucheur, Gillian Divard, Christophe Mariat, Guillaume Claisse, Jacques Dantal, Jacques Dantal, Magali Giral, Magali Giral   +24 more
doaj   +1 more source

Role of Thromboelastometry in Sepsis-Induced Coagulopathy: A Narrative Review

Medical Sciences
Sepsis-induced coagulopathy (SIC) represents an early, predominantly prothrombotic disturbance that is difficult to detect using conventional coagulation tests.
Andrzej Lubiewski, Mariusz Siemiński
doaj   +1 more source

Intracellular communication and immunothrombosis in sepsis

, 2022
Inflammation and coagulation are the critical responses to infection that include leukocytes, platelets, and vascular endothelial cells responding in concert to eradicate the invading pathogen.
Iba, Toshiaki, Levi, Marcel, Levy, Jerrold H.   +2 more
core   +1 more source