Interleukin-31 and Pruritic Skin. [PDF]
J Clin Med, 2021 Skin inflammation often evokes pruritus, which is the major subjective symptom in many inflammatory skin diseases such as atopic dermatitis and prurigo nodularis. Pruritus or itch is a specific sensation found only in the skin.
Furue M, Furue M.
europepmc +5 more sources
Interleukin-31 in serum and cerebrospinal fluid of dogs with syringomyelia [PDF]
BMC Veterinary Research, 2023 Background Syringomyelia is a spinal cord cavity containing cerebrospinal fluid (CSF)-like fluid. If syringomyelia asymmetrically involves the dorsal horn grey matter of the spinal cord, affected dogs show increased signs of dysesthesia and neuropathic ...
Laura Lemke +6 more
doaj +4 more sources
Interleukin-31: The Inflammatory Cytokine Connecting Pruritus and Cancer
Frontiers in Bioscience-LandmarkInterleukin 31 (IL-31) is a proinflammatory cytokine, mainly secreted by Type II helper T cells. It signals through a heterodimeric receptor complex composed of IL-31 receptor α and oncostatin-M receptor β chain.
Sabah Akhtar +8 more
doaj +4 more sources
Interleukin 31 mediates pruritus in horses. [PDF]
American Journal of Veterinary ResearchOBJECTIVE This study investigated the effects of recombinant equine IL-31 (eIL-31) in vivo and in vitro. METHODS Equine IL-31 mRNA sequences were verified by sequencing.
N. Craig +6 more
semanticscholar +6 more sources
Capsaicin suppresses interleukin-31-induced itching partially involved in inhibiting the expression of dorsal root ganglion interleukin-31 receptor A in male mice [PDF]
Neurobiology of Pain, 2022 To elucidate the mechanisms underlying the antipruritic effect of capsaicin, we investigated how topical application of capsaicin (0.01, 0.1 and 1.0% w/v) affects spontaneous scratching in NC/Nga mice, inerleukin-31 (IL-31) induced in BALB/c mice, and IL-
Iwao Arai +4 more
doaj +4 more sources
Transmembrane protein TMEM184B is necessary for interleukin-31-induced itch. [PDF]
Pain, 2022 Nociceptive and pruriceptive neurons in the dorsal root ganglia (DRG) convey sensations of pain and itch to the spinal cord, respectively. One subtype of mature DRG neurons, comprising 6% to 8% of neurons in the ganglia, is responsible for sensing ...
Larsen EG +14 more
europepmc +4 more sources
Itch in dermatomyositis: the role of increased skin interleukin-31. [PDF]
Br J Dermatol, 2018 Interleukin (IL)‐31 is implicated in pruritus associated with pruritic skin diseases like atopic dermatitis. Although pruritus is a prominent feature in dermatomyositis (DM), few studies have evaluated the pathogenesis of DM‐associated itch.
Kim HJ +6 more
europepmc +5 more sources
Increased levels of interleukin 31 (IL-31) in osteoporosis. [PDF]
BMC Immunol, 2015 Background: Several inflammatory cytokines play a key part in the induction of osteoporosis. Until now, involvement of the Th2 cytokine interleukin-31 (IL-31) in osteoporosis hadn’t yet been studied.
Ginaldi L +6 more
europepmc +8 more sources
Profile of Serum Interleukin-31 Levels in Atopic Dermatitis [PDF]
Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2017 Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by pruritic skin lesion. Pathogenesis of AD is not fully understood, but recent studies demonstrate the role of interleukin-31 (IL-31).
Dewi Kusumawati +2 more
doaj +5 more sources
Possible Association of Interleukin-31/-31RA Signalling and Basophils with Itch in Porokeratosis [PDF]
Acta Dermato-Venereologica, 2023 is missing (Short communication)
Satoshi Okuno +3 more
doaj +2 more sources