Results 71 to 80 of about 81,945 (302)
Deciphering the role of the Sch9 serine/threonine kinase in Scedosporium apiospermum
Frontiers in Fungal BiologyScedosporium apiospermum is an emerging opportunistic fungal pathogen, primarily affecting immunocompromised individuals. Notably, it ranks second among filamentous fungi infecting cystic fibrosis (CF) patients. Infections caused by S.
Samar Kabbara +9 more
doaj +1 more source
Global and Distinct Targets of IRF-5 and IRF-7 during Innate Response to Viral Infection [PDF]
Journal of Biological Chemistry, 2004 The interferon regulatory factors (IRF) are transcriptional mediators of cellular response to viral invasion that play a critical role in the innate antiviral defense. Two of these factors, IRF-5 and IRF-7, play a critical role in the induction of interferon (IFNA) genes in infected cells; they are expressed constitutively in monocytes, B cells, and ...
Betsy J, Barnes +5 more
openaire +2 more sources
IFP35 expression is upregulated by constitutively active forms of IRF-3 and IRF-7 in HeLa cells.
, 2013 HeLa cells were transfected with the expression plasmids encoding IRF-1, IRF-2 and constitutively active forms of IRF-3, IRF-5 and IRF-7. At 48 h after transfection, whole cell extracts were prepared and Western blot analysis was performed with ...
Qinglin Ma (295758) +6 more
core +1 more source
Delaying the Inevitable? U.S. Screwworm Closures and Feeder Cattle Market Dynamics
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT Biosecurity trade restrictions are commonly framed as preventive measures, yet in many settings they function primarily as policies of delay: they impose immediate market costs while only postponing the arrival of biological risks. This paper evaluates that intertemporal tradeoff using the 2024–2025 US suspension of live cattle imports from ...
Shelby Sumner +3 more
wiley +1 more source
IκB kinase-ε-mediated phosphorylation triggers IRF-1 degradation in breast cancer cells
Neoplasia: An International Journal for Oncology Research, 2020 Interferon Regulatory Factors (IRFs) are key regulators of immunity, cell survival and apoptosis. IRF transcriptional activity and subcellular localization are tightly regulated by posttranscriptional modifications including phosphorylation.
Anna Lisa Remoli +8 more
doaj +1 more source
Type I interferons and interferon regulatory factors regulate TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected macrophages. [PDF]
PLoS ONE, 2009 TNF-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family that participates in HIV-1 pathogenesis through the depletion of CD4+ T cells.
Yunlong Huang +6 more
doaj +1 more source
Cost Pass‐Through in Crisis: Evidence From the German Malt‐Beer Supply Chain
Agribusiness, EarlyView.Abstract Global agri‐food supply chains are increasingly exposed to geopolitical shocks, climate volatility, and market consolidation, factors that disrupt traditional price relationships and reshape market power dynamics. Nowhere is this more visible than in the brewing sector, where agricultural raw materials meet complex industrial processing and ...
Nikolas Bublik, Lukáš Čechura
wiley +1 more source
Statistics of high-altitude and high-latitude O+ ion outflows observed by Cluster/CIS [PDF]
Annales Geophysicae, 2005 The persistent outflows of O+ ions observed by the Cluster CIS/CODIF instrument were studied statistically in the high-altitude (from 3 up to 11 RE) and high-latitude (from 70 to ~90 deg invariant latitude, ILAT) polar region.
S. Arvelius +10 more
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.Nitrogen K‐edge XAS and RIXS reveal signatures of structural and electronic relaxation in the photo‐induced spin‐crossover cascade of iron‐(II)‐tris(bipyridine). Oscillations of the 1s→π∗$1{\rm s} \rightarrow \pi ^*$ transition energy are correlated with the transient elongation of the Fe─N bonds.
Sebastian Eckert +25 more
wiley +1 more source
IRF-7C has oncogenic potential.
, 2013 (A) IRF-7C causes anchorage-independent growth of NIH 3T3 cells. A soft-agar assay was used for an IRF-7C stably expressing cell line established in NIH 3T3 cells.
Dongsheng Xu (84949) +3 more
core +1 more source