Results 61 to 70 of about 1,340,779 (272)

Phosphate Homeostasis − A Vital Metabolic Equilibrium Maintained Through the INPHORS Signaling Pathway

Frontiers in Microbiology, 2020
Cells face major changes in demand for and supply of inorganic phosphate (Pi). Pi is often a limiting nutrient in the environment, particularly for plants and microorganisms.
Sisley Austin, Andreas Mayer
doaj   +1 more source

inositol phosphate metabolism-html

, 2014
unigenes associated with inositol phosphate ...
Karen Fugate (480954)
core   +1 more source

Salvianolic Acid a Disrupts the HSP90α‐AKT‐PERK Ternary Complex to Alleviate Atherosclerosis by Activating Endoplasmic Reticulum Stress of Senescent Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Salvianolic acid A (SAA) selectively induces senescent vascular smooth muscle cell apoptosis, alleviating atherosclerosis. Mechanistically, SAA targets heat shock protein 90 alpha (HSP90α) to disrupt the protein inase B (AKT)‐PRKR‐Like Endoplasmic Reticulum Kinase (PERK) scaffold, driving ubiquitin‐proteasome‐dependent AKT degradation.
Xiuya Guan, Mengkai Lu, Xinhai Cui, Dawei Zhang, Lei Zhang, Lin Lin, Yuan Li, Yuanlong Hu, Chao Li   +8 more
wiley   +1 more source

inositol phosphate metabolism-png

, 2014
unigenes associated with inositol phosphate ...
Karen Fugate (480954)
core   +1 more source

Isolation of myo-inositol-1-phosphate synthetase from wild type and an inositol-less variant Neurospora crassa [PDF]

, 1977
Isolation of myo-inositol-1-phosphate synthetase from wild type and an inositol-less ...
Szabolcs, M., Kiss, A., Szabo, G., M. Schablik, Zsindely, A., M. Szabolcs, G. Szabo, A. Kiss, J. Ardi, Ardi, J., Schablik, M., A. Zsindely   +11 more
core   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Activities and Structure-Function Analysis of Fission Yeast Inositol Pyrophosphate (IPP) Kinase-Pyrophosphatase Asp1 and Its Impact on Regulation of pho1 Gene Expression

mBio, 2022
Inositol pyrophosphates (IPPs) are signaling molecules that regulate cellular phosphate homeostasis in diverse eukaryal taxa. In fission yeast, mutations that increase 1,5-IP8 derepress the PHO regulon while mutations that ablate IP8 synthesis are PHO ...
Bradley Benjamin, Angad Garg, Nikolaus Jork, Henning J. Jessen, Beate Schwer, Stewart Shuman   +5 more
doaj   +1 more source

Integrated Multi-Omics Analysis of <i>Polygonatum odoratum</i> Polysaccharide in D-Galactose-Treated Mice Reveals Changes in Oxidative Stress Markers and Gut Microbiota. [PDF]

Food Sci Nutr
This study evaluated the effects of Polygonatum odoratum polysaccharide (POP) in D‐galactose‐treated mice using hippocampal histology, oxidative stress measurements, and integrated multi‐omics analyses. Results showed improved hippocampal histology and oxidative stress markers, accompanied by changes in gut bacterial composition, serum metabolites, and
Li W, Huang Y, Zhang W, Li S, Li L.
europepmc   +2 more sources

Study of the regulation of Fab1p, a phosphatidylinositol 3-phosphate 5 kinase in Saccharomyces cerevisiae. [PDF]

, 2005
The Saccharomyces cerevisiae protein Fab1p is the archetypal type III phosphatidyl inositol phosphate kinase. This family of enzymes is universal to all eukaryotes and is responsible for the synthesis of phosphatidylinositol 3,5-bisphosphate from ...
Phelan, J.P., Phelan, John Paul
core  

ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland

Advanced Science, EarlyView.
In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu, Jiqing Wang, Zhiyun Hao, Mingna Li, Huimin Zhen, Yuan Liu, Guoyong Zhao, Chunyan Ren, Xuelan Zhou, Haixiong Hu, Mingjie Li, Nan Shi   +11 more
wiley   +1 more source