Results 161 to 170 of about 996,321 (170)

Unfolded Protein Response in Cancer: IRE1α Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability

ACS Medicinal Chemistry Letters, 2015
Kaustav Biswas, Holger Beckmann, Richard Kendall   +2 more
exaly  

Inhibition of kinase and endoribonuclease activity of ERN1/IRE1α affects expression of proliferation related genes in U87 glioma cells

Cell pathology, 2015
Oleksandr N. Minchenko, Dmytro Minchenko, Dariia Tsymbal   +2 more
exaly  

The IRE1 and PERK arms of the unfolded protein response promote survival of rhabdomyosarcoma cells

Cancer Letters, 2020
Nadezda Dolgikh, Susan Logue, Simone Fulda   +2 more
exaly  

Selective Inhibition of IRE1 Signalling mediated by MKC9989: New Insights from Molecular Docking and Molecular Dynamics Simulations

ChemistrySelect, 2019
Leif A Eriksson, Antonio Carlesso
exaly  

Inhibition of IRE1 signaling affects expression of a subset genes encoding for TNF-related factors and receptors and modifies their hypoxic regulation in U87 glioma cells

Cell pathology, 2016
Oleksandr N. Minchenko, Dmytro Minchenko, Oleh V Halkin   +2 more
exaly  

Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive Ligands

ACS Chemical Biology, 2016
Feroz Papa, Theodore Gobillot, Dustin J. Maly   +2 more
exaly  

Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer

Cell Chemical Biology
Minjing Li, Yongliang Liu, Yangfu Jiang
exaly  

IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer

Cell
Xi Chen
exaly  

Inhibition of keloid fibroblast proliferation by artesunate is mediated by targeting the IRE1α/XBP1 signaling pathway and decreasing TGF-β1

Burns
Xiaomei Han, Caixia Hu
exaly  

Inhibition of IRE1α Alleviates Renal Fibrosis and Downregulates M1 Macrophage Activation via the p38 MAPK Pathway

Immunology
Zichan Guo, Yuting Shen, Dingwen Shi
exaly