Results 61 to 70 of about 12,071 (167)
Association study of crude seed protein and fat concentration in a USDA pea diversity panel
The Plant Genome, Volume 18, Issue 1, March 2025.Abstract Pea (Pisum sativum L.) is a key rotational crop and is increasingly important in the food processing sector for its protein. This study focused on identifying diverse high seed protein concentration (SPC) lines in pea plant genetic resources.
Renan Uhdre +15 more
wiley +1 more source
Inositol pyrophosphates: Why so many phosphates? [PDF]
Advances in Biological Regulation, 2015 The inositol pyrophosphates (PP-InsPs) are a specialized group of "energetic" signaling molecules found in yeasts, plants and animals. PP-InsPs boast the most crowded three dimensional phosphate arrays found in Nature; multiple phosphates and diphosphates are crammed around the six-carbon, inositol ring.
openaire +3 more sources
The OX-44 molecule couples to signaling pathways and is associated with CD2 on rat T lymphocytes and a natural killer cell line. [PDF]
, 1992 The MRC OX-44 molecule, which is expressed on all peripheral leukocytes, identifies the subset of thymocytes capable of proliferating in response to alloantigens and lectins (Paterson, D.J., J.R. Green, W.A. Jefferies, M. Puklavec, and A.F.
Bell, GM +3 more
core +2 more sources
Anti‐Prion Systems in Saccharomyces cerevisiae
Journal of Neurochemistry, Volume 169, Issue 3, March 2025.Yeast pathogenic prions have the same in‐register parallel folded β‐sheet architecture as infectious amyloids of human transmissible spongiform encephalopathy, Alzheimer's disease, Parkinson's disease, and type 2 diabetes. Six anti‐prion systems in yeast (identified by their gene names) together lower the load of prions detected ~5000‐fold by blocking ...
Reed B. Wickner +2 more
wiley +1 more source
Inositol Pyrophosphates: Energetic, Omnipresent and Versatile Signalling Molecules [PDF]
Journal of the Indian Institute of Science, 2017 Inositol pyrophosphates (PP-IPs) are a class of energy-rich signalling molecules found in all eukaryotic cells. These are derivatives of inositol that contain one or more diphosphate (or pyrophosphate) groups in addition to monophosphates. The more abundant and best studied PP-IPs are diphosphoinositol pentakisphosphate (IP7) and bis-diphosphoinositol ...
Shubhra Ganguli +6 more
openaire +3 more sources
The Significance of Mono‐ and Dual‐Effective Agents in the Development of New Antifungal Strategies
Chemical Biology &Drug Design, Volume 105, Issue 1, January 2025.The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates.
Cengiz Zobi, Oztekin Algul
wiley +1 more source
Acanthamoeba castellanii induces host cell death via a phosphatidylinositol 3-kinase-dependent mechanism [PDF]
, 2005 Granulomatous amoebic encephalitis due to Acanthamoeba castellanii is a serious human infection with fatal consequences, but it is not clear how the circulating amoebae interact with the blood-brain barrier and transmigrate into the central nervous ...
Alsam, S. +5 more
core +3 more sources
Journal of Cellular and Molecular Medicine, Volume 29, Issue 2, January 2025.ABSTRACT The hypoxic microenvironment is crucial for tumour cell growth and invasiveness. Tumour tissue results from adaptation to reduced oxygen availability. Hypoxia first activates pro‐angiogenic signals for alleviation. Pathologic, tumour angiogenesis maintains hypoxia, impairing treatment outcomes. Vessel normalisation requires physioxia.
Sabina Koj +6 more
wiley +1 more source
Physiologia Plantarum, Volume 177, Issue 1, January/February 2025.Abstract In the context of climate changing environments, microalgae can be excellent organisms to understand molecular mechanisms that activate survival strategies under stress. Chlamydomonas reinhardtii signalling mutants are extremely useful to decipher which strategies photosynthetic organisms use to cope with changeable environments.
Rodrigo Bedera‐García +3 more
wiley +1 more source
Cellular IP6 Levels Limit HIV Production while Viruses that Cannot Efficiently Package IP6 Are Attenuated for Infection and Replication [PDF]
, 2019 Summary: HIV-1 hijacks host proteins to promote infection. Here we show that HIV is also dependent upon the host metabolite inositol hexakisphosphate (IP6) for viral production and primary cell replication.
Böcking, Till +10 more
core +3 more sources