Results 21 to 30 of about 22,711 (279)
Intranasal drug delivery of olanzapine-loaded chitosan nanoparticles. [PDF]
AAPS PharmSciTech, 2014 The aim of this study was to investigate olanzapine (OZ) systemic absolute bioavailability after intranasal (i.n.) administration in vivo to conscious rabbits. Furthermore, the study investigated the potential use of chitosan nanoparticles as a delivery system to enhance the systemic bioavailability of olanzapine following intranasal administration ...
Baltzley S +3 more
europepmc +4 more sources
International Journal of Nanomedicine, 2011 Sharareh Eskandari1, Jaleh Varshosaz1, Mohsen Minaiyan2, Majid Tabbakhian11Department of Pharmaceutics, 2Department of Pharmacology, School of Pharmacy and Isfahan Pharmaceutical Sciences Research Center, Isfahan University of Medical Sciences, Isfahan ...
Sharareh Eskandari +3 more
doaj +3 more sources
Recent trends in drug delivery systems: intranasal drug delivery.
Indian journal of experimental biology, 1999 Nasal route of drug delivery is commonly known for treatment of local ailments like-cold, cough, rhinitis etc. Recently, efforts have been made to deliver various drugs, specially peptides and proteins, through nasal route for systemic use; utilizing the principles and concepts of rate controlled drug delivery and various polymers and absorption ...
V, Agarwal, B, Mishra
openaire +2 more sources
Recent developments in intranasal drug delivery of nanomedicines for the treatment of neuropsychiatric disorders [PDF]
Frontiers in MedicineRishi Paliwal +2 more
exaly +2 more sources
A promising drug delivery: Intranasal drug delivery system
International Journal of Pharmaceutical Sciences Review and Research, 2021 Pneumonic medication conveyance has acquired gigantic logical interest as of late and has advanced inside the setting of treatment for lung infections. Lung is an appealing climate for bio particles, which are exceptionally presented to enzymatic debasement in the gastrointestinal parcel just as hepatic corruption.
M. Srinivas, Y. Kalyani, J. V. C. Sharma
openaire +2 more sources
Frontiers in Pharmacology, 2022 Treatment of central nervous system (CNS) disorders is challenging using conventional delivery strategies and routes of administration because of the presence of the blood–brain barrier (BBB). This BBB restricts the permeation of most of the therapeutics
Manisha Pandey +4 more
doaj +1 more source
Brain-Targeted Intranasal Delivery of Zotepine Microemulsion: Pharmacokinetics and Pharmacodynamics [PDF]
, 2022 The purpose of our study was to improve the solubility, bioavailability, and efficacy of zotepine (ZTP) by brain-targeted intranasal delivery of microemulsion (ME) and its physicochemical properties, the pharmacokinetic and pharmacodynamic parameters ...
Maddukuri, Sravya +12 more
core +1 more source
Formulation strategies for nose-to-brain drug delivery in Alzheimer's disease
Health Sciences Review, 2023 Alzheimer's disease (AD) is a neurodegenerative brain disorder that affects memory, thinking, concentration, and judgment, ultimately hindering a person's ability to perform routine daily activities.
Manisha Vohra +3 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Intranasal administration is a drug delivery approach to provide a non-invasive pharmacological response in the central nervous system with relatively small peripheral side effects. To improve the residence time of intranasal drug delivery systems in the
Tahereh Jamshidnejad-Tosaramandani +6 more
doaj +1 more source
Intranasal Delivery of Nanoformulations: A Potential Way of Treatment for Neurological Disorders
Molecules, 2020 Although the global prevalence of neurological disorders such as Parkinson’s disease, Alzheimer’s disease, glioblastoma, epilepsy, and multiple sclerosis is steadily increasing, effective delivery of drug molecules in therapeutic quantities to the ...
Salman Ul Islam +3 more
doaj +1 more source