Results 241 to 250 of about 176,830 (333)

Cytoarchitecture and myeloarchitecture of the sheep auditory cortex

Journal of Anatomy, EarlyView.
This article describes the cyto‐ and myeloarchitecture of the sheep auditory cortex. It outlines a six‐layered cortical organization, with variations in cellular types and densities. The potential location of the primary auditory cortex is indicated by parvalbumin immunostaining.
Camille Pluchot, Mélody Morisse, Maryse Meurisse, Jean‐Marie Graïc, Elodie Chaillou, Scott A. Love   +5 more
wiley   +1 more source

Autophagy regulates PVALB (parvalbumin) interneuron excitability and memory. [PDF]

Autophagy
Chalatsi T, Wosnitzka E, Kolaxi A, Fernandez LMJ, Scholler J, Batti L, Restivo L, Knott G, Lüthi A, Mameli M, Nikoletopoulou V.   +10 more
europepmc   +1 more source

Orchestrated molecular changes of proliferative, migratory‐fibrillar, synaptic, and postmigratory compartments align with precocious cortex‐type specification in the early human pallium

Journal of Anatomy, EarlyView.
Early human cortical development is organized by transient cellular compartments that define cortical types before mature layers form. Analysis of the human fetal pallium (7.5–15 PCW) shows distinct spatiotemporal trajectories for the archicortex, mesocortex, and neocortex, with delayed but accelerated differentiation in allocortical regions.
Janja Kopić, Fran Božić, Alisa Junaković Munjas, Željka Krsnik, Ivica Kostović   +4 more
wiley   +1 more source

A Meta‐Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

Journal of Sleep Research, EarlyView.
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads, Megan H. Hagenauer, Jinglin Xiong, Erin Hernandez, Duy Manh Nguyen, Annaka Saffron, Elizabeth Flandreau, Stanley Watson Jr., Huda Akil   +8 more
wiley   +1 more source

Intrinsic Cell-Class-Specific Modulation of Intracellular Chloride Levels and Inhibitory Function, in Cortical Networks, between Day and Night. [PDF]

eNeuro
Alberio L, Marshall A, Graham RT, Scott CM, Saieva L, Gartside SE, Ratto GM, Trevelyan AJ.   +7 more
europepmc   +1 more source

Spinal circuit mechanisms constrain therapeutic windows for ALS intervention: A computational modeling study.

Neurobiol Dis
Strohmer B, Grosh K, Montañana-Rosell R, Mora S, Ausborn J, Allodi I.   +5 more
europepmc   +1 more source

Parvalbumin interneurons mediate sex differences in prefrontal cortex function. [PDF]

Neuropsychopharmacology
Seney ML, Joffe ME.
europepmc   +1 more source

How copy number variations shape brain developmental disorders: Unraveling the synaptic puzzle

Psychiatry and Clinical Neurosciences, EarlyView.
Neurodevelopmental disorders (NDDs), such as schizophrenia (SCZ), Attention‐deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), learning disabilities, and intellectual disabilities (ID), are highly prevalent. One significant genetic factor associated with NDDs is copy number variations (CNVs), which are structural changes in the ...
Tianqi Wang, Kubra Trabzonlu, Emily Fullard Jones, Yasir Ahmed Syed   +3 more
wiley   +1 more source

TNEA Regulates Hippocampal Oscillation by Improving Inhibitory Synaptic Plasticity to Ameliorates Cognitive Impairment in Alzheimer's Disease. [PDF]

Adv Sci (Weinh)
Guo Z, Ni H, Lu Y, Cui Z, Wang Y, Zhu Z, Wei X, Xia C, Xu M, Du L, Yang Y, Shu S, Wang K, Wang Z, Shan C, Wang D.   +15 more
europepmc   +1 more source

The development of positron emission tomography (PET) tracer for glutamate AMPA receptors and its application to human biology and clinics

Psychiatry and Clinical Neurosciences, EarlyView.
Psychiatric and neurological disorders severely compromised patients' quality of life. Despite their urgent needs, the development of diagnostics and therapeutics based on the biological basis has made only little progress. This is due to limited evidence on the biological basis of these disorders in humans. Synapses are fundamental structural units of
Mai Hatano, Hiroki Abe, Takuya Takahashi
wiley   +1 more source