Functionally redundant control of cardiac hypertrophic signaling by inositol 1,4,5-trisphosphate receptors [PDF]
Journal of Molecular and Cellular Cardiology, 2017 Anja Karlstaedt +2 more
exaly +2 more sources
Waves of calcium depletion in the sarcoplasmic reticulum of vascular smooth muscle cells: an inside view of spatiotemporal Ca2+ regulation. [PDF]
PLoS ONE, 2013 Agonist-stimulated smooth muscle Ca2+ waves regulate blood vessel tone and vasomotion. Previous studies employing cytoplasmic Ca2+ indicators revealed that these Ca2+ waves were stimulated by a combination of inositol 1,4,5-trisphosphate- and Ca2 ...
Mitra Esfandiarei +5 more
doaj +1 more source
http://ukrbiochemjournal.org/wp-content/uploads/2015/11/Kosterin_6_13.pdf [PDF]
The Ukrainian Biochemical Journal, 2013 2- and 3-dimensional confocal imaging of Fluo-4 loaded ureteric microvesells in situ allowed us to demonstrate distinct morphology, Ca2+ signalling and contractility in myocytes of arcade arterioles and pericytes of arcade venules.
T. Burdyga, L. Borysova
doaj +1 more source
Inositol 1,4,5‐trisphosphate receptors and neurodegenerative disorders [PDF]
The FEBS Journal, 2018 The inositol 1,4,5‐trisphosphate receptor (IP3R) is an intracellular ion channel that mediates the release of calcium ions from the endoplasmic reticulum. It plays a role in basic biological functions, such as cell division, differentiation, fertilization and cell death, and is involved in developmental processes including learning, memory and behavior.
Polina A, Egorova, Ilya B, Bezprozvanny
openaire +2 more sources
Functional Role of Intracellular Calcium Receptor Inositol 1,4,5-Trisphosphate Type 1 in Rat Hippocampus after Neonatal Anoxia. [PDF]
PLoS ONE, 2017 Anoxia is one of the most prevalent causes of neonatal morbidity and mortality, especially in preterm neonates, constituting an important public health problem due to permanent neurological sequelae observed in patients.
Juliane Midori Ikebara +8 more
doaj +1 more source
Decavanadate displaces inositol 1,4,5-trisphosphate (IP3) from its receptor and inhibits IP3 induced Ca2+ release in permeabilized pancreatic acinar cells [PDF]
, 1991 Inositol 1,4,5-trisphosphate (IP3) induced Ca2+ release in digitonin permeabilized rat pancreatic acinar cells is specifically inhibited by decavanadate.
M. Gratzl +9 more
core +1 more source
Lipopolysaccharide induces endoplasmic store Ca2+-dependent inflammatory responses in lung microvessels. [PDF]
PLoS ONE, 2013 The pulmonary microvasculature plays a critical role in endotoxin-induced acute lung injury. However, the relevant signaling remain unclear. Specifically the role of endothelial Ca(2+) in the induction of endotoxin-mediated responses in lung microvessels
Kathirvel Kandasamy +3 more
doaj +1 more source
Activating calcium release through inositol 1,4,5-trisphosphate receptors without inositol 1,4,5-trisphosphate [PDF]
Proceedings of the National Academy of Sciences, 2002 Cytosolic calcium (Ca2+) is a focal point of many signal transduction pathways and modulates a diverse array of cellular activities ranging from fertilization to cell death (1). Cells generate Ca2+ signals through both internal and external Ca2+ sources.
Bootman, M.D. +2 more
openaire +2 more sources
GTP and Ca2+ Modulate the Inositol 1,4,5-Trisphosphate-Dependent Ca2+ Release in Streptolysin O-Permeabilized Bovine Adrenal Chromaffin Cells [PDF]
, 1991 The inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release was studied using streptolysin O-permeabilized bovine adrenal chromaffin cells. The IP3-induced Ca2+ release was followed by Ca2+ reuptake into intracellular compartments.
Föhr, K. J. +9 more
core +1 more source
IP3 Receptor-Mediated Calcium Signaling and Its Role in Autophagy in Cancer
Frontiers in Oncology, 2017 Calcium ions (Ca2+) play a complex role in orchestrating diverse cellular processes, including cell death and survival. To trigger signaling cascades, intracellular Ca2+ is shuffled between the cytoplasm and the major Ca2+ stores, the endoplasmic ...
Elzbieta Kania +4 more
doaj +1 more source