Results 1 to 10 of about 904,732 (368)
Biophysical Chemistry, 2010 The interpretation electrical phenomena in biomembranes is usually based on the assumption that the experimentally found discrete ion conduction events are due to a particular class of proteins called ion channels while the lipid membrane is considered ...
Heimburg, Thomas
core +5 more sources
Effect of channel block on the spiking activity of excitable membranes in a stochastic Hodgkin-Huxley model [PDF]
PHYSICAL BIOLOGY 1, pp. 61-66 (2004), 2006 The influence of intrinsic channel noise on the spontaneous spiking activity of poisoned excitable membrane patches is studied by use of a stochastic generalization of the Hodgkin-Huxley model. Internal noise stemming from the stochastic dynamics of individual ion channels is known to affect the collective properties of the whole ion channel cluster ...
Chow C C +17 more
arxiv +5 more sources
Ion exchange phase transitions in "doped" water--filled channels [PDF]
Phys. Rev. E 73, 051205 (2006), 2005 Ion transport through narrow water--filled channels is impeded by a high electrostatic barrier. The latter originates from the large ratio of the dielectric constants of the water and a surrounding media. We show that ``doping'', i.e. immobile charges attached to the walls of the channel, substantially reduces the barrier. This explains why most of the
A. Kamenev +8 more
arxiv +3 more sources
Tuning ion coordination preferences to enable selective permeation [PDF]
, 2006 Potassium (K-) channels catalyze K+ ion permeation across cellular membranes while simultaneously discriminating their permeation over Na+ ions by more than a factor of a thousand. Structural studies show bare K+ ions occupying the narrowest channel regions in a state of high coordination by all 8 surrounding oxygen ligands from the channel walls.
Aqvist +30 more
arxiv +5 more sources
Comparison of Langevin and Markov channel noise models for neuronal signal generation [PDF]
, 2009 The stochastic opening and closing of voltage-gated ion channels produces noise in neurons. The effect of this noise on the neuronal performance has been modelled using either approximate or Langevin model, based on stochastic differential equations or an exact model, based on a Markov process model of channel gating.
A. L. Hodgkin +15 more
arxiv +3 more sources
Membranes, 2023 In the inner mitochondrial membrane, several potassium channels that play a role in cell life and death have been identified. One of these channels is the ATP-regulated potassium channel (mitoKATP).
Milena Krajewska +3 more
doaj +1 more source
British Journal of Pharmacology, 2007 ALEXANDER, S.P.H., MATHIE, A. & PETERS, J.A. (2007). Guide to Receptors and Channels (GRAC), 2nd edition (2007 revision). Br. J. Pharmacol., 150 (Suppl. 1), S1–S168.
S P H Alexander +2 more
openaire +4 more sources
Alternative Targets for Modulators of Mitochondrial Potassium Channels
Molecules, 2022 Mitochondrial potassium channels control potassium influx into the mitochondrial matrix and thus regulate mitochondrial membrane potential, volume, respiration, and synthesis of reactive oxygen species (ROS).
Antoni Wrzosek +4 more
doaj +1 more source
Photocatalytic Isomerization of (E)-Anethole to (Z)-Anethole
Molecules, 2022 Natural product (E)-anethole was isomerized to (Z)-anethole in a photocatalytic reaction. For this purpose, a self-designed cheap photoreactor was constructed.
Marvin Korff +4 more
doaj +1 more source
Molecules, 2021 Mitochondria play a key role in energy metabolism within the cell. Potassium channels such as ATP-sensitive, voltage-gated or large-conductance Ca2+-regulated channels have been described in the inner mitochondrial membrane.
Aleksandra Sek +4 more
doaj +1 more source