Results 21 to 30 of about 51,909 (235)

Understanding the Underlying Molecular Mechanisms of Meiotic Arrest during In Vitro Spermatogenesis in Rat Prepubertal Testicular Tissue [PDF]

International Journal of Molecular Sciences, 2022
Justine Saulnier, Frédéric Chalmel, Marion Delessard   +2 more
exaly   +2 more sources

Spermatogonial Stem Cells for In Vitro Spermatogenesis and In Vivo Restoration of Fertility [PDF]

Cells, 2020
Fahar Ibtisham, Ali Honaramooz
exaly   +2 more sources

Artificial Gametogenesis and In Vitro Spermatogenesis: Emerging Strategies for the Treatment of Male Infertility [PDF]

International Journal of Molecular Sciences
Aris Kaltsas, Maria-Anna Kyrgiafini, Zissis Mamuris   +2 more
exaly   +2 more sources

Models of in vitro spermatogenesis [PDF]

Spermatogenesis, 2012
Understanding the mechanisms that lead to the differentiation of male germ cells from their spermatogonial stem cells through meiosis to give rise to mature haploid spermatozoa has been a major quest for many decades. Unlike most other cell types this differentiation process is more or less completely dependent upon the cells being located within the ...
Hunter, D., Anand Ivell, R., Danner, S., Ivell, R.   +3 more
openaire   +3 more sources

Roles of Spermatogonial Stem Cells in Spermatogenesis and Fertility Restoration

Frontiers in Endocrinology, 2022
Spermatogonial stem cells (SSCs) are a group of adult stem cells in the testis that serve as the foundation of continuous spermatogenesis and male fertility.
Lei Diao, Paul J. Turek, Constance M. John, Fang Fang, Renee A. Reijo Pera, Renee A. Reijo Pera   +5 more
doaj   +1 more source

Steroidogenesis and androgen/estrogen signaling pathways are altered in in vitro matured testicular tissues of prepubertal mice

eLife, 2023
Children undergoing cancer treatments are at risk for impaired fertility. Cryopreserved prepubertal testicular biopsies could theoretically be later matured in vitro to produce spermatozoa for assisted reproductive technology.
Laura Moutard, Caroline Goudin, Catherine Jaeger, Céline Duparc, Estelle Louiset, Tony Pereira, François Fraissinet, Marion Delessard, Justine Saulnier, Aurélie Rives-Feraille, Christelle Delalande, Hervé Lefebvre, Nathalie Rives, Ludovic Dumont, Christine Rondanino   +14 more
doaj   +1 more source

Transplantation of mouse iPSCs into testis of azoospermic mouse model: in vivo and in vitro study

Artificial Cells, Nanomedicine, and Biotechnology, 2019
This study aimed to induce spermatogenesis in azoospermic testis through induced pluripotent stem cells (iPSCs) derived spermatogonial stem cell-like cells (SSCLCs) after iPSCs in vivo and in vitro transplantation and three-dimensional organ culture. DiI-
Forouzan Rahmani, Mansoureh Movahedin, Zohreh Mazaheri, Masoud Soleimani   +3 more
doaj   +1 more source

Methylation of the Gpat2 promoter regulates transient expression during mouse spermatogenesis [PDF]

, 2015
Spermatogenesis is a highly regulated process that involves both mitotic and meiotic divisions, as well as cellular differentiation to yield mature spermatozoa from undifferentiated germinal stem cells.
Cattaneo, Elizabeth Renee, Coleman, Rosalind A., Garcia Fabiani, Maria Belen, Gonzalez-Baró, Lacunza, Ezequiel, Montanaro, Mauro Aldo, Pellon Maison, Magali   +6 more
core   +2 more sources

Throughout in vitro first spermatogenic wave: Next-generation sequencing gene expression patterns of fresh and cryopreserved prepubertal mice testicular tissue explants

Frontiers in Endocrinology, 2023
IntroductionSuitable cryopreservation procedures of pre-pubertal testicular tissue associated with efficient culture conditions are crucial in the fields of fertility preservation and restoration.
Ludovic Dumont, Ludovic Dumont, Hélène Lopez Maestre, Hélène Lopez Maestre, Frédéric Chalmel, Louise Huber, Louise Huber, Aurélie Rives-Feraille, Aurélie Rives-Feraille, Laura Moutard, Laura Moutard, Frédérique Bateux, Frédérique Bateux, Christine Rondanino, Christine Rondanino, Nathalie Rives, Nathalie Rives, Nathalie Rives   +17 more
doaj   +1 more source

Spermatogonial stem cells: Progress and prospects

Asian Journal of Andrology, 2015
Twenty years ago, the transplantation of spermatogonial stem cells (SSCs) from a mouse to other recipient mice was shown to be feasible, which clearly demonstrated the functional identity of SSCs.
Mitsuru Komeya, Takehiko Ogawa
doaj   +1 more source