Development of the membrane ceiling method for in vitro spermatogenesis [PDF]
Scientific ReportsSpermatogenesis is one of the most complex processes of cell differentiation and its failure is a major cause of male infertility. Therefore, a proper model that recapitulates spermatogenesis in vitro has been long sought out for basic and clinical ...
Maki Kamoshita +11 more
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Understanding the Underlying Molecular Mechanisms of Meiotic Arrest during In Vitro Spermatogenesis in Rat Prepubertal Testicular Tissue [PDF]
International Journal of Molecular Sciences, 2022 Ludovic Dumont +2 more
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Spermatogonial Stem Cells for In Vitro Spermatogenesis and In Vivo Restoration of Fertility [PDF]
Cells, 2020 Fahar Ibtisham, Ali Honaramooz
exaly +2 more sources
Artificial Gametogenesis and In Vitro Spermatogenesis: Emerging Strategies for the Treatment of Male Infertility [PDF]
International Journal of Molecular SciencesAthanasios Zachariou +2 more
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Roles of Spermatogonial Stem Cells in Spermatogenesis and Fertility Restoration
Frontiers in Endocrinology, 2022 Spermatogonial stem cells (SSCs) are a group of adult stem cells in the testis that serve as the foundation of continuous spermatogenesis and male fertility.
Lei Diao +5 more
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Transplantation of mouse iPSCs into testis of azoospermic mouse model: in vivo and in vitro study
Artificial Cells, Nanomedicine, and Biotechnology, 2019 This study aimed to induce spermatogenesis in azoospermic testis through induced pluripotent stem cells (iPSCs) derived spermatogonial stem cell-like cells (SSCLCs) after iPSCs in vivo and in vitro transplantation and three-dimensional organ culture. DiI-
Forouzan Rahmani +3 more
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eLife, 2023 Children undergoing cancer treatments are at risk for impaired fertility. Cryopreserved prepubertal testicular biopsies could theoretically be later matured in vitro to produce spermatozoa for assisted reproductive technology.
Laura Moutard +14 more
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Spermatogonial stem cells: Progress and prospects
Asian Journal of Andrology, 2015 Twenty years ago, the transplantation of spermatogonial stem cells (SSCs) from a mouse to other recipient mice was shown to be feasible, which clearly demonstrated the functional identity of SSCs.
Mitsuru Komeya, Takehiko Ogawa
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Time-course microarray transcriptome data of in vitro cultured testes and age-matched in vivo testes
Data in Brief, 2020 In vitro spermatogenesis, which produces fertile spermatozoa, has been successfully performed using an organ culture method from murine tissue. Here, we provide a dataset of time-course microarray transcriptome data of in vitro cultured neonate murine ...
Takeru Abe +5 more
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LncRNA5251 inhibits spermatogenesis via modification of cell-cell junctions
Biology Direct, 2023 Background Male factors-caused decline in total fertility has raised significant concern worldwide. LncRNAs have been identified to play various roles in biological systems, including spermatogenesis. This study aimed to explore the role of lncRNA5251 in
Cong Zhang +11 more
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