Results 41 to 50 of about 58,667 (143)
A novel method for the purification of inositol phosphates from biological samples reveals that no phytate is present in human plasma or urine [PDF]
Inositol phosphates are a large and diverse family of signalling molecules. While genetic studies have discovered important functions for them, the biochemistry behind these roles is often not fully characterized.
Miranda S. C. Wilson +4 more
doaj +1 more source
Thiamine Diphosphate‐Dependent Biocatalysis in the 21st Century
This account summarizes the major discoveries and recent advances, highlighting the biocatalytic abilities, mechanistic studies, and feature‐based classification that are shaping emerging perspectives on thiamine diphosphate (ThDP)‐dependent catalysis.
Lucrezia Lanza +2 more
wiley +1 more source
Phosphate and calcium ions are nutrients that play key roles in growth, differentiation and the production of bioactive secondary metabolites in filamentous fungi. Phosphate concentration regulates the biosynthesis of hundreds of fungal metabolites.
Juan F. Martín
doaj +1 more source
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
Inositol Pyrophosphate Pyrotechnics
Physiologic roles of highly phosphorylated inositol phosphates, including those containing pyrophosphate groups, have been the focus of much recent interest.
Snyder, Solomon H. +2 more
core +1 more source
Cellular adaptations of fission yeast to inositol starvation
Inositol is an essential nutrient and a precursor of phosphorylated metabolites that play important roles in cell physiology. Here we characterize the impact of intracellular inositol deficiency, taking advantage of fission yeast Schizosaccharomyces ...
Ana M. Sanchez +6 more
doaj +1 more source
A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors. [PDF]
Pharmacological tools-'chemical probes'-that intervene in cell signaling cascades are important for complementing genetically-based experimental approaches.
Brandi M Baughman +8 more
doaj +1 more source
We explored genomic signatures of balancing selection and selective sweep in the northern medaka, Oryzias sakaizumii in Japan by performing whole‐genome resequencing of wild individuals. In addition, we reevaluated the population genetic structure and admixture of Oryzias latipes and O.
Shingo Fujimoto +9 more
wiley +1 more source
Nitrogen Fertilization Temporarily Enhances Phosphatase Activity in a High‐P Loamy Sand
ABSTRACT Background Efficient plant utilization of soil phosphorus (P) is essential to reduce dependence on mineral P fertilizers in intensive agriculture. Input of mineral nitrogen (N) fertilizers and its chemical form may influence the activity of P mineralizing enzymes, but how this interaction operates under field conditions in a soil with high P ...
Ingeborg F. Pedersen +3 more
wiley +1 more source
Potential Phosphorus Uptake Mechanisms in the Deep Sedimentary Biosphere
Our understanding of phosphorus (P) dynamics in the deep subseafloor environment remains limited. Here we investigate potential microbial P uptake mechanisms in oligotrophic marine sediments beneath the North Atlantic Gyre and their effects on the ...
Delphine Defforey +8 more
doaj +1 more source

