Results 121 to 130 of about 176,830 (333)

The cellular and synaptic architecture of the mechanosensory dorsal horn [PDF]

open access: yes, 2017
The deep dorsal horn is a poorly characterized spinal cord region implicated in processing low-threshold mechanoreceptor (LTMR) information. We report an array of mouse genetic tools for defining neuronal components and functions of the dorsal horn LTMR ...
Abraira   +80 more
core   +1 more source

SAGE: Spatially Aware Gene Selection and Dual‐View Embedding Fusion for Domain Identification in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He   +5 more
wiley   +1 more source

VIP Modulation of Hippocampal Synaptic Plasticity: A Role for VIP Receptors as Therapeutic Targets in Cognitive Decline and Mesial Temporal Lobe Epilepsy

open access: yesFrontiers in Cellular Neuroscience, 2020
Vasoactive intestinal peptide (VIP) is an important modulatory peptide throughout the CNS acting as a neurotransmitter, neurotrophic or neuroprotective factor.
Diana Cunha-Reis   +3 more
doaj   +1 more source

Key Aspects of Neurovascular Control Mediated by Specific Populations of Inhibitory Cortical Interneurons

open access: yesbioRxiv, 2019
Inhibitory interneurons can evoke vasodilation and vasoconstriction, making them potential cellular drivers of neurovascular coupling. However, the specific regulatory roles played by particular interneuron subpopulations remain unclear.
L. Lee   +9 more
semanticscholar   +1 more source

Subventricular zone stem cells are heterogeneous with respect to their embryonic origins and neurogenic fates in the adult olfactory bulb [PDF]

open access: yes, 2007
Wedetermined the embryonic origins of adult forebrain subventricular zone (SVZ) stem cells by Cre-lox fate mapping in transgenic mice. We found that all parts of the telencephalic neuroepithelium, including the medial ganglionic eminence and lateral ...
C.H. Papadimitriou   +8 more
core   +3 more sources

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

open access: yesAdvanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin   +15 more
wiley   +1 more source

Distinct roles of parvalbumin and somatostatin interneurons in gating the synchronization of spike times in the neocortex

open access: yesScience Advances, 2019
Sensory information–driven spikes are synchronized across cortical layers by distinct subtypes of interneurons. Synchronization of precise spike times across multiple neurons carries information about sensory stimuli.
H. Jang   +5 more
semanticscholar   +1 more source

Summation of visual and mechanosensory feedback in Drosophila flight control [PDF]

open access: yes, 2004
The fruit fly Drosophila melanogaster relies on feedback from multiple sensory modalities to control flight maneuvers. Two sensory organs, the compound eyes and mechanosensory hindwings called halteres, are capable of encoding angular velocity of the ...
Dickinson, Michael H., Sherman, Alana
core   +1 more source

Spikoder: Dual‐Mode Graphene Neuron Circuit for Hardware Intelligence

open access: yesAdvanced Intelligent Systems, EarlyView.
Spikoder, a graphene leaky integrate‐and‐fire circuit that operates as an encoder and a neuron in a spiking neural network (SNN), is introduced. A Spikoder‐driven double‐layer SNN shows an accuracy of 97.37% for the classification of the Modified National Institute of Standards and Technology dataset, demonstrating its potential as a key building block
Kannan Udaya Mohanan   +4 more
wiley   +1 more source

Parvalbumin+ interneurons obey unique connectivity rules and establish a powerful lateral-inhibition microcircuit in dentate gyrus

open access: yesNature Communications, 2018
Parvalbumin-positive (PV+) GABAergic interneurons in hippocampal microcircuits are thought to play a key role in several higher network functions, such as feedforward and feedback inhibition, network oscillations, and pattern separation.
C. Espinoza   +3 more
semanticscholar   +1 more source

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