Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease [PDF]
, 2007 Background/aim: Interleukin 31 (IL31), primarily expressed in activated lymphocytes, signals through a heterodimeric receptor complex consisting of the IL31 receptor alpha (IL31R\textgreeka) and the oncostatin M receptor (OSMR). The aim of this study was
Auernhammer, Christoph J. +6 more
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Definition and Characterization of an Inhibitor for Interleukin-31 [PDF]
Journal of Biological Chemistry, 2010 Interleukin-31 (IL-31) is a recently described T cell-derived cytokine, mainly produced by T helper type 2 cells and related to the IL-6 cytokine family according to its structure and receptor. IL-31 is the ligand for a heterodimeric receptor composed of a gp130-like receptor (GPL) associated with the oncostatin M receptor (OSMR).
Venereau, Emilie +11 more
openaire +3 more sources
Differential expression of skeletal muscle genes following administration of clenbuterol to exercised horses. [PDF]
, 2016 BackgroundClenbuterol, a beta2-adrenergic receptor agonist, is used therapeutically to treat respiratory conditions in the horse. However, by virtue of its mechanism of action it has been suggested that clenbuterol may also have repartitioning affects in
Chouicha, Nadira +4 more
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Изменение клеточного и гуморального иммунитета у пациентов с холодовой и хронической спонтанной крапивницей [PDF]
, 2014 холодовая крапивницаКРАПИВНИЦАИММУНИТЕТ ГУМОРАЛЬНЫЙАНТИТЕЛ ОБРАЗОВАНИЕИММУНИТЕТ КЛЕТОЧНЫЙхроническая спонтанная ...
Янченко, В. В. +1 more
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Frontiers in Immunology, 2021 Atopic dermatitis (AD) is a multifaceted, chronic relapsing inflammatory skin disease that affects people of all ages. It is characterized by chronic eczema, constant pruritus, and severe discomfort. AD often progresses from mild annoyance to intractable
Jianghui Meng +12 more
doaj +1 more source
The role of the novel Th17 cytokine IL-26 in intestinal inflammation [PDF]
, 2008 Background and aims: Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in human disease is completely unknown. The aim of this study was to analyse its
Auernhammer, Christoph J. +7 more
core +1 more source
A genome-wide association study for somatic cell score using the Illumina high-density bovine beadchip identifies several novel QTL potentially related to mastitis susceptibility [PDF]
, 2013 peer-reviewedMastitis is an inflammation-driven disease of the bovine mammary gland that occurs in response to physical damage or infection and is one of the most costly production-related diseases in the dairy industry worldwide.
Alan eFahey +7 more
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Role of genetic aspect in pathogenesis of atopic dermatitis [PDF]
, 2013 The pathogenesis of atopic dermatitis (AD) is a very complicated process that involves an intricate array of molecules. Nowadays it is generally accepted that cytokines play an important role in the progression of the clinical presentation of atopic ...
Wesserling Martyna
core +1 more source
Association of mastocytosis with interleukin 31 gene polymorphism [PDF]
Clin Transl Allergy, 2015 Mastocytosis is a rare disease characterized by activating KIT mutations and clonal expansion of mast cells (MCs) in tissues, particularly in skin and bone marrow. Symptoms of mastocytosis always correlate with the extent of MC infiltration and include urticaria pigmentosa, anaphylaxis, flushing, headache, diarrhea, osteoporosis and pruritus ...
Nedoszytko B +3 more
europepmc +3 more sources
Neurochemical characterization of pERK-expressing spinal neurons in histamine-induced itch [PDF]
, 2015 Date of Acceptance: 08/07/2015 Acknowledgements This work was supported by grants from the Ministry of Science and Technology of China (2012CB966904, 2011CB51005), National Natural Science Foundation of China (31271182, 81200692, 91232724, 81200933 ...
Chai, Guo-Dong +11 more
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