Results 21 to 30 of about 1,529 (123)
Charting the equine miRNA landscape: An integrated pipeline and browser for annotating, quantifying, and visualizing expression. [PDF]
PLoS GeneticsMicroRNAs (miRNAs) are essential regulators of gene expression, yet few comprehensive databases exist for miRNA expression in non-model species, limiting our ability to characterize their roles in gene regulation, development, and disease.
Jonah N Cullen +34 more
doaj +2 more sources
MicroRNA Isoforms Contribution to Melanoma Pathogenesis
Non-Coding RNA, 2021 Cutaneous melanoma (CM) is the most lethal tumor among skin cancers, and its incidence is constantly increasing. A deeper understanding of the molecular processes guiding melanoma pathogenesis could improve diagnosis, treatment and prognosis.
Elisabetta Broseghini +3 more
doaj +1 more source
isomiRs: Increasing Evidences of isomiRs Complexity in Plant Stress Functional Biology
Frontiers in Plant Science, 2015 Peter Ralph +2 more
exaly +3 more sources
Discovery of isomiRs in PBMCs of diseased vis-à-vis healthy Indian water buffaloes [PDF]
ExRNA, 2019 Background: MicroRNA isoforms are the variants of a canonical miRNA-sequence with alteration at the 3` or 5` termini due to addition, deletion and/or substitution of nucleotide. The present study aims at identifying the isomiRs of the expressed miRNAs in
Jasdeep Kaur Dhanoa +5 more
doaj +1 more source
The FEBS Journal, Volume 290, Issue 24, Page 5692-5703, December 2023., 2023 MicroRNAs (miRNAs) are small noncoding RNAs that control essential cellular processes. For several decades, the molecular mechanisms underlying the functions and biogenesis of miRNAs have been clarified, whereas the molecular dynamics of miRNAs remain poorly understood.
Satoshi Oikawa +3 more
wiley +1 more source
New Phytologist, Volume 240, Issue 3, Page 1034-1051, November 2023., 2023 Summary MicroRNAs (miRNAs) are important regulators of plant biological processes, including soybean nodulation. One miRNA, miR4407, was identified in soybean roots and nodules. However, the function of miR4407 in soybean is still unknown. MiR4407, unique to soybean, positively regulates lateral root emergence and root structures and represses a root ...
Kejing Fan +6 more
wiley +1 more source
Plant IsomiR Atlas: Large Scale Detection, Profiling, and Target Repertoire of IsomiRs in Plants
Frontiers in Plant Science, 2019 microRNAs (miRNAs) play an important role as key regulators controlling the post-transcriptional events in plants across development, abiotic and biotic stress, tissue polarity and also in defining the evolutionary basis of the origin of the post ...
Kun Yang +4 more
doaj +1 more source
Beta cell 5'-shifted isomiRs are candidate regulatory hubs in type 2 diabetes. [PDF]
PLoS ONE, 2013 Next-generation deep sequencing of small RNAs has unveiled the complexity of the microRNA (miRNA) transcriptome, which is in large part due to the diversity of miRNA sequence variants ("isomiRs").
Jeanette Baran-Gale +3 more
doaj +1 more source
EpisomiR, a New Family of miRNAs, and Its Possible Roles in Human Diseases
Biomedicines, 2022 MicroRNAs (miRNAs) are synthesized through a canonical pathway and play a role in human diseases, such as cancers and cardiovascular, neurodegenerative, psychiatric, and chronic inflammatory diseases.
Yasuko Arao +7 more
doaj +1 more source
Tumor classification and biomarker discovery based on the 5’isomiR expression level
BMC Cancer, 2019 Background The miRNA isoforms (isomiRs) have been suggested to regulate the same pathways as the canonical miRNA and play an important biological role in miRNA-mediated gene regulation.
Shengqin Wang +3 more
doaj +1 more source