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Resident Innate Immune Cells in the Cornea [PDF]
The cornea is a special interface between the internal ocular tissue and the external environment that provides a powerful chemical, physical, and biological barrier against the invasion of harmful substances and pathogenic microbes. This protective effect is determined by the unique anatomical structure and cellular composition of the cornea ...
Jun Liu, Zhijie Li
openaire +3 more sources
Innate Immunity Cells and the Neurovascular Unit [PDF]
Recent studies have clarified many still unknown aspects related to innate immunity and the blood-brain barrier relationship. They have also confirmed the close links between effector immune system cells, such as granulocytes, macrophages, microglia, natural killer cells and mast cells, and barrier functionality.
Ivan Presta +9 more
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Targeting Innate Immune Cells for Immunotherapy [PDF]
Referencia
Leandro J. Carreño +4 more
doaj +5 more sources
Innate Immune Cells in Inflammation and Cancer [PDF]
Abstract The innate immune system has evolved in multicellular organisms to detect and respond to situations that compromise tissue homeostasis. It comprises a set of tissue-resident and circulating leukocytes primarily designed to sense pathogens and tissue damage through hardwired receptors and eliminate noxious sources by mediating ...
Roni, Nowarski +3 more
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Chitin modulates innate immune responses of keratinocytes. [PDF]
Chitin, after cellulose the second most abundant polysaccharide in nature, is an essential component of exoskeletons of crabs, shrimps and insects and protects these organisms from harsh conditions in their environment.
Korting, Hans Christian +14 more
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CD4+CD25+ TR cells suppress innate immune pathology through cytokine-dependent mechanisms [PDF]
Copyright @ 2003 The Rockefeller University PressCD4+CD25+ regulatory T (TR) cells can inhibit a variety of autoimmune and inflammatory diseases, but the precise mechanisms by which they suppress immune responses in vivo remain unresolved.
Maloy, Kevin +19 more
core +1 more source
Innate Lymphoid Cells in Tumor Immunity [PDF]
Innate lymphoid cells (ILCs) are a group of immune cells of the lymphoid lineage that do not possess antigen specificity. The group includes natural killer (NK) cells, lymphoid tissue inducer (LTi) cells and the recently identified ILC1s, ILC2s and ILC3s.
Jasper Van Beek +3 more
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Vascular Endothelial Cells and Innate Immunity [PDF]
In addition to the roles of endothelial cells (ECs) in physiological processes, ECs actively participate in both innate and adaptive immune responses. We previously reported that, in comparison to macrophages, a prototypic innate immune cell type, ECs have many innate immune functions that macrophages carry out, including cytokine ...
Ying Shao +11 more
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Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes [PDF]
Protective responses to microorganisms involve the nonspecific but rapid defence mechanisms of the innate immune system, followed by the specific but slow defence mechanisms of the adaptive immune system. Located as sentinels at the interface between the
Cols, M +5 more
core +1 more source
In Vivo Zymosan Treatment Induces IL15-Secreting Macrophages and KLRG1-Expressing NK Cells in Mice
Beta-glucan (β-glucan) is a natural polysaccharide produced by fungi, bacteria, and plants. Although it has been reported that β-glucan enhances innate immune memory responses, it is unclear whether different types of β-glucans display similar immune ...
Hyun Jung Park +7 more
doaj +1 more source

