Results 21 to 30 of about 3,833 (161)

Therapeutic potential of plant iridoids in depression: a review

Pharmaceutical Biology, 2022
Context Depression is a mental disorder characterized by low mood, reduced interest, impaired cognitive function, and vegetative symptoms such as sleep disturbances or poor appetite.
Yaoyao Kou, Zhihao Li, Tong Yang, Xue Shen, Xin Wang, Haopeng Li, Kun Zhou, Luyao Li, Zhaodi Xia, Xiaohui Zheng, Ye Zhao   +10 more
doaj   +1 more source

Iridoids and active ones in patrinia: A review

Heliyon, 2023
Iridoid is a special class of monoterpenoids, whose basic skeleton is the acetal derivative of antinodilaldehyde with a bicyclic H-5/H-9β, β-cisfused cyclopentan pyran ring.
Li Wang, Xinjing Meng, Huihui Zhou, Yuhang Liu, Yadan Zhang, Haiyang Liang, Gaixia Hou, Wenyi Kang, Zhenhua Liu   +8 more
doaj   +1 more source

Antimicrobial and Immunomodulating Activities of Two Endemic Nepeta Species and Their Major Iridoids Isolated from Natural Sources

Pharmaceuticals, 2021
Two Balkan Peninsula endemics, Nepeta rtanjensis and N. argolica subsp. argolica, both characterized by specialized metabolite profiles predominated by iridoids and phenolics, are differentiated according to the stereochemistry of major iridoid aglycone ...
Neda Aničić, Uroš Gašić, Feng Lu, Ana Ćirić, Marija Ivanov, Bojan Jevtić, Milena Dimitrijević, Boban Anđelković, Marijana Skorić, Jasmina Nestorović Živković, Yingle Mao, Jia Liu, Chunping Tang, Marina Soković, Yang Ye, Danijela Mišić   +15 more
doaj   +1 more source

Iridoids from Stachys byzantina K. Koch (Lamb's Ears) and Stachys germanica L. (Downy Woundwort)

European Pharmaceutical Journal, 2021
Iridoids are a class of secondary metabolites found in a wide variety of plants. Iridoids are typically found in plants as glycosides, most often found to glucose. The genus Stachys L.
Háznagy-Radnai E., Czigle Sz., Máthé I.   +2 more
doaj   +1 more source

Iridoids from Globularia dumulosa [PDF]

Zeitschrift für Naturforschung C, 2003
Two new iridoids, 10-O-benzoylglobularigenin (1) and dumuloside (2) were isolated from the aerial parts of Globularia dumulosa together with seven known iridoid glucosides, davisioside (3), aucubin (4), melampyroside (5), catalpol (6), 10-O-benzoylcatalpol (7), alpinoside (8) and deacetylalpinoside (9).
Kirmizibekmez, H, Akbay, P, Sticher, O, Çaliş, I.   +3 more
openaire   +3 more sources

Iridoids, Flavonoids, and Antioxidant Capacity of Cornus mas, C. officinalis, and C. mas × C. officinalis Fruits

Biomolecules, 2021
The fruits of Cornus mas and Cornus officinalis have been known and appreciated in folk medicine for years and have a high biological value, which is mainly connected with their polyphenols and iridoids content. However, hybrids of C.
Svitlana Klymenko, Alicja Zofia Kucharska, Anna Sokół-Łętowska, Narcyz Piórecki, Dominika Przybylska, Olga Grygorieva   +5 more
doaj   +1 more source

Iridoids from Galium aparine [PDF]

Pharmaceutical Biology, 2001
The isolation and UV, IR, 1 H- and 13 C-NMR data of asperulosidic acid, 10-deacetylasperulosidic acid from Galium aparine L. aerial parts are reported.
Deliorman, D, Calis, I, Ergun, F
openaire   +3 more sources

Iridoids and bis-iridoids from Patrinia scabiosaefolia

RSC Advances, 2017
Ten new iridoids, patriscabioins A–J (1–10), and three unique bis-iridoids, patriscabiobisins A–C (11–13), together with seven known analogues, have been identified from whole plants of Patrinia scabiosaefolia.
Zhen-Hua Liu, Bo Hou, Liu Yang, Rui-Jing Ma, Jin-Yu Li, Jiang-Miao Hu, Jun Zhou   +6 more
openaire   +4 more sources

Establishing the Role of Iridoids as Potential Kirsten Rat Sarcoma Viral Oncogene Homolog G12C Inhibitors Using Molecular Docking; Molecular Docking Simulation; Molecular Mechanics Poisson–Boltzmann Surface Area; Frontier Molecular Orbital Theory; Molecular Electrostatic Potential; and Absorption, Distribution, Metabolism, Excretion, and Toxicity Analysis

Molecules, 2023
The RAS gene family is one of the most frequently mutated oncogenes in human cancers. In KRAS, mutations of G12D and G12C are common. Here, 52 iridoids were selected and docked against 8AFB (KRAS G12C receptor) using Sotorasib as the standard. As per the
Mubarak A. Alamri, Abdullah S. Alawam, Mohammed Merae Alshahrani, Sarkar M. A. Kawsar, Prinsa, Supriyo Saha   +5 more
doaj   +1 more source

Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome

Cellular Physiology and Biochemistry, 2017
Background/Aims: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women, and it is usually characterized by chronic inflammation, oxidative stress, and altered microRNA expression. The aim of this study is to investigate how the effects
Tao Zuo, Minghui Zhu, Wenming Xu, Zhixia Wang, Hang Song   +4 more
doaj   +1 more source