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Innate Lymphoid Cells in Tumor Immunity [PDF]
Innate lymphoid cells (ILCs) are a group of immune cells of the lymphoid lineage that do not possess antigen specificity. The group includes natural killer (NK) cells, lymphoid tissue inducer (LTi) cells and the recently identified ILC1s, ILC2s and ILC3s.
Jasper Van Beek +3 more
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Be aware, innate immune cells remember [PDF]
Contains fulltext : 199946.pdf (Publisher’s version ) (Open Access)
Riksen, N.P., Netea, M.G., Netea, M.G.
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IntroductionThe mechanisms underlying innate immune memory (trained immunity) comprise epigenetic reprogramming of transcriptional pathways associated with alterations of intracellular metabolism.
Emmanuel Chaumond +8 more
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In Vivo Zymosan Treatment Induces IL15-Secreting Macrophages and KLRG1-Expressing NK Cells in Mice
Beta-glucan (β-glucan) is a natural polysaccharide produced by fungi, bacteria, and plants. Although it has been reported that β-glucan enhances innate immune memory responses, it is unclear whether different types of β-glucans display similar immune ...
Hyun Jung Park +7 more
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Immune checkpoints on innate lymphoid cells [PDF]
In this issue of JEM, Taylor et al. (https://doi.org/10.1084/jem.20161653) describe PD-1 as a critical negative regulator of group 2 innate lymphoid cells (ILC-2s). PD-1 intrinsically controls proliferation and cytokine production of both mouse and human ILC-2s.
Chiossone, Laura, Vivier, Eric
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Stretching the Function of Innate Immune Cells [PDF]
The importance of innate immune cells to sense and respond to their physical environment is becoming increasingly recognized. Innate immune cells (e.g. macrophages and neutrophils) are able to receive mechanical signals through several mechanisms.
Erica M. Orsini +8 more
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Toll-Like Receptors in Natural Killer Cells and Their Application for Immunotherapy
Innate immunity represents the first barrier for host defense against microbial infection. Toll-like receptors (TLRs) are the most well-defined PRRs with respect to PAMP recognition and induction of innate immune responses.
Ji-Yoon Noh +4 more
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Innate immunity and immunotherapy for hemorrhagic shock
Hemorrhagic shock (HS) is a shock result of hypovolemic injury, in which the innate immune response plays a central role in the pathophysiology ofthe severe complications and organ injury in surviving patients.
Qingxia Huang +9 more
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Targeting Innate Immune Cells for Immunotherapy [PDF]
Referencia
Leandro J. Carreño +4 more
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Vascular Endothelial Cells and Innate Immunity [PDF]
In addition to the roles of endothelial cells (ECs) in physiological processes, ECs actively participate in both innate and adaptive immune responses. We previously reported that, in comparison to macrophages, a prototypic innate immune cell type, ECs have many innate immune functions that macrophages carry out, including cytokine ...
Ying Shao +11 more
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