Results 41 to 50 of about 5,833,650 (299)

Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells

Journal of Immunology Research, 2015
Tuberculosis (TB) remains a serious global public health problem that results in up to 2 million deaths each year. TB is caused by the human pathogen, Mycobacterium tuberculosis (Mtb), which infects primarily innate immune cells patrolling the lung ...
Jonathan Kevin Sia, Maria Georgieva, Jyothi Rengarajan   +2 more
doaj   +1 more source

Modeling Oncolytic Viral Therapy, Immune Checkpoint Inhibition, and the Complex Dynamics of Innate and Adaptive Immunity in Glioblastoma Treatment

Frontiers in Physiology, 2020
Oncolytic viruses are of growing interest to cancer researchers and clinicians, due to their selectivity for tumor cells over healthy cells and their immunostimulatory properties.
Kathleen M. Storey, Sean E. Lawler, Trachette L. Jackson   +2 more
doaj   +1 more source

Innate sensing of HIV-infected cells [PDF]

, 2011
Cell-free HIV-1 virions are poor stimulators of type I interferon (IFN) production. We examined here how HIV-infected cells are recognized by plasmacytoid dendritic cells (pDCs) and by other cells.
Richard E. Randall, Randall, Richard E, Mustapha Si-Tahar, Helen K W Law, Julien Pothlichet, Plumas, Joel, Lepelley, Alice, Mammano, Fabrizio, Helen K. W. Law, Richard E Randall, Schwartz, Olivier, Albert, Matthew L, Albert, Matthew L., Louis, Stephanie, Laurence Chaperot, Chaperot, Laurence, Stéphanie Louis, Pothlichet, Julien, Olivier Schwartz, Si-Tahar, Mustapha, Sourisseau, Marion, Schilte, Clementine, Law, Helen K. W., Law, Helen K W, Marion Sourisseau, Joël Plumas, Alice Lepelley, Clémentine Schilte, Fabrizio Mammano, Matthew L Albert, Matthew L. Albert, Randall, Richard Edward   +31 more
core   +2 more sources

Role of Innate Immune Cells in Psoriasis [PDF]

International Journal of Molecular Sciences, 2020
Psoriasis is a chronic inflammatory skin condition caused by a combination of hereditary and environmental factors. Its development is closely related to the adaptive immune response. T helper 17 cells are major IL-17-producing cells, a function that plays an important role in the pathogenesis of psoriasis.
Sato, Yuki, Ogawa, Eisaku, Okuyama, Ryuhei   +2 more
openaire   +2 more sources

Modulation of the innate immune response by Yersinia enterocolitica upon systemic infection [PDF]

, 2006
Yersinia enterocolitica causes acute and chronic enteric infections and complications such as septicaemia or reactive arthritis. The survival strategy of Y.
Matteoli, Gianluca
core   +1 more source

Modulation by luminal factors on the functions and migration of intestinal innate immunity

Frontiers in Immunology, 2023
Luminal antigens, nutrients, metabolites from commensal bacteria, bile acids, or neuropeptides influence the function and trafficking of immune cells in the intestine.
Masaaki Higashiyama, Soichiro Miura, Ryota Hokari   +2 more
doaj   +1 more source

Osteoclasts—the innate immune cells of the bone

Autoimmunity, 2008
Osteopenia and periarticular bony erosion are consequences of chronic inflammatory autoimmune disease due to an imbalance of osteoclast activity relative to new bone formation. Osteoclasts, which are specialized as the only bone resorbing cell type, are differentiated from hematopoietic myeloid precursor cells. Inflammatory signals mediated by multiple
Yalei, Wu, Mary Beth, Humphrey, Mary C, Nakamura   +2 more
openaire   +2 more sources

Glycosylation of Candida albicans cell wall proteins is critical for induction of innate immune responses and apoptosis of epithelial cells. [PDF]

, 2012
C. albicans is one of the most common fungal pathogen of humans, causing local and superficial mucosal infections in immunocompromised individuals. Given that the key structure mediating host-C.
Tilo Biedermann (116048), Jeanette Wagener (116035), Weig, Michael S., Susanne Kaesler (116042), Jeanette Wagener, Bader, Oliver, Schaller, Martin, Albert D. de Boer (116041), Naglik, Julian R., Naglik, Julian R, Piet W. J. de Groot (116040), Daniela Mailänder-Sanchez (116045), Weindl, Günther, Julian R Naglik, Hans Christian Korting (116050), Günther Weindl, Martin Schaller, Julian R. Naglik (116049), Selvam Thavaraj (116043), Albert D de Boer, Oliver Bader, Hans Christian Korting, de Boer, Albert D, Albert D. De Boer, Oliver Bader (116044), Claudia Borelli (116046), Selvam Thavaraj, Borelli, Claudia, Daniela Mailänder-Sanchez, Susanne Kaesler, Günther Weindl (116038), Biedermann, Tilo, Michael Weig, Michael Weig (116047), Claudia Borelli, de Boer, Albert D., Weindl, Guenther, Mailaender-Sanchez, Daniela, Julian R. Naglik, Kaesler, Susanne, de Groot, Piet W. J., Thavaraj, Selvam, Korting, Hans Christian, Mailänder-Sanchez, Daniela, Apoptosis Of Epithelial Cells, Piet W. J. De Groot, Martin Schaller (116051), Wagener, Jeanette, Weig, Michael, Tilo Biedermann, Piet W J de Groot, Naglik, Julian R; id_orcid, de Groot, Piet W J, Bader Oliver, Biedermann Tilo, Naglik Julian R., Weig Michael, Korting Hans Christian, Schaller Martin, de Groot Piet W. J., Kaesler Susanne, Mailänder-Sanchez Daniela, Borelli Claudia, Mailänder-Sánchez, Daniela Isabel, Thavaraj Selvam, Weindl Günther, Wagener Jeanette, de Boer Albert D.   +67 more
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Innate Lymphoid Cells in Inflammation and Immunity [PDF]

Immunity, 2014
Innate lymphoid cells (ILCs) were first described as playing important roles in the development of lymphoid tissues and more recently in the initiation of inflammation at barrier surfaces in response to infection or tissue damage. It has now become apparent that ILCs play more complex roles throughout the duration of immune responses, participating in ...
Mckenzie, Andrew N.J., Spits, Hergen, Eberl, Gerard   +2 more
openaire   +2 more sources

Role of Innate lymphocytes in infection and inflammation

Frontiers in Immunology, 2012
Cooperation of innate and adaptive immune responses is critical for the protective immunity against various invading microbes. Distinct types of effector T cells play different roles in adaptive immune responses.
Shigeo eKoyasu, Kazuyo eMoro
doaj   +1 more source