Results 61 to 70 of about 1,583 (164)
Silent Partners in the Mill: Unveiling the Role of Additives in Mechanochemical Synthesis
Chemistry – A European Journal, Volume 32, Issue 9, 2 March 2026.Mechanochemistry offers a sustainable, solvent‐free alternative to traditional synthesis, often enhanced by additives in a process known as additive‐assisted grinding. This review discusses how various additives, including liquids, ionic solids, and advanced materials like ionic liquids and piezoelectric compounds, improve reaction efficiency ...
Johanna Breinsperger +3 more
wiley +1 more source
Metal Nanocluster‐Based Manufacturing of 2D Film With an Insulator‐to‐Conductor Tunability
Aggregate, Volume 7, Issue 3, March 2026.The voltage‐dependent assembly on interdigitated microelectrodes is based on Au25 nanoclusters (NCs): crystallizing at 0.5 V, NC‐based filming at 1.3 V, and nanocrystal‐based filming at 2.6 V. The film formed at 2.6 V can be varied from an insulator to a conductor (from ∞ to ∼0.3 Ω), exhibiting unique electrothermal and current‐limiting functionalities.
Hao Liu +8 more
wiley +1 more source
Phosphoramidate and Silyl Amine Mediated Synthesis of Isocyanide Cyclopentadienone Iron Complexes
Helvetica Chimica Acta, Volume 109, Issue 3, March 2026.Carbonyl ligands in cyclopentadienone iron complexes are replaced by isocyanide ligands without using free, malodorous isocyanides. The reaction takes place via an Aza‐Wittig‐type reaction starting from primary amines, employing either phosphoramidates or silyl amines as intermediate reagents.
André Bütikofer +3 more
wiley +1 more source
Magnetic Resonance in Chemistry, Volume 64, Issue 3, Page 324-332, March 2026.We report the results from a kinetic and mechanistic investigation of an inverse‐electron‐demand Diels–Alder (IEDDA) cycloaddition involving an oxazole‐type diene synthesized via an Ugi–Zhu multicomponent reaction (UZ‐3CR). ABSTRACT Pyridines are a crucial class of heterocycles with widespread applications in natural products, pharmaceuticals, and ...
Galdina V. Suárez‐Moreno +6 more
wiley +1 more source
Microwave-Assisted Synthesis of Novel Functionalized Ketenimines and Azadienes via a Solvent-Free Reaction of Isatoic Anhydride, Alkyl-Isocyanides and Dialkyl Acetylenedicarboxylates [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2019 Ketenimines and azadienes are transient intermediates in organic chemistry especially in elimination-addition processes and in the formation of heterocyclic systems.
Samira Arab-Salmanabadi
doaj
Turn‐Induction in Peptides Incorporating Novel Cyrene‐Derived α,α‐Disubstituted Amino Acid
Journal of Peptide Science, Volume 32, Issue 3, March 2026.Novel chiral cyrene‐derived Cyr residues were incorporated into peptides. The α,α‐disubstituted amino acid residue was introduced using the Ugi reaction. X‐ray crystallographic analysis of R‐ and S‐Cyr residues indicated preference to adopt left‐ and right‐handed α‐helical conformations, respectively.
Kajumee Bora Bhowal +2 more
wiley +1 more source
Direct‐to‐Biology: Streamlining the Path From Chemistry to Biology in Drug Discovery
ChemMedChem, Volume 21, Issue 4, 25 February 2026.Crude yet clever: Direct‐to‐biology workflows exploit nanoscale synthesis and plate‐based assays to accelerate hit discovery, save precious intermediates, and rethink early drug discovery. Direct‐to‐biology (D2B) has emerged as a transformative concept in early drug discovery, defined by the direct on‐target screening of crude reaction mixtures without
Ariane F. Hübner, Fabian Barthels
wiley +1 more source
Passerini Reactions on Biocatalytically Derived Chiral Azetidines
Molecules, 2016 The purpose of this study was to explore a series of Passerini reactions on a biocatalytically derived enantiopure azetidine-2-carboxyaldehyde in order to obtain, in a diastereoselective manner, polyfunctionalised derivatives having the potential to be ...
Lisa Moni +6 more
doaj +1 more source
Synthesis of Benzopyranophenazines via Isocyanide-Based Three-Component Reactions
E-Journal of Chemistry, 2012 Benzo[a]pyrano[2,3-c]phenazines were synthesized in good yields by a three-component reaction of benzo[a]phenazin-5-oles, isocyanides and dialkyl acetylendicarboxylates In refluxing ethanol.
Ayoob Bazgir, Ali Mohammad Astaraki
doaj +1 more source
Molecules, 2011 We have recently reported a novel multicomponent reaction between arylacetic acids and isocyanides, affording α-acyloxyacrylamides through an unusual mechanism.
Renata Riva, Andrea Basso, Luca Banfi
doaj +1 more source