Results 31 to 40 of about 22,403 (243)
eLife, 2021 Volatile organic compounds (VOCs) from ‘emitting’ plants inform the ‘receiving’ (listening) plants of impending stresses or simply of their presence. However, the receptors that allow receivers to detect the volatile cue are elusive. Most likely, plants (
Deborah Giordano +3 more
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Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents? [PDF]
, 2006 It has been postulated that endothelial cell injury is the initiating event in the pathogenesis of systemic sclerosis, causing attraction, attachment, migration and infiltration of activated T-cells and subsequent production of cytokines and growth ...
Derk, Chris T., Jimenez, Sergio A.
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The Potential of Isoprenoids in Adjuvant Cancer Therapy to Reduce Adverse Effects of Statins
Frontiers in Pharmacology, 2019 The mevalonate pathway provides sterols for membrane structure and nonsterol intermediates for the post-translational modification and membrane anchorage of growth-related proteins, including the Ras, Rac, and Rho GTPase family.
Huanbiao Mo +5 more
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mSystems, 2023 Methanogenic archaea possess diverse metabolic characteristics and are an ecologically and biotechnologically important group of anaerobic microorganisms.
Ruth-Sophie Taubner +12 more
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Divergent strategy for the synthesis of α-aryl-substituted fosmidomycin analogues [PDF]
, 2007 Fosmidomycin is the first representative of a new class of antimalarial drugs acting through inhibition of 1-deoxy-D-xylulose 5-phosphate ( DOXP) reductoisomerase (DXR), an essential enzyme in the non-mevalonate pathway for the synthesis of isoprenoids ...
Devreux, Vincent +5 more
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Current Metabolic Engineering Strategies for Photosynthetic Bioproduction in Cyanobacteria
Microorganisms, 2023 Cyanobacteria are photosynthetic microorganisms capable of using solar energy to convert CO2 and H2O into O2 and energy-rich organic compounds, thus enabling sustainable production of a wide range of bio-products.
Alessandro Satta +2 more
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Microbial monoterpene transformations – A review
Frontiers in Microbiology, 2014 Isoprene and monoterpenes constitute a significant fraction of new plant biomass. Emission rates into the atmosphere alone are estimated to be over 500 Tg per year. These natural hydrocarbons are mineralized annually in similar quantities.
Robert eMarmulla, Jens eHarder
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Metabolites, 2022 Geranylgeranoic acid (GGA), developed as a preventive agent against second primary hepatoma, has been reported to be biosynthesized via the mevalonate pathway in human hepatoma-derived cells.
Yuki Tabata, Yoshihiro Shidoji
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From Zn to Mn: the study of novel manganese-binding groups in the search for new drugs against tuberculosis. [PDF]
, 2011 In most eubacteria, apicomplexans, and most plants, including the causal agents for diseases such as malaria, leprosy, and tuberculosis, the methylerythritol phosphate pathway is the route for the biosynthesis of the C(5) precursors to the essential ...
de Oliveira, César Augusto F +3 more
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mSystems, 2019 Zymomonas mobilis is an aerotolerant anaerobe and prolific ethanologen with attractive characteristics for industrial bioproduct generation. However, there is currently insufficient knowledge of the impact that environmental factors have on flux through ...
Julia I. Martien +6 more
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