Results 71 to 80 of about 11,143 (161)
PLoS Pathogens, 2020 Type III interferons (IFN-lambdas(λ)) are important cytokines that inhibit viruses and modulate immune responses by acting through a unique IFN-λR1/IL-10RB heterodimeric receptor.
Deanna M Santer +11 more
doaj +1 more source
Interferon lambda 4 impacts the genetic diversity of hepatitis C virus
eLife, 2019 Hepatitis C virus (HCV) is a highly variable pathogen that frequently establishes chronic infection. This genetic variability is affected by the adaptive immune response but the contribution of other host factors is unclear.
M Azim Ansari +25 more
doaj +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.Single‐cell RNA‐seq of normal and endometritis endometrium shows reduced epithelial cells and fate divergence toward ferroptosis or ribosome/antigen‐presentation programs. COL1A1+ epithelial cells act as an AP‐1–driven hub that enhances VEGFA–VEGFR signaling and remodels the vascular microenvironment.
Chengzi Tian, Zaiyi Li
wiley +1 more source
SmartBot, EarlyView.This article reviews the application of fiber Bragg grating (FBG) technology for precise force sensing in minimally invasive surgery. It outlines the fundamental working principles and algorithms used to interpret sensor data. The text surveys clinical applications across various medical fields, such as ophthalmology and vascular intervention (Table of
Shiyuan Dong +9 more
wiley +1 more source
Credit‐Driven Adaptive Grouping for Refined Cooperative Multi‐Agent Reinforcement Learning
CAAI Transactions on Intelligence Technology, EarlyView.ABSTRACT Policy heterogeneity is crucial for achieving sophisticated coordination in complex collaborative tasks, which has emerged as one of the key challenges in multi‐agent reinforcement learning (MARL) in recent years. Notably, the grouping paradigm has made remarkable progress in addressing policy heterogeneity.
Yirui Liu +6 more
wiley +1 more source
Interferon lambda: opportunities, risks and uncertainties in the fight against HCV
Frontiers in Immunology, 2014 Innate immunity is key to the fight against the daily onslaught from viruses that our bodies are subjected to. Essential to this response are the interferons (IFNs) that prime our cells to block viral pathogens. Recent evidence suggests that the Type III
Stephen M Laidlaw, Lynn B Dustin
doaj +1 more source
TriCrackNet: Trilateral Segmentation Network for Real‐Time Crack Segmentation
CAAI Transactions on Intelligence Technology, EarlyView.ABSTRACT To achieve high‐precision real‐time crack segmentation, we propose TriCrackNet, an efficient network based on a tri‐branch collaborative architecture incorporating boundary constraints, semantic parsing, and spatial refinement. In the semantic branch, efficient atrous spatial pyramid pooling (EASPP) is integrated.
Haixin Jia +5 more
wiley +1 more source
Interferon lambda protects the female reproductive tract against Zika virus infection
Nature Communications, 2019 Zika virus infections can cause devastating congenital birth defects but the underlying interactions with the host immune system are not well understood.
Elizabeth A. Caine +7 more
doaj +1 more source
Bovine Interferon Lambda Is a Potent Antiviral Against SARS-CoV-2 Infection in vitro
Frontiers in Veterinary Science, 2020 Interferon lambda (IFN-λ) is an antiviral naturally produced in response to viral infections, with activity on cells of epithelial origin and located in the mucosal surfaces.
Nancy Patricia Cardoso +8 more
doaj +1 more source
British Journal of Haematology, EarlyView.Summary Follicular lymphoma (FL) first‐line chemoimmunotherapy yields high efficacy but serious toxicity in 65% of patients. In high tumour burden treatment‐naïve FL, we aimed to exploit known immunostimulatory and cytotoxic properties of combination checkpoint inhibition (atezolizumab) and obinutuzumab (6 cycles) with positron emission tomography (PET)
Arina Martynchyk +15 more
wiley +1 more source