Results 31 to 40 of about 154,668 (248)

Innate immune memory in mammals

open access: yesSeminars in Immunology, 2016
Innate and adaptive immunity have evolved as sophisticated mechanisms of host defence against invading pathogens. Classically the properties attributed to innate immunity are its rapid pleiotropic response, and to adaptive immunity its specificity and ability to retain a long-term memory of past infections.
Hamon, Melanie, Quintin, Jessica
openaire   +3 more sources

Recombinant BCG Expressing the Subunit 1 of Pertussis Toxin Induces Innate Immune Memory and Confers Protection against Non-Related Pathogens

open access: yesVaccines, 2022
BCG has shown the ability to induce protection against unrelated pathogens, which likely depends on an immune mechanism known as innate immune memory or trained immunity.
Alex I. Kanno   +3 more
doaj   +1 more source

The specifics of innate immune memory

open access: yesScience, 2020
Innate immune cells develop specific memory involved in transplant rejection in ...
Dominguez Andres, J., Netea, M.G.
openaire   +4 more sources

Personalised Profiling of Innate Immune Memory Induced by Nano-Imaging Particles in Human Monocytes

open access: yesFrontiers in Immunology, 2021
Engineered nanoparticles used for medical purposes must meet stringent safety criteria, which include immunosafety, i.e., the inability to activate possibly detrimental immune/inflammatory effects.
Giacomo Della Camera   +13 more
doaj   +1 more source

Thy1+ NK [corrected] cells from vaccinia virus-primed mice confer protection against vaccinia virus challenge in the absence of adaptive lymphocytes. [PDF]

open access: yesPLoS Pathogens, 2011
While immunological memory has long been considered the province of T- and B-lymphocytes, it has recently been reported that innate cell populations are capable of mediating memory responses. We now show that an innate memory immune response is generated
Geoffrey O Gillard   +7 more
doaj   +1 more source

Microarray expression analysis of genes involved in innate immune memory in peritoneal macrophages

open access: yesGenomics Data, 2016
Immunological memory has been believed to be a feature of the adaptive immune system for long period, but recent reports suggest that the innate immune system also exhibits memory-like reaction.
Keisuke Yoshida   +5 more
doaj   +1 more source

Immunological memory within the innate immune system [PDF]

open access: yesThe EMBO Journal, 2014
Immune memory has traditionally been the domain of the adaptive immune system, present only in antigen-specific T and B cells. The purpose of this review is to summarize the evidence for immunological memory in lower organisms (which are not thought to possess adaptive immunity) and within specific cell subsets of the innate immune system.
Sun, J. C., Ugolini, S., Vivier, E.
openaire   +2 more sources

Immune memory characteristics of innate lymphoid cells [PDF]

open access: yesCurrent Opinion in Infectious Diseases, 2019
Purpose of review Immune memory is essential for host defense against invaders and it is also used as a basis for vaccine development. For these reasons, it is crucial to understand its molecular basis. In this review, we describe recent findings on memory characteristics of innate-like lymphocytes and its contribution to host ...
Placek, K.   +3 more
openaire   +3 more sources

Differential induction of innate memory in porcine monocytes by -glucan or bacillus Calmette-Guerin

open access: yesInnate Immunity, 2021
Innate immunomodulation via induction of innate memory is one mechanism to alter the host’s innate immune response to reduce or prevent disease. Microbial products modulate innate responses with immediate and lasting effects.
Kristen A Byrne   +2 more
doaj   +1 more source

Trained Immunity: A Memory for Innate Host Defense [PDF]

open access: yesCell Host & Microbe, 2011
Immune responses in vertebrates are classically divided into innate and adaptive, with only the latter being able to build up immunological memory. However, although lacking adaptive immune responses, plants and invertebrates are protected against reinfection with pathogens, and invertebrates even display transplant rejection.
Netea, M.G.   +2 more
openaire   +3 more sources

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