Results 11 to 20 of about 1,583 (164)

Isocyanides Versus Nitriles: Divergent Hydrogen Bonding Behavior Driven by the Balance Between Dispersive and Electrostatic Forces. [PDF]

Chemphyschem
While isocyanides favor σ‐type hydrogen bonding, as illustrated by t‐BuNC···H2O (top), nitriles prefer π‐type hydrogen bonding, as illustrated by t‐BuCN···H2O (bottom). The σ‐type complex is characterized by a larger OH vibrational downshift due to more efficient charge transfer, whereas the π‐type complex is mainly stabilized by dispersion and thus ...
Kanzow A, Suhm MA, Bödecker M.
europepmc   +2 more sources

Synthesis of Depsipeptides via Isocyanide-Based Consecutive Bargellini–Passerini Multicomponent Reactions

SynOpen, 2021
An efficient and straightforward approach has been established for the preparation of a new class of depsipeptide structures via isocyanide-based consecutive Bargellini–Passerini multicomponent reactions.
Hassan Farhid, Mohammad Mahdi Rostami, Ahmad Shaabani, Behrouz Notash   +3 more
doaj   +1 more source

Multicomponent Reactions of Isocyanides for the Preparation of Low Molecular Weight Gelators: Preliminary Studies

Chemistry Proceedings, 2021
Low molecular weight gelators, LMWGs, are small molecules that can self-associate in organic solvents or in water to form fibrous supramolecular architectures and three-dimensional networks that present important applications in several fields.
José L. Ramiro, Carlos F. Marcos, Ana G. Neo   +2 more
doaj   +1 more source

Three-Component Reaction of 3-Arylidene-3H-Indolium Salts, Isocyanides, and Alcohols

Frontiers in Chemistry, 2019
A novel isocyanide-based multicomponent synthesis of alkyl aryl(indol-3-yl)acetimidates has been established. Starting from aryl(indol-3-yl)methylium tetrafluoroborates, aromatic isocyanides and alcohols, the imidates were obtained in moderate to very ...
Nikita E. Golantsov, Hung M. Nguyen, Alexandra S. Golubenkova, Alexey V. Varlamov, Erik V. Van der Eycken, Erik V. Van der Eycken, Leonid G. Voskressensky   +6 more
doaj   +1 more source

Semisynthesis of 6β-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction

Chemistry Proceedings, 2022
A semisynthesis of 6β-acetoxyvouacapane-1,5-disusbtituted tetrazoles derivatives from the leaves of Caesalpinia platyloba by using the Ugi-azide multicomponent reaction as a key step reaction is described. To our knowledge, this is the first report where
Gabriela Servín-García, Luis Chacón-García, Joaquín González-Marrero, Mariana Macías-Alonso, Mario A. Gómez-Hurtado, Gabriela Rodríguez-García, Rosa E. del Río, Carlos J. Cortés-García   +7 more
doaj   +1 more source

Pyrrolidinodiones in Enol-Ugi, Enol-Passerini, and Anomalous Enol-Passerini Condensations

Proceedings, 2019
In continuation of our recent research on the development of novel multicomponent reactions with isocyanides, we have used, for the first time, enols as the acid components in Ugi- and Passerini-type reactions. Thus, electron-poor pyrrolidinodiones react
Ana G. Neo, Carlos F. Marcos
doaj   +1 more source

Isocyanide 2.0

Green Chemistry, 2020
Isocyanides are important chemicals, with limited availability, thus reducing their general use. Our highly improved isocyanide synthesis performed on mole to μ-mole scale, individually or in a 96-well parallel fashion enables unprecedented exploration of novel chemistries.
Pravin Patil, Maryam Ahmadian-Moghaddam, Alexander Dömling   +2 more
openaire   +3 more sources

Cyclization of Activated Methylene Isocyanides with Methyl N(N),N′-Di(tri)substituted Carbamimidothioate: A Novel Entry for the Synthesis of N,1-Aryl-4-tosyl/ethoxycarbonyl-1H-imidazol-5-amines

SynOpen, 2019
Base-induced cyclization of active methylene isocyanides with carbamimidothioates for the synthesis of N,1-aryl-4-tosyl/ethylcarboxy-1H-imidazol-5-amines is reported.
Dukanya Dukanya, Toreshettahally R. Swaroop, Shobith Rangappa, Kanchugarakoppal S. Rangappa, Basappa Basappa   +4 more
doaj   +1 more source

Recent Advances in Palladium-Catalyzed Isocyanide Insertions

Molecules, 2020
Isocyanides have long been known as versatile chemical reagents in organic synthesis. Their ambivalent nature also allows them to function as a CO-substitute in palladium-catalyzed cross couplings.
Jurriën W. Collet, Thomas R. Roose, Bram Weijers, Bert U. W. Maes, Eelco Ruijter, Romano V. A. Orru   +5 more
doaj   +1 more source

The Chemistry of Isocyanides, their MultiComponent Reactions and their Libraries

Molecules, 2003
The first century of isocyanide chemistry, which was then still a rather empty part of Organic Chemistry, began in 1859. In 1958 isocyanides became generally available by dehydration the formylamines.
A. Dömling, B. Werner, I. Ugi
doaj   +1 more source