Results 91 to 100 of about 176,830 (333)
A Dopamine-Acetylcholine Cascade: Simulating Learned and Lesion-Induced Behavior of Striatal Cholinergic Interneurons [PDF]
, 2007 The "teaching signal" that modulates reinforcement learning at cortico-striatal synapses may be a sequence composed of an adaptively scaled DA burst, a brief ACh burst, and a scaled ACh pause.
Bullock, Daniel, Tan, Can Ozan
core +1 more source
The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
Advanced Science, EarlyView.The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
A Sweet Talk: The Molecular Systems of Perineuronal Nets in Controlling Neuronal Communication
Frontiers in Integrative Neuroscience, 2017 Perineuronal nets (PNNs) are mesh-like structures, composed of a hierarchical assembly of extracellular matrix molecules in the central nervous system (CNS), ensheathing neurons and regulating plasticity.
Heleen M. van 't Spijker +2 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2023 In addition to neuronal migration, brain development, and adult plasticity, the extracellular matrix protein Reelin has been extensively implicated in human psychiatric disorders such as schizophrenia, bipolar disorder, and autism spectrum disorder ...
Mònica Pardo +28 more
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Morphological diversity and connectivity of hippocampal interneurons
Cell and Tissue Research, 2018 The mammalian forebrain is constructed from ensembles of neurons that form local microcircuits giving rise to the exquisite cognitive tasks the mammalian brain can perform.
Sam A. Booker, Imre Vida
semanticscholar +1 more source
Advanced Science, EarlyView.Utilizing dual‐site fiber photometry, this study examines cortico‐striatal coupling with cell type resolution, identifying behavior‐ and cell type‐specific cortico striatal decoupling and its dopamine‐dependent mechanism in a Parkinson's disease mouse model.
Xu‐Ran Yao +4 more
wiley +1 more source
eLife, 2019 GABAergic fast-spiking parvalbumin-positive (PV) interneurons are frequently myelinated in the cerebral cortex. However, the factors governing the topography of cortical interneuron myelination remain incompletely understood.
Jeffrey Stedehouder +10 more
doaj +1 more source
Nature Communications, 2017 Activity in hippocampal area CA1 is essential for consolidating episodic memories, but it is unclear how CA1 activity patterns drive memory formation.
Nicolette Ognjanovski +6 more
semanticscholar +1 more source
Guided Graph Spectral Embedding: Application to the C. elegans Connectome
, 2019 Graph spectral analysis can yield meaningful embeddings of graphs by providing insight into distributed features not directly accessible in nodal domain.
Bolton, Thomas A. W. +4 more
core +2 more sources
The Auditory System of the Dipteran Parasitoid Emblemasoma auditrix (Sarcophagidae) [PDF]
, 2016 Several taxa of insects evolved a tympanate ear at different body positions, whereby the ear is composed of common parts: a scolopidial sense organ, a tracheal air space, and a tympanal membrane. Here, we analyzed the anatomy and physiology of the ear at
Kampschulte, Marian +5 more
core +1 more source