Results 11 to 20 of about 761,638 (295)

Inositols in Insulin Signaling and Glucose Metabolism [PDF]

open access: yesInternational Journal of Endocrinology, 2018
In the past decades, both the importance of inositol for human health and the complex interaction between glucose and inositol have been the subject of increasing consideration. Glucose has been shown to interfere with cellular transmembrane transport of
Arturo Bevilacqua, Mariano Bizzarri
doaj   +2 more sources

Preliminary Investigation of Myo-Inositol Phosphates Produced by ASUIA279 Phytase on MCF-7 Cancer Cells [PDF]

open access: yesInternational Islamic University Malaysia Engineering Journal, 2011
Phytate or myo-inositol hexakisphosphates (IP6) is widely distributed in plants like rice brans. The production of myo-inositol phosphate intermediates has received much attention due to the remarkable potential health benefits offered by the compounds ...
N. Mohd. Yusoff   +7 more
doaj   +3 more sources

Co-culturing experiments reveal the uptake of myo-inositol phosphate synthase (EC 5.5.1.4) in an inositol auxotroph of Saccharomyces cerevisiae

open access: yesMicrobial Cell Factories, 2021
Background Myo-Inositol Phosphate Synthase (MIP) catalyzes the conversion of glucose 6- phosphate into inositol phosphate, an essential nutrient and cell signaling molecule.
Erika Steele   +4 more
doaj   +1 more source

Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid Signaling

open access: yesBiomolecules, 2023
Multiple inositol polyphosphate phosphatase (MINPP1) is an enigmatic enzyme that is responsible for the metabolism of inositol hexakisphosphate (InsP6) and inositol 1,3,4,5,6 pentakisphosphate (Ins(1,3,4,5,6)P5 in mammalian cells, despite being ...
Jia Yu   +6 more
doaj   +1 more source

Inositol Phosphate Metabolism

open access: yesReactome - a curated knowledgebase of biological pathways, 2012
M. Williams
semanticscholar   +2 more sources

Metabolic engineering of Pichia pastoris for myo-inositol production by dynamic regulation of central metabolism

open access: yesMicrobial Cell Factories, 2022
Background The methylotrophic budding yeast Pichia pastoris GS115 is a powerful expression system and hundreds of heterologous proteins have been successfully expressed in this strain. Recently, P.
Qiquan Zhang   +11 more
doaj   +1 more source

Inositol Pyrophosphate Pathways and Mechanisms: What Can We Learn from Plants?

open access: yesMolecules, 2020
The ability of an organism to maintain homeostasis in changing conditions is crucial for growth and survival. Eukaryotes have developed complex signaling pathways to adapt to a readily changing environment, including the inositol phosphate (InsP ...
Caitlin Cridland, Glenda Gillaspy
doaj   +1 more source

Can Inositol Pyrophosphates Inform Strategies for Developing Low Phytate Crops?

open access: yesPlants, 2020
Inositol pyrophosphates (PP-InsPs) are an emerging class of “high-energy” intracellular signaling molecules, containing one or two diphosphate groups attached to an inositol ring, that are connected with phosphate sensing, jasmonate signaling,
Catherine Freed   +2 more
doaj   +1 more source

The Role of Inositol Hexakisphosphate Kinase in the Central Nervous System

open access: yesBiomolecules, 2023
Inositol is a unique biological small molecule that can be phosphorylated or even further pyrophosphorylated on each of its six hydroxyl groups. These numerous phosphorylation states of inositol along with the kinases and phosphatases that interconvert ...
Tyler Heitmann, James C. Barrow
doaj   +1 more source

Control of XPR1-dependent cellular phosphate efflux by InsP8 is an exemplar for functionally-exclusive inositol pyrophosphate signaling

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance Biological roles of inorganic phosphate require careful regulation of its transport across cell membranes, but mechanisms are poorly understood.
Xingyao Li   +8 more
semanticscholar   +1 more source

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