Eosinophils are a Major Source of Interleukin-31 in Bullous Pemphigoid
Acta Dermato-Venereologica, 2018 Bullous pemphigoid (BP) is characterized by substantial skin and blood eosinophilia as well as intensive pruritus. Since the pruritogenic cytokine interleukin (IL)-31 is increased in inflammatory skin diseases the aim of this study was to determine ...
Urda Rüdrich +9 more
doaj +6 more sources
Significance of interleukin-31 (IL-31) gene polymorphisms and IL-31 serum level in psoriasis in correlation with pruritus. [PDF]
Postepy Dermatol Alergol, 2021 Introduction Interleukin-31 (IL-31) impact on the development and clinical presentation of psoriasis as well as pruritus has not been widely investigated so far.
Purzycka-Bohdan D +7 more
europepmc +2 more sources
Increased serum interleukin-31 levels correlate with pruritus in psoriatic patients: a cross-sectional study in Vietnam [PDF]
Dermatology ReportsPsoriasis is recognized not only as a skin disease but also as a systemic disorder. Interleukin-31 (IL-31) may be associated with psoriasis and systemic inflammation.
Chuyen Thi Hong Nguyen +1 more
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Interleukin 31 receptor α promotes smooth muscle cell contraction and airway hyperresponsiveness in asthma [PDF]
Nature Communications, 2023 Asthma is a chronic inflammatory airway disease characterized by airway hyperresponsiveness (AHR), inflammation, and goblet cell hyperplasia. Multiple cytokines, including IFNγ, IL-4, and IL-13 are associated with asthma; however, the mechanisms ...
Santhoshi V. Akkenepally +6 more
doaj +2 more sources
Interleukin‐31: The “itchy” cytokine in inflammation and therapy [PDF]
Allergy, 2020 The cytokine interleukin‐31 has been implicated in the pathophysiology of multiple atopic disorders such as atopic dermatitis (AD), allergic rhinitis, and airway hyper‐reactivity.
A. Datsi +4 more
semanticscholar +4 more sources
The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching. [PDF]
Immunity, 2020 Summary Cutaneous wound healing is associated with the unpleasant sensation of itching. Here we investigated the mechanisms underlying this type of itch, focusing on the contribution of soluble factors released during healing.
Xu J +15 more
europepmc +2 more sources
Interleukin-31 new biomarker of infectious skin diseases
Journal of V. N. Karazin Kharkiv National University: Series Medicine, 2021 Introduction. The introduction of antiretroviral therapy has significantly improved the long-term prognosis of AIDS patients, but opportunistic infections can still be life-threatening for this population.
Diana Dorosh
doaj +3 more sources
Interleukin-31 is overexpressed in skin and serum in cutaneous T-cell lymphomas but does not correlate to pruritus. [PDF]
Postepy Dermatol Alergol, 2022 Introduction Cutaneous T-cell lymphomas (CTCL) are malignant lymphoproliferative disorders accompanied by persistent pruritus. Pruritogenic role of interleukin-31 (IL-31) has been studied extensively and was proven in atopic dermatitis (AD), while its ...
Olszewska B +11 more
europepmc +2 more sources
Interleukin-31: A Pro-inflammatory Oriented Cytokine
Frontiers in Bioscience-LandmarkType 2 immunity is represented by T helper 2 (Th2) lymphocytes and the cytokines produced downstream (Interleukin (IL)-4, IL-13, IL-31). They are increasingly recognized as pivotal mediators in the pathogenesis of immune-mediated dermatological ...
Giuseppe Murdaca +3 more
doaj +2 more sources
The ambiguous pruritogenic role of interleukin-31 in cutaneous T-cell lymphomas in comparison to atopic dermatitis: a review. [PDF]
Postepy Dermatol Alergol, 2020 Cutaneous T-cell lymphomas (CTCLs) comprise a group of chronic heterogeneous diseases of unknown pathogenesis, characterized by non-specific skin lesions such as patches, plaques and tumours.
Olszewska B +3 more
europepmc +2 more sources