Results 61 to 70 of about 4,083 (158)

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Genetic Parameters and Genome‐Wide Association Studies for Fertility and Reproduction Traits in U.S. Katahdin Sheep Based on the Single‐Step GBLUP Methodology

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina, Ronald M. Lewis, Bradley A. Freking, Joan M. Burke, Thomas W. Murphy, Carrie S. Wilson, Luiz F. Brito   +6 more
wiley   +1 more source

INSULIN AND INSULIN RESISTANCE: NEW MOLECULE MARKERS AND TARGET MOLECULE FOR THE DIAGNOSIS AND THERAPY OF DISEASES OF THE CENTRAL NERVOUS SYSTEM

Бюллетень сибирской медицины, 2013
The review summarizes current data on the role of insulin in the regulation of t glucose metabolism in the central nervous system at physiologic and pathologic conditions.
A. B. Salmina, N. A. Yauzina, N. V. Kuvacheva, M. M. Petrova, T. Ye. Taranushenko, N. A. Malinovskaya, O. L. Lopatina, A. V. Morgun, Ye. A. Pozhilenkova, O. S. Okuneva, G. A. Morozova, S. V. Prokopenko   +11 more
doaj   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, Volume 293, Issue 13, Page 3899-3953, July 2026.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Crystal structure of insulin-regulated aminopeptidase with bound substrate analogue provides insight on antigenic epitope precursor recognition and processing

, 2015
Aminopeptidases that generate antigenic peptides influence immunodominance and adaptive cytotoxic immune responses. The mechanisms that allow these enzymes to efficiently process a vast number of different long peptide substrates are poorly understood ...
Papakyriakou, Athanasios, Stratikos, Efstratios, Harlos, Karl, Zhao, Yuguang, Georgiadis, Dimitris, Mpakali, Anastasia, Saridakis, Emmanuel, Kokkala, Paraskevi   +7 more
core   +1 more source

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

eFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie, Wei Fang, Zean Song, Zhang Yu, Ying Zhu, Shaoping Liu   +5 more
wiley   +1 more source

Structural basis for dimerization, catalytic regulation, and substrate selectivity of the chloroplast S9D CGEP protease in Arabidopsis thaliana

Protein Science, Volume 35, Issue 6, June 2026.
Abstract S9 proteases are widely distributed across the tree‐of‐life and play essential roles in protein processing. However, the structural and mechanistic basis for protease activity in the S9D subfamily, restricted to photosynthetic eukaryotes (e.g., plants), cyanobacteria, proteobacteria and flavobacteria, is unknown. Here, we report the first high‐
Jacqueline J. Ehrlich, Pratyush Routray, Louis Enns, Klaas J. van Wijk, Toshimitsu Kawate   +4 more
wiley   +1 more source

Recent Advances in Egg White Biotechnology, Microbiology, and Quality

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT International trade in egg products has increased in recent decades to meet the rising demands of a global population, the food industry, and consumers. Egg white is a rich source of proteins and peptides suitable for various food applications. Processing egg whites is important in the food industry.
Insa Mannott, Ramona Bosse, Monika Gibis
wiley   +1 more source

Bioactive Peptide‐Enriched Requeson: A Functional Dairy Product From Whey Fermentation

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
This study presents the production of functional Requeson from whey using lactic fermentation. Proteolysis induced by Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus promotes the generation of bioactive peptides. The product is evaluated for antioxidant, ACE‐inhibitory, DPP‐IV inhibitory, mineral chelating, and antimicrobial ...
Luis‐Fernando Patlan‐Velázquez, Luis‐Guillermo González‐Olivares, Mariano García‐Garibay, Sergio Alatorre‐Santamaría, Lorena Gómez‐Ruiz, Gabriela Rodríguez‐Serrano, Ulises Carrasco‐Navarro, Alma Cruz‐Guerrero   +7 more
wiley   +1 more source

Angiotensin IV displays only low affinity for native insulin-regulated aminopeptidase (IRAP).

, 2012
<p>Radioligand binding studies revealed that Ang IV binds to insulin-regulated aminopeptidase (IRAP)/&#39;AT(4) receptors&#39; with high affinity.
E. Szemenyei, D. Tourwé, G. Vauquelin, J.P. De Backer, A. Lukaszuk, G. Tóth, H. Demaegdt   +6 more
core   +1 more source