Results 81 to 90 of about 81,945 (302)

Bright Tin Halide Perovskite Quantum Dots via Organic Dication Compensatory Doping

Angewandte Chemie International Edition, EarlyView.
Tin halide perovskites (THPs) are attractive near‐infrared emitters. Confined THP quantum dots (QDs), however, show low emissivity and valence intraband transitions due to self‐p‐doping. We present aliovalent substitution of cesium with organic dications as a compensation strategy to upshift the Fermi level.
Ole F. Dressler, Paul Golias, John L. Lyons, Stefanie Frick, Sebastian Siol, Sure Ceylan, Sebastian Sabisch, Luca V. Comparetto, Louis Rohrer, Lidiia Dubenska, Amrutha Rajan, Maksym V. Kovalenko   +11 more
wiley   +1 more source

Fighting for their survival: The International Rhino Foundation ensures the survival of rhinos trhough strategic partnerships, targeted protection, and scientifically sound interventions [PDF]

, 2021
The International Rhino Foundation (IRF), based in the United States operates on-the-ground programmes in Africa and Asia where rhinos live in the wild, supporting viable populations of the five remaining rhino species and the communities that coexist ...
Whitlatch for IRF, Christopher
core  

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Regulating IRFs in IFN Driven Disease [PDF]

Frontiers in Immunology, 2019
The Interferon regulatory factors (IRFs) are a family of transcription factors that play pivotal roles in many aspects of the immune response, including immune cell development and differentiation and regulating responses to pathogens. Three family members, IRF3, IRF5, and IRF7, are critical to production of type I interferons downstream of pathogen ...
openaire   +3 more sources

Distinct Molecular Pathways Supporting Sjögren Disease Clusters and Disease Progression

Arthritis &Rheumatology, EarlyView.
Objective Sjögren disease (SjD) is a heterogeneous autoimmune disease. We aimed to investigate blood transcriptomic signatures and disease progression among three recently defined clusters of patients with SjD: (1) B cell active disease with low symptom burden (BALS), (2) high systemic activity (HSA), and (3) low systemic activity with high symptom ...
Sacha E. Silva‐Saffar, Yann Nguyen, Raphaèle Seror, Jacques‐Eric Gottenberg, Anna Niarakis, Xavier Mariette, Gaetane Nocturne   +6 more
wiley   +1 more source

Direct observations of negative ions on the Lunar surface by Chang'E-6

Communications Earth & Environment
The solar wind can interact directly with the surface of airless bodies like the Moon. The interaction causes sputtering of surface materials and solar wind ions are also partially backscattered to space. Particles leaving the surface can have any charge-
Martin Wieser, Aibing Zhang, Romain Canu-Blot, Wengjing Wang, Gabriella Stenberg Wieser, Lianghai Xie, Stas Barabash, Tianhua Zhong, Xiao-Dong Wang, Yongliao Zou, Máté Kerényi, Weibin Wen, Charles Lue, Chi Wang   +13 more
doaj   +1 more source

Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection.

PLoS Pathogens, 2011
Interferon regulatory factor (IRF)-1 is an immunomodulatory transcription factor that functions downstream of pathogen recognition receptor signaling and has been implicated as a regulator of type I interferon (IFN)-αβ expression and the immune response ...
James D Brien, Stephane Daffis, Helen M Lazear, Hyelim Cho, Mehul S Suthar, Michael Gale, Michael S Diamond   +6 more
doaj   +1 more source

Optimizing Efficacy to Safety Ratio of Glucocorticoids in Rheumatoid Arthritis Models by Leveraging Peroxisome Proliferator–Activated Nuclear Receptor‐α Agonism

Arthritis &Rheumatology, EarlyView.
Objective Glucocorticoids remain essential therapies for immune and inflammatory diseases such as rheumatoid arthritis (RA) but are notorious for their metabolic side effects. Given the anti‐inflammatory and metabolically favorable actions of peroxisome proliferator–activated nuclear receptor (PPAR) agonists, we investigated whether PPARα agonism could
Lisa L. Koorneef, Elisabeth Gilis, Dorien Clarisse, Daria Fijalkowska, Sara Dufour, Julie Coudeneys, Bert Luyckx, Annick Verhee, Jonathan Thommis, Candice Vanden Bussche, Ulf Müller‐Ladner, Elena Neumann, Matthias Kerkhofs, Guillaume Planckaert, Simon Devos, Leander Meuris, Dirk Elewaut, Karolien De Bosscher   +17 more
wiley   +1 more source

ELL2 Is Required for the Growth and Survival of AR-Negative Prostate Cancer Cells

Cancer Management and Research, 2020
Zhi Wang,1,2 Laura E Pascal,2 Uma R Chandran,3 Srilakshmi Chaparala,3 Shidong Lv,2,4 Hui Ding,2 Lin Qi,1 Zhou Wang2,5– 7 1Department of Urology, Xiangya Hospital of Central South University, Changsha, People’s Republic of China; 2Department ...
Wang Z, Pascal LE, Chandran UR, Chaparala S, Lv S, Ding H, Qi L, Wang Z   +7 more
doaj  

Down-regulated GATA-1 up-regulates interferon regulatory factor 3 in lung adenocarcinoma

Scientific Reports, 2017
Interferon regulatory factor 3 (IRF-3) is widely known for its prompt response against viral infection by activating the interferon system. We previously reported that E2F1, Sp1 and Sp3 regulated transcriptional activity of IRF-3.
Lu-Lu Wang, Zheng-Sen Chen, Wen-Di Zhou, Jin Shu, Xiao-Hua Wang, Rui Jin, Li-Li Zhuang, Mir Alireza Hoda, Hao Zhang, Guo-Ping Zhou   +9 more
doaj   +1 more source