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Be aware, innate immune cells remember [PDF]
Aging, 2018 Contains fulltext : 199946.pdf (Publisher’s version ) (Open Access)
Riksen, N.P., Netea, M.G., Netea, M.G.
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Frontiers in Microbiology, 2012 Invasive aspergillosis is a significant threat to health and is a major cause of mortality in immunocompromised individuals. Understanding the interaction between the fungus and the immune system is important in determining how the immunocompetent host ...
Charles Oliver Morton +3 more
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Targeting Innate Immunity to Enhance the Efficacy of Radiation Therapy
Frontiers in Immunology, 2019 Radiation continues to play a major role in the treatment of almost every cancer type. Traditional radiation studies focused on its ability to damage DNA, but recent evidence has demonstrated that a key mechanism driving the efficacy of radiation in vivo
Tahir B. Dar +3 more
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Emerging Concepts in Innate Lymphoid Cells, Memory, and Reproduction
Frontiers in Immunology, 2022 Members of the innate immune system, innate lymphoid cells (ILCs), encompass five major populations (Natural Killer (NK) cells, ILC1s, ILC2s, ILC3s, and lymphoid tissue inducer cells) whose functions include defense against pathogens, surveillance of ...
Rodolfo R. Favaro +4 more
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Immunomodulation of Innate Immune Cells
, 2020 Activation of innate immune system underlies both pathological and physiological inflammatory responses and is critical for the host. Regulated innate immune response is thus essential not only for the elimination of invading pathogens but also for the ...
core +1 more source
Innate Immune Cells Speak Manganese [PDF]
Immunity, 2018 Some metal ions, such as Ca2+ and Zn2+, are involved in intracellular communication in immune cells by acting as second messengers. In this issue of Immunity, Wang et al. (2018) present findings implying a similar role for an additional metal ion, by showing that manganese participates in the recognition of cytoplasmic DNA.
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Role of Innate Immune Cells in the Control of Influenza A Virus Infection
Al-SalamJournal for Medical ScienceIn human immune response against invading viruses, the innate immune system plays a critical role in the early defense towards variable viral infections before the adaptive immune response triggered, particularly against influenza viruses, like with ...
Marwa Lafta Jabur +2 more
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CD90+ stromal cells are non-professional innate immune effectors of the human colonic mucosa
Frontiers in Immunology, 2013 Immune responses at the intestinal mucosa must allow for host protection whilst simultaneously avoiding inappropriate inflammation. Although much work has focused on the innate immune functionality of hematopoietic immune cells, non-hematopoietic cell ...
Benjamin M J Owens +8 more
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Innate immunity and early liver inflammation
Frontiers in Immunology, 2023 The innate system constitutes a first-line defence mechanism against pathogens. 80% of the blood supply entering the human liver arrives from the splanchnic circulation through the portal vein, so it is constantly exposed to immunologically active ...
Jordi Yang Zhou, Jordi Yang Zhou
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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