Results 11 to 20 of about 145,959 (288)
Cells, 2021 Temporal lobe epilepsy (TLE) is characterized by changes in interneuron numbers in the hippocampus. Deep brain stimulation (DBS) is an emerging tool to treat TLE seizures, although its mechanisms are not fully deciphered. We aimed to depict the effect of
István Mihály +6 more
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Frontiers in Neuroanatomy, 2021 Early life stress has profound effects on the development of the central nervous system. We exposed 9-day-old rat pups to a 24 h maternal deprivation (MD) and sacrificed them as young adults (60-day-old), with the aim to study the effects of early stress
Milan Aksic +10 more
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eLife, 2020 Inhibitory autapses are self-innervating synaptic connections in GABAergic interneurons in the brain. Autapses in neocortical layers have not been systematically investigated, and their function in different mammalian species and specific interneuron ...
Viktor Szegedi +6 more
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Cell-to-Cell Interactions Mediating Functional Recovery after Stroke
Cells, 2021 Ischemic damage in brain tissue triggers a cascade of molecular and structural plastic changes, thus influencing a wide range of cell-to-cell interactions.
Claudia Alia +6 more
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Roles and Transcriptional Responses of Inhibitory Neurons in Learning and Memory
Frontiers in Molecular Neuroscience, 2021 Increasing evidence supports a model whereby memories are encoded by sparse ensembles of neurons called engrams, activated during memory encoding and reactivated upon recall.
Corinna Giorgi +2 more
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Building thalamic neuronal networks during mouse development
Frontiers in Neural Circuits, 2023 The thalamic nuclear complex contains excitatory projection neurons and inhibitory local neurons, the two cell types driving the main circuits in sensory nuclei.
Irene Huerga-Gómez +2 more
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Progression of Fetal Brain Lesions in Tuberous Sclerosis Complex
Frontiers in Neuroscience, 2020 Tuberous sclerosis (TSC) is a multisystem autosomal dominant genetic disorder due to loss of function of TSC1/TSC2 resulting in increased mTOR (mammalian target of rapamycin) signaling.
Antoinette Bernabe Gelot +2 more
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eLife, 2023 The way neurons in the brain rewire in larvae as they turn to adult fruit flies sheds light on how complete metamorphosis was ‘invented’ over the course of evolution.
Andreas S Thum, Bertram Gerber
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KCNQ2 channels regulate the population activity of neonatal GABAergic neurons ex vivo
Frontiers in Neurology, 2023 Over the last decade KCNQ2 channels have arisen as fundamental and indispensable regulators of neonatal brain excitability, with KCNQ2 loss-of-function pathogenic variants being increasingly identified in patients with developmental and epileptic ...
Bowen Hou +3 more
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Medial Ganglionic Eminence Progenitors Transplanted into Hippocampus Integrate in a Functional and Subtype-Appropriate Manner. [PDF]
, 2017 Medial ganglionic eminence (MGE) transplantation rescues disease phenotypes in various preclinical models with interneuron deficiency or dysfunction, including epilepsy.
Baraban, Scott C, Hsieh, Jui-Yi
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