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Measurement of Second Messengers in Signal Transduction: cAMP and Inositol Phosphates
Current Protocols in Neuroscience, 1998AbstractcAMP acts as an intracellular mediator of hormone action and the importance of accurate quantitative determination of cAMP levels in cells and tissues is widely recognized. The most utilized procedures for the determination of adenylate cyclase activity in membranes are described here for measuring the conversion of [alpha‐32P]ATP into [32P ...
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Light-Induced Signal Transduction Pathway Involving Inositol Phosphates
1996Signals such as light, hormones, and gravity control diverse physiological and developmental processes throughout the life cycle of plants. How a plant senses these signals and then responds in an appropriate manner has been a subject of great interest.
S K, Sopory, M R, Chandok
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Receptors and the Inositol Phosphate-Calcium Signaling System
1994Extracellular stimuli modify [Ca2+]ithrough a variety of signaling systems. The most widespread of these is a system that signals Ca2+ mobilization through the formation of Ca2+-mobilizing messengers, the inositol polyphosphates. This inositol polyphosphate—Ca2+ signaling system is associated with many growth factor, hormone, and neurotransmitter ...
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Regulation of invertebrate longevity by inositol phosphate signaling
2003Publisher Summary One basic function of phosphoinositide lipid signaling that appears to be conserved in evolutionarily diverse organisms is control of cell growth and metabolism. In flies, phosphoinositide lipid signaling directly controls cell growth.
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Inositol phosphates - whither bound? Intracellular signalling.
Current biology : CB, 1997Many proteins are being found to bind inositol phosphates with varying degrees of specificity; the variety of domains that can bind inositol phosphates suggests convergent evolution, but the functions of most of the binding sites are not yet clear.
R, Irvine, P, Cullen
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[Membrane signals: role of the inositol phosphate system].
Recenti progressi in medicina, 1990Current information on cellular communications through plasmatic or synaptic mediators raises a great deal of questions about intracellular messengers diffusion and the apparent difference between the large number of intercellular mediators, or first messengers, and the few number of intracellular mediators, or second messengers.
L, Malanca, M, Camici
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Transcriptional regulation: a new dominion for inositol phosphate signaling?
BioEssays, 2000The diverse phosphorylation patterns of the six-carbon inositol ring generates a mesmerizing wealth of inositol phosphates but we have little insight into the precise cellular roles of most members of this family. Therefore, new information on these roles is very welcome.
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ITPK1 Is an InsP6/ADP Phosphotransferase That Controls Phosphate Signaling in Arabidopsis
Molecular Plant, 2021Esther Lange +2 more
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Inositol Signaling in the Basidiomycete Fungus Schizophyllum Commune
Journal of Fungi (Basel, Switzerland), 2021Thomas Krüger +2 more
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